6E3T

Crystal Structure of the Heterodimeric HIF-2 Complex with Antagonist T1001

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003700	molecular_function	DNA-binding transcription factor activity
A	0005634	cellular_component	nucleus
A	0005667	cellular_component	transcription regulator complex
A	0005737	cellular_component	cytoplasm
A	0006355	biological_process	regulation of DNA-templated transcription
A	0046983	molecular_function	protein dimerization activity
B	0003700	molecular_function	DNA-binding transcription factor activity
B	0005634	cellular_component	nucleus
B	0005667	cellular_component	transcription regulator complex
B	0005737	cellular_component	cytoplasm
B	0006355	biological_process	regulation of DNA-templated transcription
B	0046983	molecular_function	protein dimerization activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	11
Details	binding site for residue HO7 B 401

Chain	Residue
B	PHE244
B	CYS339
B	ASN341
B	HIS248
B	ALA277
B	TYR281
B	VAL302
B	TYR307
B	MET309
B	LEU319
B	THR321

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