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6EF4

Crystal structure of mouse PP2A Aalpha P179R mutant

Functional Information from GO Data
ChainGOidnamespacecontents
A0000159cellular_componentprotein phosphatase type 2A complex
A0000775cellular_componentchromosome, centromeric region
A0004722molecular_functionprotein serine/threonine phosphatase activity
A0005515molecular_functionprotein binding
A0005634cellular_componentnucleus
A0005694cellular_componentchromosome
A0005737cellular_componentcytoplasm
A0005829cellular_componentcytosol
A0005886cellular_componentplasma membrane
A0007059biological_processchromosome segregation
A0007143biological_processfemale meiotic nuclear division
A0016328cellular_componentlateral plasma membrane
A0030425cellular_componentdendrite
A0035331biological_processnegative regulation of hippo signaling
A0042995cellular_componentcell projection
A0043005cellular_componentneuron projection
A0043025cellular_componentneuronal cell body
A0043029biological_processT cell homeostasis
A0045202cellular_componentsynapse
A0046982molecular_functionprotein heterodimerization activity
A0051232biological_processmeiotic spindle elongation
A0051306biological_processmitotic sister chromatid separation
A0051754biological_processmeiotic sister chromatid cohesion, centromeric
A0051898biological_processnegative regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction
A0090443cellular_componentFAR/SIN/STRIPAK complex
A0098978cellular_componentglutamatergic synapse
A1903538biological_processregulation of meiotic cell cycle process involved in oocyte maturation
A1990405molecular_functionprotein antigen binding
A2001241biological_processpositive regulation of extrinsic apoptotic signaling pathway in absence of ligand
Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues1
DetailsMOD_RES: N-acetylalanine => ECO:0000250|UniProtKB:P30153
ChainResidueDetails
AALA2

site_idSWS_FT_FI2
Number of Residues1
DetailsMOD_RES: N6-acetyllysine => ECO:0007744|PubMed:23806337
ChainResidueDetails
ALYS280

224931

PDB entries from 2024-09-11

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