6EIN
Crystal structure of KDM5B in complex with S49365a.
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 13 |
| Details | binding site for residue B7Z A 801 |
| Chain | Residue |
| A | TYR425 |
| A | TRP519 |
| A | HIS587 |
| A | MN803 |
| A | HOH975 |
| A | ASP428 |
| A | CYS480 |
| A | GLY481 |
| A | TYR488 |
| A | PHE496 |
| A | HIS499 |
| A | GLU501 |
| A | LYS517 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | binding site for residue ZN A 802 |
| Chain | Residue |
| A | CYS692 |
| A | CYS695 |
| A | CYS715 |
| A | HIS718 |
| site_id | AC3 |
| Number of Residues | 5 |
| Details | binding site for residue MN A 803 |
| Chain | Residue |
| A | HIS499 |
| A | GLU501 |
| A | HIS587 |
| A | B7Z801 |
| A | HOH975 |
| site_id | AC4 |
| Number of Residues | 2 |
| Details | binding site for residue MN A 804 |
| Chain | Residue |
| A | HIS622 |
| A | HOH1074 |
| site_id | AC5 |
| Number of Residues | 7 |
| Details | binding site for residue EDO A 805 |
| Chain | Residue |
| A | PRO465 |
| A | SER470 |
| A | LEU472 |
| A | MET482 |
| A | ASN601 |
| A | PHE602 |
| A | CYS603 |
| site_id | AC6 |
| Number of Residues | 5 |
| Details | binding site for residue EDO A 806 |
| Chain | Residue |
| A | ILE500 |
| A | TRP504 |
| A | ARG584 |
| A | HIS617 |
| A | ARG623 |
| site_id | AC7 |
| Number of Residues | 5 |
| Details | binding site for residue EDO A 807 |
| Chain | Residue |
| A | ARG612 |
| A | ASP630 |
| A | MET658 |
| A | GLU662 |
| A | HOH1055 |
| site_id | AC8 |
| Number of Residues | 4 |
| Details | binding site for residue EDO A 808 |
| Chain | Residue |
| A | ARG670 |
| A | VAL674 |
| A | ILE675 |
| A | HOH982 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 41 |
| Details | Domain: {"description":"JmjN","evidences":[{"source":"PROSITE-ProRule","id":"PRU00537","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 52 |
| Details | Zinc finger: {"description":"C5HC2","evidences":[{"source":"PubMed","id":"26741168","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"27214403","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"28262558","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 4 |
| Details | Binding site: {"evidences":[{"source":"UniProtKB","id":"P29375","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 3 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"26741168","evidenceCode":"ECO:0000305"},{"source":"PubMed","id":"27214403","evidenceCode":"ECO:0000305"},{"source":"PubMed","id":"28262558","evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
