6EKP

Tryptophan Repressor TrpR from E.coli variant T44L T81M S88Y with Indole-3-acetic acid as ligand

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003676	molecular_function	nucleic acid binding
A	0003677	molecular_function	DNA binding
A	0003700	molecular_function	DNA-binding transcription factor activity
A	0005737	cellular_component	cytoplasm
A	0006351	biological_process	DNA-templated transcription
A	0006355	biological_process	regulation of DNA-templated transcription
A	0043565	molecular_function	sequence-specific DNA binding
A	0045892	biological_process	negative regulation of DNA-templated transcription
B	0003676	molecular_function	nucleic acid binding
B	0003677	molecular_function	DNA binding
B	0003700	molecular_function	DNA-binding transcription factor activity
B	0005737	cellular_component	cytoplasm
B	0006351	biological_process	DNA-templated transcription
B	0006355	biological_process	regulation of DNA-templated transcription
B	0043565	molecular_function	sequence-specific DNA binding
B	0045892	biological_process	negative regulation of DNA-templated transcription

Functional Information from PDB Data

site_id	AC1
Number of Residues	6
Details	binding site for residue IAC A 201

Chain	Residue
A	ARG54
A	ARG84
A	TYR88
A	HOH326
B	LEU41
B	MET42

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site_id	AC2
Number of Residues	9
Details	binding site for residue P3G A 202

Chain	Residue
A	ARG54
A	HOH387
B	ASP46
B	GLU47
B	ALA50
B	ARG54
A	ASP46
A	GLU47
A	ALA50

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site_id	AC3
Number of Residues	6
Details	binding site for residue IAC B 201

Chain	Residue
A	LEU41
A	MET42
B	ARG54
B	ARG84
B	TYR88
B	HOH329

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	46
Details	DNA binding: {}

Chain

Residue

Details

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