6E7F

Crystal Structure of Human Inositol Polyphosphate Multikinase (IPMK) Catalytic Core Domain

Replaces:  6C8A

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0016301	molecular_function	kinase activity
A	0032958	biological_process	inositol phosphate biosynthetic process
B	0016301	molecular_function	kinase activity
B	0032958	biological_process	inositol phosphate biosynthetic process

Functional Information from PDB Data

site_id	AC1
Number of Residues	5
Details	binding site for residue SO4 A 501

Chain	Residue
A	THR121
A	ALA122
A	ASP125
B	PRO84
B	SO4502

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site_id	AC2
Number of Residues	5
Details	binding site for residue SO4 B 501

Chain	Residue
B	HOH606
A	HIS-13
A	HIS-12
B	ASP97
B	HOH605

---

site_id	AC3
Number of Residues	5
Details	binding site for residue SO4 B 502

Chain	Residue
A	TYR127
A	SO4501
B	PRO84
B	LEU87
B	GLU88

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	18
Details	Binding site: {"evidences":[{"source":"PubMed","id":"28882892","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"5W2H","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5W2I","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI2
Number of Residues	14
Details	Binding site: {"evidences":[{"source":"PubMed","id":"28882892","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"5W2H","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

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