6E2B

Ubiquitin in complex with Pt(2-phenilpyridine)(PPh3)

Functional Information from PDB Data

site_id	AC1
Number of Residues	8
Details	binding site for residue SO4 A 101

Chain	Residue
A	ARG72
A	ARG74
A	GLY75
A	HOH213
A	HOH228
C	LYS6
C	HOH218
C	HOH245

---

site_id	AC2
Number of Residues	8
Details	binding site for residue SO4 A 102

Chain	Residue
A	GLN49
A	ARG72
A	HOH220
A	HOH230
A	HOH264
C	LYS6
C	HIS68
A	ARG42

---

site_id	AC3
Number of Residues	6
Details	binding site for residue GOL A 103

Chain	Residue
A	SER65
A	THR66
A	HOH203
A	HOH229
A	HOH245
A	HOH274

---

site_id	AC4
Number of Residues	6
Details	binding site for residue GOL A 104

Chain	Residue
A	LYS48
A	ARG54
A	HOH212
A	HOH216
A	HOH252
A	HOH262

---

site_id	AC5
Number of Residues	14
Details	binding site for residue PT7 A 105

Chain	Residue
A	LYS6
A	THR7
A	LEU8
A	ILE44
A	ALA46
A	GLY47
A	HIS68
A	LEU69
C	PT7103
I	THR9
P	GLY47
P	GLN49
P	VAL70
P	PT7104

---

site_id	AC6
Number of Residues	9
Details	binding site for residue GOL C 101

Chain	Residue
C	ARG42
C	GLN49
C	ARG72
C	GOL102
C	GOL104
E	LYS11
E	HOH202
P	HIS68
P	PT7104

---

site_id	AC7
Number of Residues	13
Details	binding site for residue GOL C 102

Chain	Residue
C	ARG42
C	GLN49
C	GLU51
C	ARG72
C	GOL101
C	GOL104
C	HOH223
C	HOH224
C	HOH238
P	LYS6
P	THR66
P	HIS68
P	HOH209

---

site_id	AC8
Number of Residues	14
Details	binding site for residue PT7 C 103

Chain	Residue
A	GLY47
A	GLN49
A	VAL70
A	PT7105
C	LYS6
C	THR7
C	LEU8
C	ILE44
C	ALA46
C	GLY47
C	HIS68
E	THR9
G	THR9
P	PT7104

---

site_id	AC9
Number of Residues	8
Details	binding site for residue GOL C 104

Chain	Residue
C	ARG72
C	ARG74
C	GLY75
C	GOL101
C	GOL102
E	LYS11
P	GLN31
P	HOH237

---

site_id	AD1
Number of Residues	10
Details	binding site for residue GOL E 101

Chain	Residue
E	ILE44
E	ALA46
E	GLY47
E	HIS68
E	HOH216
G	ALA46
G	HIS68
G	HOH101
I	HIS68
I	GOL102

---

site_id	AD2
Number of Residues	11
Details	binding site for residue SO4 I 101

Chain	Residue
G	HIS68
I	LYS6
I	HIS68
I	GOL102
I	HOH201
I	HOH202
I	HOH238
I	HOH246
E	LYS6
E	HIS68
G	LYS6

---

site_id	AD3
Number of Residues	10
Details	binding site for residue GOL I 102

Chain	Residue
E	THR66
E	HIS68
E	GOL101
I	ILE44
I	ALA46
I	GLY47
I	HIS68
I	SO4101
I	HOH211
I	HOH217

---

site_id	AD4
Number of Residues	4
Details	binding site for residue GOL I 103

Chain	Residue
I	LYS48
I	ARG54
I	HOH212
I	HOH213

---

site_id	AD5
Number of Residues	10
Details	binding site for residue SO4 P 101

Chain	Residue
A	LYS6
A	THR66
A	HIS68
P	ARG42
P	GLN49
P	ARG72
P	HOH201
P	HOH216
P	HOH226
P	HOH238

---

site_id	AD6
Number of Residues	5
Details	binding site for residue SO4 P 102

Chain	Residue
P	LYS48
P	ARG54
P	HOH202
P	HOH210
P	HOH227

---

site_id	AD7
Number of Residues	9
Details	binding site for residue SO4 P 103

Chain	Residue
A	LYS6
A	HOH204
A	HOH211
P	ARG72
P	ARG74
P	GLY75
P	HOH201
P	HOH231
P	HOH251

---

site_id	AD8
Number of Residues	14
Details	binding site for residue PT7 P 104

Chain	Residue
A	PT7105
C	GLY47
C	GOL101
C	PT7103
E	THR9
P	LYS6
P	THR7
P	LEU8
P	ILE44
P	ALA46
P	GLY47
P	HIS68
P	LEU69
P	VAL70

---

Functional Information from PROSITE/UniProt

site_id	PS00299
Number of Residues	26
Details	UBIQUITIN_1 Ubiquitin domain signature. KakIqDkegIPpdqQrLIFaGkqleD

Chain	Residue	Details
A	LYS27-ASP52

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	12
Details	SITE: Interacts with activating enzyme

Chain	Residue	Details
A	ARG54
I	ARG72
P	ARG54
P	ARG72
A	ARG72
C	ARG54
C	ARG72
E	ARG54
E	ARG72
G	ARG54
G	ARG72
I	ARG54

---

site_id	SWS_FT_FI2
Number of Residues	6
Details	SITE: Essential for function

Chain	Residue	Details
A	HIS68
C	HIS68
E	HIS68
G	HIS68
I	HIS68
P	HIS68

---

site_id	SWS_FT_FI3
Number of Residues	6
Details	MOD_RES: Phosphoserine; by PINK1 => ECO:0000250|UniProtKB:P62979

Chain	Residue	Details
A	SER65
C	SER65
E	SER65
G	SER65
I	SER65
P	SER65

---

site_id	SWS_FT_FI4
Number of Residues	6
Details	MOD_RES: ADP-ribosylglycine => ECO:0000250|UniProtKB:P62979

Chain	Residue	Details
A	GLY76
C	GLY76
E	GLY76
G	GLY76
I	GLY76
P	GLY76

---

site_id	SWS_FT_FI5
Number of Residues	42
Details	CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin) => ECO:0000250|UniProtKB:P62979

Chain	Residue	Details
A	LYS6
C	LYS27
C	LYS29
C	LYS33
C	LYS48
C	LYS63
E	LYS6
E	LYS11
E	LYS27
E	LYS29
E	LYS33
A	LYS11
E	LYS48
E	LYS63
G	LYS6
G	LYS11
G	LYS27
G	LYS29
G	LYS33
G	LYS48
G	LYS63
I	LYS6
A	LYS27
I	LYS11
I	LYS27
I	LYS29
I	LYS33
I	LYS48
I	LYS63
P	LYS6
P	LYS11
P	LYS27
P	LYS29
A	LYS29
P	LYS33
P	LYS48
P	LYS63
A	LYS33
A	LYS48
A	LYS63
C	LYS6
C	LYS11

---

site_id	SWS_FT_FI6
Number of Residues	12
Details	CROSSLNK: Glycyl lysine isopeptide (Gly-Lys) (interchain with K-? in acceptor proteins)

Chain	Residue	Details
I	GLY76
P	GLY76
A	GLY76
C	GLY76
E	GLY76
G	GLY76

---