6DWO
Crystal structure of alpha-1-2-mannosidase from Enterococcus faecalis V583
Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0000224 | molecular_function | peptide-N4-(N-acetyl-beta-glucosaminyl)asparagine amidase activity |
A | 0003824 | molecular_function | catalytic activity |
A | 0005829 | cellular_component | cytosol |
A | 0005975 | biological_process | carbohydrate metabolic process |
A | 0006515 | biological_process | protein quality control for misfolded or incompletely synthesized proteins |
A | 0006516 | biological_process | glycoprotein catabolic process |
A | 0006517 | biological_process | protein deglycosylation |
A | 0030246 | molecular_function | carbohydrate binding |
A | 0046872 | molecular_function | metal ion binding |
B | 0000224 | molecular_function | peptide-N4-(N-acetyl-beta-glucosaminyl)asparagine amidase activity |
B | 0003824 | molecular_function | catalytic activity |
B | 0005829 | cellular_component | cytosol |
B | 0005975 | biological_process | carbohydrate metabolic process |
B | 0006515 | biological_process | protein quality control for misfolded or incompletely synthesized proteins |
B | 0006516 | biological_process | glycoprotein catabolic process |
B | 0006517 | biological_process | protein deglycosylation |
B | 0030246 | molecular_function | carbohydrate binding |
B | 0046872 | molecular_function | metal ion binding |
C | 0000224 | molecular_function | peptide-N4-(N-acetyl-beta-glucosaminyl)asparagine amidase activity |
C | 0003824 | molecular_function | catalytic activity |
C | 0005829 | cellular_component | cytosol |
C | 0005975 | biological_process | carbohydrate metabolic process |
C | 0006515 | biological_process | protein quality control for misfolded or incompletely synthesized proteins |
C | 0006516 | biological_process | glycoprotein catabolic process |
C | 0006517 | biological_process | protein deglycosylation |
C | 0030246 | molecular_function | carbohydrate binding |
C | 0046872 | molecular_function | metal ion binding |
D | 0000224 | molecular_function | peptide-N4-(N-acetyl-beta-glucosaminyl)asparagine amidase activity |
D | 0003824 | molecular_function | catalytic activity |
D | 0005829 | cellular_component | cytosol |
D | 0005975 | biological_process | carbohydrate metabolic process |
D | 0006515 | biological_process | protein quality control for misfolded or incompletely synthesized proteins |
D | 0006516 | biological_process | glycoprotein catabolic process |
D | 0006517 | biological_process | protein deglycosylation |
D | 0030246 | molecular_function | carbohydrate binding |
D | 0046872 | molecular_function | metal ion binding |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 4 |
Details | binding site for residue GOL A 801 |
Chain | Residue |
A | ALA13 |
A | GLN15 |
A | HIS50 |
A | GLU52 |
site_id | AC2 |
Number of Residues | 7 |
Details | binding site for residue CA A 802 |
Chain | Residue |
A | HOH952 |
A | HOH1052 |
A | ASN562 |
A | GLN563 |
A | ASP604 |
A | GOL807 |
A | GOL808 |
site_id | AC3 |
Number of Residues | 5 |
Details | binding site for residue K A 803 |
Chain | Residue |
A | ASN20 |
A | THR597 |
A | TYR599 |
A | HOH923 |
A | HOH1172 |
site_id | AC4 |
Number of Residues | 6 |
Details | binding site for residue ACT A 804 |
Chain | Residue |
A | ARG97 |
A | LEU113 |
A | ASP554 |
A | HOH1068 |
A | HOH1212 |
A | HOH1263 |
site_id | AC5 |
Number of Residues | 6 |
Details | binding site for residue ACT A 805 |
Chain | Residue |
A | THR12 |
A | ASN14 |
A | CYS23 |
A | LEU24 |
A | TRP47 |
A | PHE49 |
site_id | AC6 |
Number of Residues | 5 |
Details | binding site for residue ACT A 806 |
Chain | Residue |
A | ARG114 |
A | TYR115 |
A | ASN536 |
A | VAL537 |
A | HOH1225 |
site_id | AC7 |
Number of Residues | 10 |
Details | binding site for residue GOL A 807 |
Chain | Residue |
A | TRP68 |
A | MET359 |
A | GLU494 |
A | HIS545 |
A | GLU546 |
A | ASP602 |
A | ASP604 |
A | CA802 |
A | GOL808 |
A | HOH1052 |
site_id | AC8 |
Number of Residues | 10 |
Details | binding site for residue GOL A 808 |
Chain | Residue |
A | TRP312 |
A | ASP313 |
A | TRP350 |
A | MET359 |
A | GLU494 |
A | ASN562 |
A | ASP604 |
A | CA802 |
A | GOL807 |
A | HOH1088 |
site_id | AC9 |
Number of Residues | 7 |
Details | binding site for residue GOL A 809 |
Chain | Residue |
A | GLY45 |
A | SER46 |
A | ARG60 |
A | GLN64 |
A | ASP71 |
A | HOH959 |
A | HOH1227 |
site_id | AD1 |
Number of Residues | 7 |
Details | binding site for residue CA B 1001 |
Chain | Residue |
B | ASN562 |
B | GLN563 |
B | ASP604 |
B | GOL1006 |
B | GOL1007 |
B | HOH1166 |
B | HOH1429 |
site_id | AD2 |
Number of Residues | 5 |
Details | binding site for residue K B 1002 |
Chain | Residue |
B | ASN20 |
B | THR597 |
B | TYR599 |
B | HOH1202 |
B | HOH1326 |
site_id | AD3 |
Number of Residues | 4 |
Details | binding site for residue ACT B 1003 |
Chain | Residue |
B | ASN109 |
B | THR118 |
B | THR131 |
B | ASP133 |
site_id | AD4 |
Number of Residues | 6 |
Details | binding site for residue ACT B 1004 |
Chain | Residue |
A | PRO655 |
B | ARG97 |
B | ASP554 |
B | HOH1229 |
B | HOH1368 |
B | HOH1487 |
site_id | AD5 |
Number of Residues | 5 |
Details | binding site for residue ACT B 1005 |
Chain | Residue |
B | ARG114 |
B | TYR115 |
B | ASN536 |
B | VAL537 |
B | HOH1125 |
site_id | AD6 |
Number of Residues | 9 |
Details | binding site for residue GOL B 1006 |
Chain | Residue |
B | TRP68 |
B | GLU494 |
B | HIS545 |
B | GLU546 |
B | ASP602 |
B | ASP604 |
B | CA1001 |
B | GOL1007 |
B | HOH1429 |
site_id | AD7 |
Number of Residues | 10 |
Details | binding site for residue GOL B 1007 |
Chain | Residue |
B | MET359 |
B | GLU494 |
B | ASN562 |
B | GLN563 |
B | ASP604 |
B | CA1001 |
B | GOL1006 |
B | TRP312 |
B | ASP313 |
B | TRP350 |
site_id | AD8 |
Number of Residues | 7 |
Details | binding site for residue GOL B 1008 |
Chain | Residue |
B | ALA13 |
B | ASN14 |
B | GLN15 |
B | HIS50 |
B | GLU52 |
B | HOH1230 |
B | HOH1411 |
site_id | AD9 |
Number of Residues | 8 |
Details | binding site for residue GOL B 1009 |
Chain | Residue |
B | GLY45 |
B | SER46 |
B | TRP48 |
B | ARG60 |
B | GLN64 |
B | GLY70 |
B | ASP71 |
B | HIS74 |
site_id | AE1 |
Number of Residues | 6 |
Details | binding site for residue PO4 B 1010 |
Chain | Residue |
B | LYS162 |
B | ASP173 |
B | SER175 |
B | TYR177 |
B | HOH1258 |
B | HOH1282 |
site_id | AE2 |
Number of Residues | 8 |
Details | binding site for residue PO4 B 1011 |
Chain | Residue |
B | SER17 |
B | THR41 |
B | THR55 |
B | PHE90 |
B | GLN93 |
B | HOH1107 |
B | HOH1242 |
B | HOH1389 |
site_id | AE3 |
Number of Residues | 7 |
Details | binding site for residue CA C 1001 |
Chain | Residue |
C | ASN562 |
C | GLN563 |
C | ASP604 |
C | GOL1005 |
C | GOL1006 |
C | HOH1147 |
C | HOH1343 |
site_id | AE4 |
Number of Residues | 6 |
Details | binding site for residue K C 1002 |
Chain | Residue |
C | ASN20 |
C | THR597 |
C | TYR599 |
C | HOH1169 |
C | HOH1297 |
C | HOH1449 |
site_id | AE5 |
Number of Residues | 6 |
Details | binding site for residue ACT C 1003 |
Chain | Residue |
C | THR12 |
C | ASN14 |
C | CYS23 |
C | TRP47 |
C | PHE49 |
C | HOH1363 |
site_id | AE6 |
Number of Residues | 5 |
Details | binding site for residue ACT C 1004 |
Chain | Residue |
C | ARG97 |
C | LEU113 |
C | ASP554 |
C | HOH1246 |
C | HOH1272 |
site_id | AE7 |
Number of Residues | 9 |
Details | binding site for residue GOL C 1005 |
Chain | Residue |
C | TRP68 |
C | GLU494 |
C | HIS545 |
C | GLU546 |
C | ASP602 |
C | ASP604 |
C | CA1001 |
C | GOL1006 |
C | HOH1343 |
site_id | AE8 |
Number of Residues | 8 |
Details | binding site for residue GOL C 1006 |
Chain | Residue |
C | ASP313 |
C | TRP350 |
C | MET359 |
C | GLU494 |
C | ASN562 |
C | ASP604 |
C | CA1001 |
C | GOL1005 |
site_id | AE9 |
Number of Residues | 7 |
Details | binding site for residue GOL C 1007 |
Chain | Residue |
C | SER46 |
C | TRP48 |
C | ARG60 |
C | GLN64 |
C | ASP71 |
C | HIS74 |
C | HOH1382 |
site_id | AF1 |
Number of Residues | 7 |
Details | binding site for residue GOL C 1008 |
Chain | Residue |
C | ALA13 |
C | ASN14 |
C | GLN15 |
C | HIS50 |
C | GLU52 |
C | HOH1151 |
C | HOH1417 |
site_id | AF2 |
Number of Residues | 7 |
Details | binding site for residue CA D 1001 |
Chain | Residue |
D | ASN562 |
D | GLN563 |
D | ASP604 |
D | GOL1006 |
D | GOL1007 |
D | HOH1149 |
D | HOH1370 |
site_id | AF3 |
Number of Residues | 4 |
Details | binding site for residue K D 1002 |
Chain | Residue |
D | ASN20 |
D | THR597 |
D | TYR599 |
D | HOH1108 |
site_id | AF4 |
Number of Residues | 6 |
Details | binding site for residue ACT D 1003 |
Chain | Residue |
D | ASN14 |
D | CYS23 |
D | LEU24 |
D | TRP47 |
D | PHE49 |
D | HOH1386 |
site_id | AF5 |
Number of Residues | 6 |
Details | binding site for residue ACT D 1004 |
Chain | Residue |
C | PRO655 |
D | ARG97 |
D | LEU113 |
D | ASP554 |
D | HOH1189 |
D | HOH1214 |
site_id | AF6 |
Number of Residues | 4 |
Details | binding site for residue ACT D 1005 |
Chain | Residue |
D | ARG114 |
D | TYR115 |
D | ASN536 |
D | VAL537 |
site_id | AF7 |
Number of Residues | 9 |
Details | binding site for residue GOL D 1006 |
Chain | Residue |
D | TRP68 |
D | GLU494 |
D | HIS545 |
D | GLU546 |
D | ASP602 |
D | ASP604 |
D | CA1001 |
D | GOL1007 |
D | HOH1370 |
site_id | AF8 |
Number of Residues | 9 |
Details | binding site for residue GOL D 1007 |
Chain | Residue |
D | TRP312 |
D | ASP313 |
D | TRP350 |
D | MET359 |
D | GLU494 |
D | ASN562 |
D | ASP604 |
D | CA1001 |
D | GOL1006 |
site_id | AF9 |
Number of Residues | 6 |
Details | binding site for residue GOL D 1008 |
Chain | Residue |
D | ALA13 |
D | ASN14 |
D | GLN15 |
D | HIS50 |
D | GLU52 |
D | HOH1228 |
site_id | AG1 |
Number of Residues | 5 |
Details | binding site for residue GOL D 1009 |
Chain | Residue |
D | GLY45 |
D | SER46 |
D | ARG60 |
D | GLN64 |
D | ASP71 |