6EEV

Structure of class II HMG-CoA reductase from Delftia acidovorans with mevalonate bound

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000166	molecular_function	nucleotide binding
A	0004420	molecular_function	hydroxymethylglutaryl-CoA reductase (NADPH) activity
A	0015936	biological_process	coenzyme A metabolic process
A	0016491	molecular_function	oxidoreductase activity
A	0016616	molecular_function	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
A	0140643	molecular_function	hydroxymethylglutaryl-CoA reductase (NADH) activity

Functional Information from PROSITE/UniProt

site_id	PS00066
Number of Residues	15
Details	HMG_COA_REDUCTASE_1 Hydroxymethylglutaryl-coenzyme A reductases signature 1. HlIVdVRDaMGaNtV

Chain	Residue	Details
A	HIS176-VAL190

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site_id	PS00318
Number of Residues	8
Details	HMG_COA_REDUCTASE_2 Hydroxymethylglutaryl-coenzyme A reductases signature 2. VGlVGGAT

Chain	Residue	Details
A	VAL325-THR332

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site_id	PS01192
Number of Residues	14
Details	HMG_COA_REDUCTASE_3 Hydroxymethylglutaryl-coenzyme A reductases signature 3. ALaTegIqRGHMaL

Chain	Residue	Details
A	ALA371-LEU384

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