6EMX
X-ray structure of the N15'C mutant of GLIC in complex with bromoform
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004888 | molecular_function | transmembrane signaling receptor activity |
| A | 0005216 | molecular_function | monoatomic ion channel activity |
| A | 0005230 | molecular_function | extracellular ligand-gated monoatomic ion channel activity |
| A | 0006811 | biological_process | monoatomic ion transport |
| A | 0016020 | cellular_component | membrane |
| A | 0034220 | biological_process | monoatomic ion transmembrane transport |
| B | 0004888 | molecular_function | transmembrane signaling receptor activity |
| B | 0005216 | molecular_function | monoatomic ion channel activity |
| B | 0005230 | molecular_function | extracellular ligand-gated monoatomic ion channel activity |
| B | 0006811 | biological_process | monoatomic ion transport |
| B | 0016020 | cellular_component | membrane |
| B | 0034220 | biological_process | monoatomic ion transmembrane transport |
| C | 0004888 | molecular_function | transmembrane signaling receptor activity |
| C | 0005216 | molecular_function | monoatomic ion channel activity |
| C | 0005230 | molecular_function | extracellular ligand-gated monoatomic ion channel activity |
| C | 0006811 | biological_process | monoatomic ion transport |
| C | 0016020 | cellular_component | membrane |
| C | 0034220 | biological_process | monoatomic ion transmembrane transport |
| D | 0004888 | molecular_function | transmembrane signaling receptor activity |
| D | 0005216 | molecular_function | monoatomic ion channel activity |
| D | 0005230 | molecular_function | extracellular ligand-gated monoatomic ion channel activity |
| D | 0006811 | biological_process | monoatomic ion transport |
| D | 0016020 | cellular_component | membrane |
| D | 0034220 | biological_process | monoatomic ion transmembrane transport |
| E | 0004888 | molecular_function | transmembrane signaling receptor activity |
| E | 0005216 | molecular_function | monoatomic ion channel activity |
| E | 0005230 | molecular_function | extracellular ligand-gated monoatomic ion channel activity |
| E | 0006811 | biological_process | monoatomic ion transport |
| E | 0016020 | cellular_component | membrane |
| E | 0034220 | biological_process | monoatomic ion transmembrane transport |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 2 |
| Details | binding site for residue CL A 401 |
| Chain | Residue |
| A | PHE78 |
| A | ARG85 |
| site_id | AC2 |
| Number of Residues | 3 |
| Details | binding site for residue NA A 402 |
| Chain | Residue |
| A | PRO68 |
| A | ILE71 |
| A | ILE73 |
| site_id | AC3 |
| Number of Residues | 1 |
| Details | binding site for residue NA A 403 |
| Chain | Residue |
| D | HOH503 |
| site_id | AC4 |
| Number of Residues | 1 |
| Details | binding site for residue MBR A 404 |
| Chain | Residue |
| A | THR255 |
| site_id | AC5 |
| Number of Residues | 1 |
| Details | binding site for residue CL B 401 |
| Chain | Residue |
| B | PHE78 |
| site_id | AC6 |
| Number of Residues | 4 |
| Details | binding site for residue NA B 402 |
| Chain | Residue |
| B | ILE71 |
| B | TRP72 |
| B | ILE73 |
| B | PRO68 |
| site_id | AC7 |
| Number of Residues | 1 |
| Details | binding site for residue MBR B 403 |
| Chain | Residue |
| B | THR255 |
| site_id | AC8 |
| Number of Residues | 2 |
| Details | binding site for residue NA C 401 |
| Chain | Residue |
| C | PRO68 |
| C | ILE71 |
| site_id | AC9 |
| Number of Residues | 2 |
| Details | binding site for residue MBR C 402 |
| Chain | Residue |
| C | PRO120 |
| C | THR255 |
| site_id | AD1 |
| Number of Residues | 1 |
| Details | binding site for residue CL D 401 |
| Chain | Residue |
| D | PHE78 |
| site_id | AD2 |
| Number of Residues | 2 |
| Details | binding site for residue NA D 402 |
| Chain | Residue |
| D | PRO68 |
| D | ILE71 |
| site_id | AD3 |
| Number of Residues | 2 |
| Details | binding site for residue MBR D 403 |
| Chain | Residue |
| D | THR255 |
| D | ILE258 |
| site_id | AD4 |
| Number of Residues | 1 |
| Details | binding site for residue CL E 401 |
| Chain | Residue |
| E | PHE78 |
| site_id | AD5 |
| Number of Residues | 2 |
| Details | binding site for residue NA E 402 |
| Chain | Residue |
| E | PRO68 |
| E | ILE71 |
| site_id | AD6 |
| Number of Residues | 4 |
| Details | binding site for residue MBR E 403 |
| Chain | Residue |
| B | HOH501 |
| C | HOH501 |
| E | SER230 |
| E | HOH502 |
| site_id | AD7 |
| Number of Residues | 5 |
| Details | binding site for residue MBR E 404 |
| Chain | Residue |
| E | PRO120 |
| E | TYR197 |
| E | ILE201 |
| E | THR255 |
| E | HOH508 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 990 |
| Details | TOPO_DOM: Periplasmic => ECO:0000255 |
| Chain | Residue | Details |
| A | GLN2-GLN193 | |
| E | ASN245-MET252 | |
| A | ASN245-MET252 | |
| B | GLN2-GLN193 | |
| B | ASN245-MET252 | |
| C | GLN2-GLN193 | |
| C | ASN245-MET252 | |
| D | GLN2-GLN193 | |
| D | ASN245-MET252 | |
| E | GLN2-GLN193 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 530 |
| Details | TRANSMEM: Helical |
| Chain | Residue | Details |
| A | TYR194-PHE216 | |
| C | SER220-THR244 | |
| C | THR253-VAL281 | |
| C | PRO285-PHE317 | |
| D | TYR194-PHE216 | |
| D | SER220-THR244 | |
| D | THR253-VAL281 | |
| D | PRO285-PHE317 | |
| E | TYR194-PHE216 | |
| E | SER220-THR244 | |
| E | THR253-VAL281 | |
| A | SER220-THR244 | |
| E | PRO285-PHE317 | |
| A | THR253-VAL281 | |
| A | PRO285-PHE317 | |
| B | TYR194-PHE216 | |
| B | SER220-THR244 | |
| B | THR253-VAL281 | |
| B | PRO285-PHE317 | |
| C | TYR194-PHE216 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 20 |
| Details | TOPO_DOM: Cytoplasmic => ECO:0000255 |
| Chain | Residue | Details |
| A | TRP217-THR219 | |
| E | GLU282-GLN284 | |
| A | GLU282-GLN284 | |
| B | TRP217-THR219 | |
| B | GLU282-GLN284 | |
| C | TRP217-THR219 | |
| C | GLU282-GLN284 | |
| D | TRP217-THR219 | |
| D | GLU282-GLN284 | |
| E | TRP217-THR219 |
