Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003676 | molecular_function | nucleic acid binding |
| A | 0003964 | molecular_function | RNA-directed DNA polymerase activity |
| A | 0004523 | molecular_function | RNA-DNA hybrid ribonuclease activity |
| A | 0006278 | biological_process | RNA-templated DNA biosynthetic process |
| B | 0003964 | molecular_function | RNA-directed DNA polymerase activity |
| B | 0006278 | biological_process | RNA-templated DNA biosynthetic process |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 13 |
| Details | binding site for residue T27 A 701 |
| Chain | Residue |
| A | PRO95 |
| A | HIS235 |
| A | PRO236 |
| A | TYR318 |
| B | HOH616 |
| A | LEU100 |
| A | LYS101 |
| A | LYS103 |
| A | TYR181 |
| A | TYR188 |
| A | PHE227 |
| A | TRP229 |
| A | LEU234 |
| site_id | AC2 |
| Number of Residues | 11 |
| Details | binding site for residue BA5 A 702 |
| Chain | Residue |
| A | ASP443 |
| A | GLU478 |
| A | ASP498 |
| A | HIS539 |
| A | ASP549 |
| A | MG703 |
| A | MG704 |
| A | HOH852 |
| A | HOH888 |
| A | HOH923 |
| A | HOH984 |
| site_id | AC3 |
| Number of Residues | 6 |
| Details | binding site for residue MG A 703 |
| Chain | Residue |
| A | ASP443 |
| A | ASP549 |
| A | BA5702 |
| A | MG704 |
| A | HOH852 |
| A | HOH888 |
| site_id | AC4 |
| Number of Residues | 5 |
| Details | binding site for residue MG A 704 |
| Chain | Residue |
| A | ASP443 |
| A | GLU478 |
| A | ASP498 |
| A | BA5702 |
| A | MG703 |
| site_id | AC5 |
| Number of Residues | 5 |
| Details | binding site for residue SO4 A 705 |
| Chain | Residue |
| A | MET41 |
| A | LYS73 |
| A | TYR146 |
| A | PRO150 |
| A | GLN151 |
| site_id | AC6 |
| Number of Residues | 4 |
| Details | binding site for residue SO4 A 706 |
| Chain | Residue |
| A | LYS476 |
| A | SER515 |
| A | GLU516 |
| A | LEU517 |
| site_id | AC7 |
| Number of Residues | 5 |
| Details | binding site for residue EDO B 501 |
| Chain | Residue |
| B | VAL75 |
| B | PHE77 |
| B | GLY152 |
| B | TRP410 |
| B | ILE411 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 190 |
| Details | Domain: {"description":"Reverse transcriptase","evidences":[{"source":"PROSITE-ProRule","id":"PRU00405","evidenceCode":"ECO:0000255"}]} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 16 |
| Details | Region: {"description":"RT 'primer grip'"} |
| site_id | SWS_FT_FI3 |
| Number of Residues | 32 |
| Details | Motif: {"description":"Tryptophan repeat motif"} |
| site_id | SWS_FT_FI4 |
| Number of Residues | 6 |
| Details | Binding site: {} |
| site_id | SWS_FT_FI5 |
| Number of Residues | 4 |
| Details | Binding site: {"evidences":[{"evidenceCode":"ECO:0000305"}]} |
| site_id | SWS_FT_FI6 |
| Number of Residues | 4 |
| Details | Site: {"description":"Essential for RT p66/p51 heterodimerization"} |
| site_id | SWS_FT_FI7 |
| Number of Residues | 1 |
| Details | Site: {"description":"Cleavage; by viral protease; partial"} |
