6EIY
Crystal structure of KDM5B in complex with KDOPZ000034a.
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 4 |
| Details | binding site for residue ZN A 801 |
| Chain | Residue |
| A | CYS692 |
| A | CYS695 |
| A | CYS715 |
| A | HIS718 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | binding site for residue MN A 802 |
| Chain | Residue |
| A | LEU90 |
| A | ASN91 |
| A | LEU413 |
| A | THR416 |
| A | GLU419 |
| site_id | AC3 |
| Number of Residues | 6 |
| Details | binding site for residue EDO A 803 |
| Chain | Residue |
| A | ASP630 |
| A | CYS699 |
| A | PHE700 |
| A | MET701 |
| A | SER702 |
| A | HOH936 |
| site_id | AC4 |
| Number of Residues | 3 |
| Details | binding site for residue EDO A 804 |
| Chain | Residue |
| A | GLY524 |
| A | TYR525 |
| A | ARG584 |
| site_id | AC5 |
| Number of Residues | 6 |
| Details | binding site for residue EDO A 805 |
| Chain | Residue |
| A | PHE83 |
| A | GLY426 |
| A | ALA427 |
| A | ASP428 |
| A | LEU487 |
| A | VAL489 |
| site_id | AC6 |
| Number of Residues | 7 |
| Details | binding site for residue DMS A 806 |
| Chain | Residue |
| A | ILE500 |
| A | TRP504 |
| A | HIS617 |
| A | TYR618 |
| A | LEU621 |
| A | ARG623 |
| A | HOH983 |
| site_id | AC7 |
| Number of Residues | 7 |
| Details | binding site for residue DMS A 807 |
| Chain | Residue |
| A | TRP486 |
| A | TYR488 |
| A | SER507 |
| A | ALA599 |
| A | VAL600 |
| A | ASN601 |
| A | HOH995 |
| site_id | AC8 |
| Number of Residues | 3 |
| Details | binding site for residue DMS A 808 |
| Chain | Residue |
| A | HIS622 |
| A | HIS718 |
| A | HOH998 |
| site_id | AC9 |
| Number of Residues | 6 |
| Details | binding site for residue MN A 809 |
| Chain | Residue |
| A | HIS499 |
| A | GLU501 |
| A | HIS587 |
| A | B6W810 |
| A | HOH965 |
| A | HOH995 |
| site_id | AD1 |
| Number of Residues | 18 |
| Details | binding site for residue B6W A 810 |
| Chain | Residue |
| A | GLN88 |
| A | GLN96 |
| A | THR97 |
| A | TYR425 |
| A | GLY426 |
| A | TYR488 |
| A | SER495 |
| A | PHE496 |
| A | CYS497 |
| A | HIS499 |
| A | ASN509 |
| A | LYS517 |
| A | HIS587 |
| A | ASN591 |
| A | MN809 |
| A | HOH965 |
| A | HOH995 |
| A | HOH1037 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 41 |
| Details | Domain: {"description":"JmjN","evidences":[{"source":"PROSITE-ProRule","id":"PRU00537","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 166 |
| Details | Domain: {"description":"JmjC","evidences":[{"source":"PROSITE-ProRule","id":"PRU00538","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 52 |
| Details | Zinc finger: {"description":"C5HC2","evidences":[{"source":"PubMed","id":"26741168","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"27214403","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"28262558","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 4 |
| Details | Binding site: {"evidences":[{"source":"UniProtKB","id":"P29375","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 3 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"26741168","evidenceCode":"ECO:0000305"},{"source":"PubMed","id":"27214403","evidenceCode":"ECO:0000305"},{"source":"PubMed","id":"28262558","evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
