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6DWU

Crystal structure of complex of BBKI and Bovine Trypsin

This is a non-PDB format compatible entry.
Functional Information from GO Data
ChainGOidnamespacecontents
AA0004175molecular_functionendopeptidase activity
AA0004252molecular_functionserine-type endopeptidase activity
AA0005515molecular_functionprotein binding
AA0005576cellular_componentextracellular region
AA0006508biological_processproteolysis
AA0097180cellular_componentserine protease inhibitor complex
AA0097655molecular_functionserpin family protein binding
AB0004866molecular_functionendopeptidase inhibitor activity
AC0004175molecular_functionendopeptidase activity
AC0004252molecular_functionserine-type endopeptidase activity
AC0005515molecular_functionprotein binding
AC0005576cellular_componentextracellular region
AC0006508biological_processproteolysis
AC0097180cellular_componentserine protease inhibitor complex
AC0097655molecular_functionserpin family protein binding
AD0004866molecular_functionendopeptidase inhibitor activity
AE0004175molecular_functionendopeptidase activity
AE0004252molecular_functionserine-type endopeptidase activity
AE0005515molecular_functionprotein binding
AE0005576cellular_componentextracellular region
AE0006508biological_processproteolysis
AE0097180cellular_componentserine protease inhibitor complex
AE0097655molecular_functionserpin family protein binding
AF0004866molecular_functionendopeptidase inhibitor activity
AG0004175molecular_functionendopeptidase activity
AG0004252molecular_functionserine-type endopeptidase activity
AG0005515molecular_functionprotein binding
AG0005576cellular_componentextracellular region
AG0006508biological_processproteolysis
AG0097180cellular_componentserine protease inhibitor complex
AG0097655molecular_functionserpin family protein binding
AH0004866molecular_functionendopeptidase inhibitor activity
AI0004175molecular_functionendopeptidase activity
AI0004252molecular_functionserine-type endopeptidase activity
AI0005515molecular_functionprotein binding
AI0005576cellular_componentextracellular region
AI0006508biological_processproteolysis
AI0097180cellular_componentserine protease inhibitor complex
AI0097655molecular_functionserpin family protein binding
AJ0004866molecular_functionendopeptidase inhibitor activity
AK0004175molecular_functionendopeptidase activity
AK0004252molecular_functionserine-type endopeptidase activity
AK0005515molecular_functionprotein binding
AK0005576cellular_componentextracellular region
AK0006508biological_processproteolysis
AK0097180cellular_componentserine protease inhibitor complex
AK0097655molecular_functionserpin family protein binding
AL0004866molecular_functionendopeptidase inhibitor activity
AM0004175molecular_functionendopeptidase activity
AM0004252molecular_functionserine-type endopeptidase activity
AM0005515molecular_functionprotein binding
AM0005576cellular_componentextracellular region
AM0006508biological_processproteolysis
AM0097180cellular_componentserine protease inhibitor complex
AM0097655molecular_functionserpin family protein binding
AN0004866molecular_functionendopeptidase inhibitor activity
AO0004175molecular_functionendopeptidase activity
AO0004252molecular_functionserine-type endopeptidase activity
AO0005515molecular_functionprotein binding
AO0005576cellular_componentextracellular region
AO0006508biological_processproteolysis
AO0097180cellular_componentserine protease inhibitor complex
AO0097655molecular_functionserpin family protein binding
AP0004866molecular_functionendopeptidase inhibitor activity
AQ0004175molecular_functionendopeptidase activity
AQ0004252molecular_functionserine-type endopeptidase activity
AQ0005515molecular_functionprotein binding
AQ0005576cellular_componentextracellular region
AQ0006508biological_processproteolysis
AQ0097180cellular_componentserine protease inhibitor complex
AQ0097655molecular_functionserpin family protein binding
AR0004866molecular_functionendopeptidase inhibitor activity
AS0004175molecular_functionendopeptidase activity
AS0004252molecular_functionserine-type endopeptidase activity
AS0005515molecular_functionprotein binding
AS0005576cellular_componentextracellular region
AS0006508biological_processproteolysis
AS0097180cellular_componentserine protease inhibitor complex
AS0097655molecular_functionserpin family protein binding
AT0004866molecular_functionendopeptidase inhibitor activity
AU0004175molecular_functionendopeptidase activity
AU0004252molecular_functionserine-type endopeptidase activity
AU0005515molecular_functionprotein binding
AU0005576cellular_componentextracellular region
AU0006508biological_processproteolysis
AU0097180cellular_componentserine protease inhibitor complex
AU0097655molecular_functionserpin family protein binding
AV0004866molecular_functionendopeptidase inhibitor activity
BA0004175molecular_functionendopeptidase activity
BA0004252molecular_functionserine-type endopeptidase activity
BA0005515molecular_functionprotein binding
BA0005576cellular_componentextracellular region
BA0006508biological_processproteolysis
BA0097180cellular_componentserine protease inhibitor complex
BA0097655molecular_functionserpin family protein binding
BB0004866molecular_functionendopeptidase inhibitor activity
BC0004175molecular_functionendopeptidase activity
BC0004252molecular_functionserine-type endopeptidase activity
BC0005515molecular_functionprotein binding
BC0005576cellular_componentextracellular region
BC0006508biological_processproteolysis
BC0097180cellular_componentserine protease inhibitor complex
BC0097655molecular_functionserpin family protein binding
BD0004866molecular_functionendopeptidase inhibitor activity
BE0004175molecular_functionendopeptidase activity
BE0004252molecular_functionserine-type endopeptidase activity
BE0005515molecular_functionprotein binding
BE0005576cellular_componentextracellular region
BE0006508biological_processproteolysis
BE0097180cellular_componentserine protease inhibitor complex
BE0097655molecular_functionserpin family protein binding
BF0004866molecular_functionendopeptidase inhibitor activity
BG0004175molecular_functionendopeptidase activity
BG0004252molecular_functionserine-type endopeptidase activity
BG0005515molecular_functionprotein binding
BG0005576cellular_componentextracellular region
BG0006508biological_processproteolysis
BG0097180cellular_componentserine protease inhibitor complex
BG0097655molecular_functionserpin family protein binding
BH0004866molecular_functionendopeptidase inhibitor activity
BI0004175molecular_functionendopeptidase activity
BI0004252molecular_functionserine-type endopeptidase activity
BI0005515molecular_functionprotein binding
BI0005576cellular_componentextracellular region
BI0006508biological_processproteolysis
BI0097180cellular_componentserine protease inhibitor complex
BI0097655molecular_functionserpin family protein binding
BJ0004866molecular_functionendopeptidase inhibitor activity
BK0004175molecular_functionendopeptidase activity
BK0004252molecular_functionserine-type endopeptidase activity
BK0005515molecular_functionprotein binding
BK0005576cellular_componentextracellular region
BK0006508biological_processproteolysis
BK0097180cellular_componentserine protease inhibitor complex
BK0097655molecular_functionserpin family protein binding
BL0004866molecular_functionendopeptidase inhibitor activity
BM0004175molecular_functionendopeptidase activity
BM0004252molecular_functionserine-type endopeptidase activity
BM0005515molecular_functionprotein binding
BM0005576cellular_componentextracellular region
BM0006508biological_processproteolysis
BM0097180cellular_componentserine protease inhibitor complex
BM0097655molecular_functionserpin family protein binding
BN0004866molecular_functionendopeptidase inhibitor activity
BO0004175molecular_functionendopeptidase activity
BO0004252molecular_functionserine-type endopeptidase activity
BO0005515molecular_functionprotein binding
BO0005576cellular_componentextracellular region
BO0006508biological_processproteolysis
BO0097180cellular_componentserine protease inhibitor complex
BO0097655molecular_functionserpin family protein binding
BP0004866molecular_functionendopeptidase inhibitor activity
BQ0004175molecular_functionendopeptidase activity
BQ0004252molecular_functionserine-type endopeptidase activity
BQ0005515molecular_functionprotein binding
BQ0005576cellular_componentextracellular region
BQ0006508biological_processproteolysis
BQ0097180cellular_componentserine protease inhibitor complex
BQ0097655molecular_functionserpin family protein binding
BR0004866molecular_functionendopeptidase inhibitor activity
BS0004175molecular_functionendopeptidase activity
BS0004252molecular_functionserine-type endopeptidase activity
BS0005515molecular_functionprotein binding
BS0005576cellular_componentextracellular region
BS0006508biological_processproteolysis
BS0097180cellular_componentserine protease inhibitor complex
BS0097655molecular_functionserpin family protein binding
BT0004866molecular_functionendopeptidase inhibitor activity
BU0004175molecular_functionendopeptidase activity
BU0004252molecular_functionserine-type endopeptidase activity
BU0005515molecular_functionprotein binding
BU0005576cellular_componentextracellular region
BU0006508biological_processproteolysis
BU0097180cellular_componentserine protease inhibitor complex
BU0097655molecular_functionserpin family protein binding
BV0004866molecular_functionendopeptidase inhibitor activity
CA0004175molecular_functionendopeptidase activity
CA0004252molecular_functionserine-type endopeptidase activity
CA0005515molecular_functionprotein binding
CA0005576cellular_componentextracellular region
CA0006508biological_processproteolysis
CA0097180cellular_componentserine protease inhibitor complex
CA0097655molecular_functionserpin family protein binding
CB0004866molecular_functionendopeptidase inhibitor activity
CC0004175molecular_functionendopeptidase activity
CC0004252molecular_functionserine-type endopeptidase activity
CC0005515molecular_functionprotein binding
CC0005576cellular_componentextracellular region
CC0006508biological_processproteolysis
CC0097180cellular_componentserine protease inhibitor complex
CC0097655molecular_functionserpin family protein binding
CD0004866molecular_functionendopeptidase inhibitor activity
CE0004175molecular_functionendopeptidase activity
CE0004252molecular_functionserine-type endopeptidase activity
CE0005515molecular_functionprotein binding
CE0005576cellular_componentextracellular region
CE0006508biological_processproteolysis
CE0097180cellular_componentserine protease inhibitor complex
CE0097655molecular_functionserpin family protein binding
CF0004866molecular_functionendopeptidase inhibitor activity
CG0004175molecular_functionendopeptidase activity
CG0004252molecular_functionserine-type endopeptidase activity
CG0005515molecular_functionprotein binding
CG0005576cellular_componentextracellular region
CG0006508biological_processproteolysis
CG0097180cellular_componentserine protease inhibitor complex
CG0097655molecular_functionserpin family protein binding
CH0004866molecular_functionendopeptidase inhibitor activity
CI0004175molecular_functionendopeptidase activity
CI0004252molecular_functionserine-type endopeptidase activity
CI0005515molecular_functionprotein binding
CI0005576cellular_componentextracellular region
CI0006508biological_processproteolysis
CI0097180cellular_componentserine protease inhibitor complex
CI0097655molecular_functionserpin family protein binding
CJ0004866molecular_functionendopeptidase inhibitor activity
CK0004175molecular_functionendopeptidase activity
CK0004252molecular_functionserine-type endopeptidase activity
CK0005515molecular_functionprotein binding
CK0005576cellular_componentextracellular region
CK0006508biological_processproteolysis
CK0097180cellular_componentserine protease inhibitor complex
CK0097655molecular_functionserpin family protein binding
CL0004866molecular_functionendopeptidase inhibitor activity
CM0004175molecular_functionendopeptidase activity
CM0004252molecular_functionserine-type endopeptidase activity
CM0005515molecular_functionprotein binding
CM0005576cellular_componentextracellular region
CM0006508biological_processproteolysis
CM0097180cellular_componentserine protease inhibitor complex
CM0097655molecular_functionserpin family protein binding
CN0004866molecular_functionendopeptidase inhibitor activity
CO0004175molecular_functionendopeptidase activity
CO0004252molecular_functionserine-type endopeptidase activity
CO0005515molecular_functionprotein binding
CO0005576cellular_componentextracellular region
CO0006508biological_processproteolysis
CO0097180cellular_componentserine protease inhibitor complex
CO0097655molecular_functionserpin family protein binding
CP0004866molecular_functionendopeptidase inhibitor activity
CQ0004175molecular_functionendopeptidase activity
CQ0004252molecular_functionserine-type endopeptidase activity
CQ0005515molecular_functionprotein binding
CQ0005576cellular_componentextracellular region
CQ0006508biological_processproteolysis
CQ0097180cellular_componentserine protease inhibitor complex
CQ0097655molecular_functionserpin family protein binding
CR0004866molecular_functionendopeptidase inhibitor activity
CS0004175molecular_functionendopeptidase activity
CS0004252molecular_functionserine-type endopeptidase activity
CS0005515molecular_functionprotein binding
CS0005576cellular_componentextracellular region
CS0006508biological_processproteolysis
CS0097180cellular_componentserine protease inhibitor complex
CS0097655molecular_functionserpin family protein binding
CT0004866molecular_functionendopeptidase inhibitor activity
CU0004175molecular_functionendopeptidase activity
CU0004252molecular_functionserine-type endopeptidase activity
CU0005515molecular_functionprotein binding
CU0005576cellular_componentextracellular region
CU0006508biological_processproteolysis
CU0097180cellular_componentserine protease inhibitor complex
CU0097655molecular_functionserpin family protein binding
CV0004866molecular_functionendopeptidase inhibitor activity
DA0004175molecular_functionendopeptidase activity
DA0004252molecular_functionserine-type endopeptidase activity
DA0005515molecular_functionprotein binding
DA0005576cellular_componentextracellular region
DA0006508biological_processproteolysis
DA0097180cellular_componentserine protease inhibitor complex
DA0097655molecular_functionserpin family protein binding
DB0004866molecular_functionendopeptidase inhibitor activity
DC0004175molecular_functionendopeptidase activity
DC0004252molecular_functionserine-type endopeptidase activity
DC0005515molecular_functionprotein binding
DC0005576cellular_componentextracellular region
DC0006508biological_processproteolysis
DC0097180cellular_componentserine protease inhibitor complex
DC0097655molecular_functionserpin family protein binding
DD0004866molecular_functionendopeptidase inhibitor activity
DE0004175molecular_functionendopeptidase activity
DE0004252molecular_functionserine-type endopeptidase activity
DE0005515molecular_functionprotein binding
DE0005576cellular_componentextracellular region
DE0006508biological_processproteolysis
DE0097180cellular_componentserine protease inhibitor complex
DE0097655molecular_functionserpin family protein binding
DF0004866molecular_functionendopeptidase inhibitor activity
DG0004175molecular_functionendopeptidase activity
DG0004252molecular_functionserine-type endopeptidase activity
DG0005515molecular_functionprotein binding
DG0005576cellular_componentextracellular region
DG0006508biological_processproteolysis
DG0097180cellular_componentserine protease inhibitor complex
DG0097655molecular_functionserpin family protein binding
DH0004866molecular_functionendopeptidase inhibitor activity
DI0004175molecular_functionendopeptidase activity
DI0004252molecular_functionserine-type endopeptidase activity
DI0005515molecular_functionprotein binding
DI0005576cellular_componentextracellular region
DI0006508biological_processproteolysis
DI0097180cellular_componentserine protease inhibitor complex
DI0097655molecular_functionserpin family protein binding
DJ0004866molecular_functionendopeptidase inhibitor activity
DK0004175molecular_functionendopeptidase activity
DK0004252molecular_functionserine-type endopeptidase activity
DK0005515molecular_functionprotein binding
DK0005576cellular_componentextracellular region
DK0006508biological_processproteolysis
DK0097180cellular_componentserine protease inhibitor complex
DK0097655molecular_functionserpin family protein binding
DL0004866molecular_functionendopeptidase inhibitor activity
DM0004175molecular_functionendopeptidase activity
DM0004252molecular_functionserine-type endopeptidase activity
DM0005515molecular_functionprotein binding
DM0005576cellular_componentextracellular region
DM0006508biological_processproteolysis
DM0097180cellular_componentserine protease inhibitor complex
DM0097655molecular_functionserpin family protein binding
DN0004866molecular_functionendopeptidase inhibitor activity
DO0004175molecular_functionendopeptidase activity
DO0004252molecular_functionserine-type endopeptidase activity
DO0005515molecular_functionprotein binding
DO0005576cellular_componentextracellular region
DO0006508biological_processproteolysis
DO0097180cellular_componentserine protease inhibitor complex
DO0097655molecular_functionserpin family protein binding
DP0004866molecular_functionendopeptidase inhibitor activity
DQ0004175molecular_functionendopeptidase activity
DQ0004252molecular_functionserine-type endopeptidase activity
DQ0005515molecular_functionprotein binding
DQ0005576cellular_componentextracellular region
DQ0006508biological_processproteolysis
DQ0097180cellular_componentserine protease inhibitor complex
DQ0097655molecular_functionserpin family protein binding
DR0004866molecular_functionendopeptidase inhibitor activity
DS0004175molecular_functionendopeptidase activity
DS0004252molecular_functionserine-type endopeptidase activity
DS0005515molecular_functionprotein binding
DS0005576cellular_componentextracellular region
DS0006508biological_processproteolysis
DS0097180cellular_componentserine protease inhibitor complex
DS0097655molecular_functionserpin family protein binding
DT0004866molecular_functionendopeptidase inhibitor activity
DU0004175molecular_functionendopeptidase activity
DU0004252molecular_functionserine-type endopeptidase activity
DU0005515molecular_functionprotein binding
DU0005576cellular_componentextracellular region
DU0006508biological_processproteolysis
DU0097180cellular_componentserine protease inhibitor complex
DU0097655molecular_functionserpin family protein binding
DV0004866molecular_functionendopeptidase inhibitor activity
Functional Information from PROSITE/UniProt
site_idPS00134
Number of Residues6
DetailsTRYPSIN_HIS Serine proteases, trypsin family, histidine active site. VSAAHC
ChainResidueDetails
AAVAL51-CYS56

site_idPS00135
Number of Residues12
DetailsTRYPSIN_SER Serine proteases, trypsin family, serine active site. DScqGDSGGPVV
ChainResidueDetails
AAASP186-VAL197

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues9680
DetailsDomain: {"description":"Peptidase S1","evidences":[{"source":"PROSITE-ProRule","id":"PRU00274","evidenceCode":"ECO:0000255"}]}
ChainResidueDetails

site_idSWS_FT_FI2
Number of Residues132
DetailsActive site: {"description":"Charge relay system"}
ChainResidueDetails

site_idSWS_FT_FI3
Number of Residues308
DetailsBinding site: {}
ChainResidueDetails

256448

PDB entries from 2026-07-15

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