Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 12 |
| Details | binding site for residue SR A 901 |
| Chain | Residue |
| A | HOH1150 |
| A | HOH1323 |
| A | HOH1323 |
| A | HOH1323 |
| A | HOH1150 |
| A | HOH1150 |
| A | HOH1174 |
| A | HOH1174 |
| A | HOH1174 |
| A | HOH1221 |
| A | HOH1221 |
| A | HOH1221 |
| site_id | AC2 |
| Number of Residues | 8 |
| Details | binding site for residue SR A 902 |
| Chain | Residue |
| A | ASN467 |
| A | ASP499 |
| A | HOH1024 |
| A | HOH1115 |
| A | HOH1313 |
| A | HOH1643 |
| A | HOH1667 |
| A | HOH1678 |
| site_id | AC3 |
| Number of Residues | 7 |
| Details | binding site for residue SR A 903 |
| Chain | Residue |
| A | ALA777 |
| A | HOH1060 |
| A | HOH1064 |
| A | HOH1259 |
| A | HOH1429 |
| A | HOH1551 |
| A | HOH1950 |
| site_id | AC4 |
| Number of Residues | 5 |
| Details | binding site for residue SR A 904 |
| Chain | Residue |
| A | SR906 |
| A | HOH1194 |
| A | HOH1251 |
| A | HOH1307 |
| A | HOH1477 |
| site_id | AC5 |
| Number of Residues | 5 |
| Details | binding site for residue SR A 905 |
| Chain | Residue |
| A | SR906 |
| A | HOH1029 |
| A | HOH1081 |
| A | HOH1883 |
| A | HOH1955 |
| site_id | AC6 |
| Number of Residues | 6 |
| Details | binding site for residue SR A 906 |
| Chain | Residue |
| A | SR904 |
| A | SR905 |
| A | HOH1268 |
| A | HOH1307 |
| A | HOH1336 |
| A | HOH1477 |
| site_id | AC7 |
| Number of Residues | 6 |
| Details | binding site for residue SR A 907 |
| Chain | Residue |
| A | HOH1044 |
| A | HOH1347 |
| A | HOH1623 |
| A | HOH1783 |
| A | HOH1814 |
| A | HOH1917 |
| site_id | AC8 |
| Number of Residues | 3 |
| Details | binding site for residue CL A 908 |
| Chain | Residue |
| A | VAL435 |
| A | GLY533 |
| A | TYR610 |
| site_id | AC9 |
| Number of Residues | 3 |
| Details | binding site for residue CL A 909 |
| Chain | Residue |
| A | LYS699 |
| A | LYS699 |
| A | LYS699 |
| site_id | AD1 |
| Number of Residues | 2 |
| Details | binding site for residue CL A 910 |
| Chain | Residue |
| A | ARG457 |
| A | THR489 |
| site_id | AD2 |
| Number of Residues | 5 |
| Details | binding site for residue GOL A 911 |
| Chain | Residue |
| A | TYR433 |
| A | HIS461 |
| A | GLU463 |
| A | HOH1159 |
| A | HOH1396 |
| site_id | AD3 |
| Number of Residues | 7 |
| Details | binding site for residue GOL A 912 |
| Chain | Residue |
| A | GLY602 |
| A | GLU603 |
| A | GLY604 |
| A | HOH1004 |
| A | HOH1170 |
| A | HOH1390 |
| C | SER770 |
| site_id | AD4 |
| Number of Residues | 10 |
| Details | binding site for residue GOL A 913 |
| Chain | Residue |
| A | ASN262 |
| A | ASP268 |
| A | LYS269 |
| A | ARG283 |
| A | GLY287 |
| A | THR288 |
| A | HOH1014 |
| A | HOH1028 |
| A | HOH1063 |
| A | HOH1367 |
| site_id | AD5 |
| Number of Residues | 6 |
| Details | binding site for residue EDO A 914 |
| Chain | Residue |
| A | ASP439 |
| A | ARG444 |
| A | ASN467 |
| A | TYR508 |
| A | HOH1121 |
| A | HOH1420 |
| site_id | AD6 |
| Number of Residues | 4 |
| Details | binding site for residue EDO A 915 |
| Chain | Residue |
| A | SER770 |
| A | TYR772 |
| A | HOH1019 |
| A | HOH1705 |
| site_id | AD7 |
| Number of Residues | 12 |
| Details | binding site for residue SR B 901 |
| Chain | Residue |
| B | HOH1586 |
| B | HOH1586 |
| B | HOH1154 |
| B | HOH1154 |
| B | HOH1154 |
| B | HOH1259 |
| B | HOH1259 |
| B | HOH1259 |
| B | HOH1473 |
| B | HOH1473 |
| B | HOH1473 |
| B | HOH1586 |
| site_id | AD8 |
| Number of Residues | 7 |
| Details | binding site for residue SR B 902 |
| Chain | Residue |
| B | ASN467 |
| B | HOH1034 |
| B | HOH1059 |
| B | HOH1173 |
| B | HOH1561 |
| B | HOH1623 |
| B | HOH1673 |
| site_id | AD9 |
| Number of Residues | 8 |
| Details | binding site for residue SR B 903 |
| Chain | Residue |
| B | ALA777 |
| B | HOH1044 |
| B | HOH1178 |
| B | HOH1249 |
| B | HOH1310 |
| B | HOH1491 |
| B | HOH1871 |
| B | HOH1875 |
| site_id | AE1 |
| Number of Residues | 6 |
| Details | binding site for residue SR B 904 |
| Chain | Residue |
| A | HOH1962 |
| B | SR908 |
| B | HOH1045 |
| B | HOH1098 |
| B | HOH1314 |
| B | HOH1441 |
| site_id | AE2 |
| Number of Residues | 2 |
| Details | binding site for residue SR B 905 |
| Chain | Residue |
| B | HOH1166 |
| B | HOH1204 |
| site_id | AE3 |
| Number of Residues | 5 |
| Details | binding site for residue SR B 906 |
| Chain | Residue |
| B | EDO916 |
| B | HOH1003 |
| B | HOH1062 |
| B | HOH1238 |
| B | HOH1842 |
| site_id | AE4 |
| Number of Residues | 6 |
| Details | binding site for residue SR B 907 |
| Chain | Residue |
| A | HOH1561 |
| A | HOH1600 |
| B | GLU369 |
| B | SR909 |
| B | HOH1146 |
| B | HOH1469 |
| site_id | AE5 |
| Number of Residues | 6 |
| Details | binding site for residue SR B 908 |
| Chain | Residue |
| A | HOH1962 |
| B | SR904 |
| B | HOH1163 |
| B | HOH1286 |
| B | HOH1441 |
| B | HOH1877 |
| site_id | AE6 |
| Number of Residues | 3 |
| Details | binding site for residue SR B 909 |
| Chain | Residue |
| A | HOH1600 |
| B | SR907 |
| B | HOH1146 |
| site_id | AE7 |
| Number of Residues | 3 |
| Details | binding site for residue CL B 910 |
| Chain | Residue |
| B | LYS699 |
| B | LYS699 |
| B | LYS699 |
| site_id | AE8 |
| Number of Residues | 2 |
| Details | binding site for residue CL B 911 |
| Chain | Residue |
| B | THR489 |
| B | ARG518 |
| site_id | AE9 |
| Number of Residues | 5 |
| Details | binding site for residue CL B 912 |
| Chain | Residue |
| B | VAL435 |
| B | GLY533 |
| B | PRO534 |
| B | TYR610 |
| B | HOH1731 |
| site_id | AF1 |
| Number of Residues | 5 |
| Details | binding site for residue GOL B 913 |
| Chain | Residue |
| B | TYR360 |
| B | GLN365 |
| B | TRP421 |
| B | HOH1120 |
| B | HOH1403 |
| site_id | AF2 |
| Number of Residues | 11 |
| Details | binding site for residue GOL B 914 |
| Chain | Residue |
| B | TYR433 |
| B | HIS461 |
| B | GLU463 |
| B | TYR495 |
| B | VAL526 |
| B | HOH1066 |
| B | HOH1080 |
| B | HOH1252 |
| B | HOH1332 |
| B | HOH1467 |
| B | HOH1519 |
| site_id | AF3 |
| Number of Residues | 11 |
| Details | binding site for residue GOL B 915 |
| Chain | Residue |
| B | ASN262 |
| B | ASP268 |
| B | LYS269 |
| B | ARG283 |
| B | GLY287 |
| B | THR288 |
| B | HOH1012 |
| B | HOH1021 |
| B | HOH1073 |
| B | HOH1322 |
| B | HOH1485 |
| site_id | AF4 |
| Number of Residues | 6 |
| Details | binding site for residue EDO B 916 |
| Chain | Residue |
| B | VAL435 |
| B | ASP436 |
| B | SR906 |
| B | HOH1003 |
| B | HOH1019 |
| B | HOH1285 |
| site_id | AF5 |
| Number of Residues | 7 |
| Details | binding site for residue EDO B 917 |
| Chain | Residue |
| B | ASP641 |
| B | ARG662 |
| B | PRO664 |
| B | LEU666 |
| B | ARG684 |
| B | HOH1037 |
| B | HOH1195 |
| site_id | AF6 |
| Number of Residues | 6 |
| Details | binding site for residue EDO B 918 |
| Chain | Residue |
| B | ALA752 |
| B | ASN753 |
| B | GLY754 |
| B | THR782 |
| B | HOH1040 |
| B | HOH1554 |
| site_id | AF7 |
| Number of Residues | 12 |
| Details | binding site for residue SR C 901 |
| Chain | Residue |
| C | HOH1127 |
| C | HOH1127 |
| C | HOH1127 |
| C | HOH1162 |
| C | HOH1162 |
| C | HOH1162 |
| C | HOH1178 |
| C | HOH1178 |
| C | HOH1178 |
| C | HOH1515 |
| C | HOH1515 |
| C | HOH1515 |
| site_id | AF8 |
| Number of Residues | 8 |
| Details | binding site for residue SR C 902 |
| Chain | Residue |
| C | ASN467 |
| C | ASP499 |
| C | HOH1008 |
| C | HOH1123 |
| C | HOH1179 |
| C | HOH1375 |
| C | HOH1514 |
| C | HOH1558 |
| site_id | AF9 |
| Number of Residues | 6 |
| Details | binding site for residue SR C 903 |
| Chain | Residue |
| C | ASN259 |
| C | ASN262 |
| C | HOH1148 |
| C | HOH1439 |
| C | HOH1476 |
| C | HOH1532 |
| site_id | AG1 |
| Number of Residues | 6 |
| Details | binding site for residue SR C 904 |
| Chain | Residue |
| C | HOH1090 |
| C | HOH1093 |
| C | HOH1263 |
| C | HOH1355 |
| C | HOH1640 |
| C | HOH1732 |
| site_id | AG2 |
| Number of Residues | 4 |
| Details | binding site for residue SR C 905 |
| Chain | Residue |
| A | HOH1011 |
| A | HOH1090 |
| A | HOH1652 |
| C | HOH1611 |
| site_id | AG3 |
| Number of Residues | 5 |
| Details | binding site for residue SR C 906 |
| Chain | Residue |
| C | EDO915 |
| C | HOH1138 |
| C | HOH1459 |
| C | HOH1540 |
| C | HOH1719 |
| site_id | AG4 |
| Number of Residues | 6 |
| Details | binding site for residue SR C 907 |
| Chain | Residue |
| C | GLY486 |
| C | HOH1064 |
| C | HOH1260 |
| C | HOH1495 |
| C | HOH1595 |
| C | HOH1614 |
| site_id | AG5 |
| Number of Residues | 4 |
| Details | binding site for residue SR C 908 |
| Chain | Residue |
| C | ALA777 |
| C | ASP778 |
| C | HOH1134 |
| C | HOH1329 |
| site_id | AG6 |
| Number of Residues | 3 |
| Details | binding site for residue CL C 909 |
| Chain | Residue |
| C | LYS699 |
| C | LYS699 |
| C | LYS699 |
| site_id | AG7 |
| Number of Residues | 2 |
| Details | binding site for residue CL C 910 |
| Chain | Residue |
| C | GLY533 |
| C | TYR610 |
| site_id | AG8 |
| Number of Residues | 4 |
| Details | binding site for residue CL C 911 |
| Chain | Residue |
| C | ARG457 |
| C | THR489 |
| C | ARG518 |
| C | HOH1596 |
| site_id | AG9 |
| Number of Residues | 10 |
| Details | binding site for residue GOL C 912 |
| Chain | Residue |
| C | THR640 |
| C | ASP641 |
| C | THR654 |
| C | ARG662 |
| C | PRO664 |
| C | VAL665 |
| C | LEU666 |
| C | HOH1020 |
| C | HOH1035 |
| C | HOH1186 |
| site_id | AH1 |
| Number of Residues | 7 |
| Details | binding site for residue GOL C 913 |
| Chain | Residue |
| C | HIS461 |
| C | TYR495 |
| C | HOH1106 |
| C | HOH1248 |
| C | HOH1260 |
| C | HOH1264 |
| C | HOH1277 |
| site_id | AH2 |
| Number of Residues | 2 |
| Details | binding site for residue EDO C 914 |
| Chain | Residue |
| C | GLY529 |
| C | EDO916 |
| site_id | AH3 |
| Number of Residues | 7 |
| Details | binding site for residue EDO C 915 |
| Chain | Residue |
| C | GLU390 |
| C | ASN392 |
| C | ALA428 |
| C | HIS461 |
| C | GLU463 |
| C | SR906 |
| C | HOH1106 |
| site_id | AH4 |
| Number of Residues | 6 |
| Details | binding site for residue EDO C 916 |
| Chain | Residue |
| C | ARG530 |
| C | TYR531 |
| C | EDO914 |
| C | HOH1341 |
| C | HOH1344 |
| C | HOH1566 |
