6EKP
Tryptophan Repressor TrpR from E.coli variant T44L T81M S88Y with Indole-3-acetic acid as ligand
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003677 | molecular_function | DNA binding |
| A | 0003700 | molecular_function | DNA-binding transcription factor activity |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0006355 | biological_process | regulation of DNA-templated transcription |
| A | 0043565 | molecular_function | sequence-specific DNA binding |
| A | 0045892 | biological_process | negative regulation of DNA-templated transcription |
| B | 0003677 | molecular_function | DNA binding |
| B | 0003700 | molecular_function | DNA-binding transcription factor activity |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0006355 | biological_process | regulation of DNA-templated transcription |
| B | 0043565 | molecular_function | sequence-specific DNA binding |
| B | 0045892 | biological_process | negative regulation of DNA-templated transcription |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 6 |
| Details | binding site for residue IAC A 201 |
| Chain | Residue |
| A | ARG54 |
| A | ARG84 |
| A | TYR88 |
| A | HOH326 |
| B | LEU41 |
| B | MET42 |
| site_id | AC2 |
| Number of Residues | 9 |
| Details | binding site for residue P3G A 202 |
| Chain | Residue |
| A | ARG54 |
| A | HOH387 |
| B | ASP46 |
| B | GLU47 |
| B | ALA50 |
| B | ARG54 |
| A | ASP46 |
| A | GLU47 |
| A | ALA50 |
| site_id | AC3 |
| Number of Residues | 6 |
| Details | binding site for residue IAC B 201 |
| Chain | Residue |
| A | LEU41 |
| A | MET42 |
| B | ARG54 |
| B | ARG84 |
| B | TYR88 |
| B | HOH329 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 46 |
| Details | DNA_BIND: |
| Chain | Residue | Details |
| A | GLN68-ALA91 | |
| B | GLN68-ALA91 |
