6E93

Crystal Structure of ZBTB38 C-terminal Zinc Fingers 6-9 in complex with methylated DNA

Functional Information from PDB Data

site_id	AC1
Number of Residues	4
Details	binding site for residue ZN A 1201

Chain	Residue
A	CYS1068
A	CYS1071
A	HIS1084
A	HIS1088

---

site_id	AC2
Number of Residues	4
Details	binding site for residue ZN A 1202

Chain	Residue
A	CYS1040
A	CYS1043
A	HIS1056
A	HIS1060

---

site_id	AC3
Number of Residues	4
Details	binding site for residue ZN A 1203

Chain	Residue
A	CYS1099
A	HIS1112
A	HIS1116
A	CYS1096

---

site_id	AC4
Number of Residues	4
Details	binding site for residue ZN A 1204

Chain	Residue
A	CYS1012
A	CYS1015
A	HIS1028
A	HIS1032

---

Functional Information from PROSITE/UniProt

site_id	PS00028
Number of Residues	21
Details	ZINC_FINGER_C2H2_1 Zinc finger C2H2 type domain signature. Cel..CakqFqspstlkmHmrc..H

Chain	Residue	Details
A	CYS1012-HIS1032
A	CYS1040-HIS1060
A	CYS1068-HIS1088
A	CYS1096-HIS1116

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	22
Details	ZN_FING: C2H2-type 6 => ECO:0000255|PROSITE-ProRule:PRU00042

Chain	Residue	Details
A	TYR1010-HIS1032

---

site_id	SWS_FT_FI2
Number of Residues	22
Details	ZN_FING: C2H2-type 7 => ECO:0000255|PROSITE-ProRule:PRU00042

Chain	Residue	Details
A	TYR1038-HIS1060

---

site_id	SWS_FT_FI3
Number of Residues	22
Details	ZN_FING: C2H2-type 8 => ECO:0000255|PROSITE-ProRule:PRU00042

Chain	Residue	Details
A	PHE1066-HIS1088

---

site_id	SWS_FT_FI4
Number of Residues	22
Details	ZN_FING: C2H2-type 9 => ECO:0000255|PROSITE-ProRule:PRU00042

Chain	Residue	Details
A	TYR1094-HIS1116

---

site_id	SWS_FT_FI5
Number of Residues	4
Details	CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2) => ECO:0007744|PubMed:28112733

Chain	Residue	Details
A	LYS1017
A	LYS1026
A	LYS1109

---