6DUQ
Structure of a Rho-NusG KOW domain complex
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003676 | molecular_function | nucleic acid binding |
| A | 0003723 | molecular_function | RNA binding |
| A | 0004386 | molecular_function | helicase activity |
| A | 0005515 | molecular_function | protein binding |
| A | 0005524 | molecular_function | ATP binding |
| A | 0005829 | cellular_component | cytosol |
| A | 0006353 | biological_process | DNA-templated transcription termination |
| A | 0008186 | molecular_function | ATP-dependent activity, acting on RNA |
| A | 0016020 | cellular_component | membrane |
| A | 0016787 | molecular_function | hydrolase activity |
| A | 0016887 | molecular_function | ATP hydrolysis activity |
| A | 0042802 | molecular_function | identical protein binding |
| B | 0003676 | molecular_function | nucleic acid binding |
| B | 0003723 | molecular_function | RNA binding |
| B | 0004386 | molecular_function | helicase activity |
| B | 0005515 | molecular_function | protein binding |
| B | 0005524 | molecular_function | ATP binding |
| B | 0005829 | cellular_component | cytosol |
| B | 0006353 | biological_process | DNA-templated transcription termination |
| B | 0008186 | molecular_function | ATP-dependent activity, acting on RNA |
| B | 0016020 | cellular_component | membrane |
| B | 0016787 | molecular_function | hydrolase activity |
| B | 0016887 | molecular_function | ATP hydrolysis activity |
| B | 0042802 | molecular_function | identical protein binding |
| C | 0003676 | molecular_function | nucleic acid binding |
| C | 0003723 | molecular_function | RNA binding |
| C | 0004386 | molecular_function | helicase activity |
| C | 0005515 | molecular_function | protein binding |
| C | 0005524 | molecular_function | ATP binding |
| C | 0005829 | cellular_component | cytosol |
| C | 0006353 | biological_process | DNA-templated transcription termination |
| C | 0008186 | molecular_function | ATP-dependent activity, acting on RNA |
| C | 0016020 | cellular_component | membrane |
| C | 0016787 | molecular_function | hydrolase activity |
| C | 0016887 | molecular_function | ATP hydrolysis activity |
| C | 0042802 | molecular_function | identical protein binding |
| D | 0003676 | molecular_function | nucleic acid binding |
| D | 0003723 | molecular_function | RNA binding |
| D | 0004386 | molecular_function | helicase activity |
| D | 0005515 | molecular_function | protein binding |
| D | 0005524 | molecular_function | ATP binding |
| D | 0005829 | cellular_component | cytosol |
| D | 0006353 | biological_process | DNA-templated transcription termination |
| D | 0008186 | molecular_function | ATP-dependent activity, acting on RNA |
| D | 0016020 | cellular_component | membrane |
| D | 0016787 | molecular_function | hydrolase activity |
| D | 0016887 | molecular_function | ATP hydrolysis activity |
| D | 0042802 | molecular_function | identical protein binding |
| E | 0003676 | molecular_function | nucleic acid binding |
| E | 0003723 | molecular_function | RNA binding |
| E | 0004386 | molecular_function | helicase activity |
| E | 0005515 | molecular_function | protein binding |
| E | 0005524 | molecular_function | ATP binding |
| E | 0005829 | cellular_component | cytosol |
| E | 0006353 | biological_process | DNA-templated transcription termination |
| E | 0008186 | molecular_function | ATP-dependent activity, acting on RNA |
| E | 0016020 | cellular_component | membrane |
| E | 0016787 | molecular_function | hydrolase activity |
| E | 0016887 | molecular_function | ATP hydrolysis activity |
| E | 0042802 | molecular_function | identical protein binding |
| F | 0003676 | molecular_function | nucleic acid binding |
| F | 0003723 | molecular_function | RNA binding |
| F | 0004386 | molecular_function | helicase activity |
| F | 0005515 | molecular_function | protein binding |
| F | 0005524 | molecular_function | ATP binding |
| F | 0005829 | cellular_component | cytosol |
| F | 0006353 | biological_process | DNA-templated transcription termination |
| F | 0008186 | molecular_function | ATP-dependent activity, acting on RNA |
| F | 0016020 | cellular_component | membrane |
| F | 0016787 | molecular_function | hydrolase activity |
| F | 0016887 | molecular_function | ATP hydrolysis activity |
| F | 0042802 | molecular_function | identical protein binding |
| G | 0003676 | molecular_function | nucleic acid binding |
| G | 0003723 | molecular_function | RNA binding |
| G | 0004386 | molecular_function | helicase activity |
| G | 0005515 | molecular_function | protein binding |
| G | 0005524 | molecular_function | ATP binding |
| G | 0005829 | cellular_component | cytosol |
| G | 0006353 | biological_process | DNA-templated transcription termination |
| G | 0008186 | molecular_function | ATP-dependent activity, acting on RNA |
| G | 0016020 | cellular_component | membrane |
| G | 0016787 | molecular_function | hydrolase activity |
| G | 0016887 | molecular_function | ATP hydrolysis activity |
| G | 0042802 | molecular_function | identical protein binding |
| H | 0003676 | molecular_function | nucleic acid binding |
| H | 0003723 | molecular_function | RNA binding |
| H | 0004386 | molecular_function | helicase activity |
| H | 0005515 | molecular_function | protein binding |
| H | 0005524 | molecular_function | ATP binding |
| H | 0005829 | cellular_component | cytosol |
| H | 0006353 | biological_process | DNA-templated transcription termination |
| H | 0008186 | molecular_function | ATP-dependent activity, acting on RNA |
| H | 0016020 | cellular_component | membrane |
| H | 0016787 | molecular_function | hydrolase activity |
| H | 0016887 | molecular_function | ATP hydrolysis activity |
| H | 0042802 | molecular_function | identical protein binding |
| I | 0003676 | molecular_function | nucleic acid binding |
| I | 0003723 | molecular_function | RNA binding |
| I | 0004386 | molecular_function | helicase activity |
| I | 0005515 | molecular_function | protein binding |
| I | 0005524 | molecular_function | ATP binding |
| I | 0005829 | cellular_component | cytosol |
| I | 0006353 | biological_process | DNA-templated transcription termination |
| I | 0008186 | molecular_function | ATP-dependent activity, acting on RNA |
| I | 0016020 | cellular_component | membrane |
| I | 0016787 | molecular_function | hydrolase activity |
| I | 0016887 | molecular_function | ATP hydrolysis activity |
| I | 0042802 | molecular_function | identical protein binding |
| J | 0003676 | molecular_function | nucleic acid binding |
| J | 0003723 | molecular_function | RNA binding |
| J | 0004386 | molecular_function | helicase activity |
| J | 0005515 | molecular_function | protein binding |
| J | 0005524 | molecular_function | ATP binding |
| J | 0005829 | cellular_component | cytosol |
| J | 0006353 | biological_process | DNA-templated transcription termination |
| J | 0008186 | molecular_function | ATP-dependent activity, acting on RNA |
| J | 0016020 | cellular_component | membrane |
| J | 0016787 | molecular_function | hydrolase activity |
| J | 0016887 | molecular_function | ATP hydrolysis activity |
| J | 0042802 | molecular_function | identical protein binding |
| K | 0003676 | molecular_function | nucleic acid binding |
| K | 0003723 | molecular_function | RNA binding |
| K | 0004386 | molecular_function | helicase activity |
| K | 0005515 | molecular_function | protein binding |
| K | 0005524 | molecular_function | ATP binding |
| K | 0005829 | cellular_component | cytosol |
| K | 0006353 | biological_process | DNA-templated transcription termination |
| K | 0008186 | molecular_function | ATP-dependent activity, acting on RNA |
| K | 0016020 | cellular_component | membrane |
| K | 0016787 | molecular_function | hydrolase activity |
| K | 0016887 | molecular_function | ATP hydrolysis activity |
| K | 0042802 | molecular_function | identical protein binding |
| L | 0003676 | molecular_function | nucleic acid binding |
| L | 0003723 | molecular_function | RNA binding |
| L | 0004386 | molecular_function | helicase activity |
| L | 0005515 | molecular_function | protein binding |
| L | 0005524 | molecular_function | ATP binding |
| L | 0005829 | cellular_component | cytosol |
| L | 0006353 | biological_process | DNA-templated transcription termination |
| L | 0008186 | molecular_function | ATP-dependent activity, acting on RNA |
| L | 0016020 | cellular_component | membrane |
| L | 0016787 | molecular_function | hydrolase activity |
| L | 0016887 | molecular_function | ATP hydrolysis activity |
| L | 0042802 | molecular_function | identical protein binding |
| M | 0032784 | biological_process | regulation of DNA-templated transcription elongation |
| N | 0032784 | biological_process | regulation of DNA-templated transcription elongation |
| O | 0032784 | biological_process | regulation of DNA-templated transcription elongation |
| P | 0032784 | biological_process | regulation of DNA-templated transcription elongation |
| Q | 0032784 | biological_process | regulation of DNA-templated transcription elongation |
| R | 0032784 | biological_process | regulation of DNA-templated transcription elongation |
| S | 0032784 | biological_process | regulation of DNA-templated transcription elongation |
| T | 0032784 | biological_process | regulation of DNA-templated transcription elongation |
| U | 0032784 | biological_process | regulation of DNA-templated transcription elongation |
| V | 0032784 | biological_process | regulation of DNA-templated transcription elongation |
| W | 0032784 | biological_process | regulation of DNA-templated transcription elongation |
| X | 0032784 | biological_process | regulation of DNA-templated transcription elongation |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 12 |
| Details | binding site for residue ADP L 1000 |
| Chain | Residue |
| K | ARG366 |
| L | PHE355 |
| L | MG1001 |
| L | BEF1002 |
| K | LYS367 |
| L | PRO179 |
| L | LYS181 |
| L | ALA182 |
| L | GLY183 |
| L | LYS184 |
| L | THR185 |
| L | MET186 |
| site_id | AC2 |
| Number of Residues | 3 |
| Details | binding site for residue MG L 1001 |
| Chain | Residue |
| L | THR185 |
| L | ADP1000 |
| L | BEF1002 |
| site_id | AC3 |
| Number of Residues | 8 |
| Details | binding site for residue BEF L 1002 |
| Chain | Residue |
| K | ARG366 |
| L | PRO180 |
| L | LYS181 |
| L | LYS184 |
| L | ARG212 |
| L | LEU320 |
| L | ADP1000 |
| L | MG1001 |
| site_id | AC4 |
| Number of Residues | 12 |
| Details | binding site for residue ADP A 1000 |
| Chain | Residue |
| A | PRO179 |
| A | LYS181 |
| A | ALA182 |
| A | GLY183 |
| A | LYS184 |
| A | THR185 |
| A | MET186 |
| A | PHE355 |
| A | MG1001 |
| A | BEF1002 |
| F | ARG366 |
| F | LYS367 |
| site_id | AC5 |
| Number of Residues | 3 |
| Details | binding site for residue MG A 1001 |
| Chain | Residue |
| A | THR185 |
| A | ADP1000 |
| A | BEF1002 |
| site_id | AC6 |
| Number of Residues | 8 |
| Details | binding site for residue BEF A 1002 |
| Chain | Residue |
| A | PRO180 |
| A | LYS181 |
| A | LYS184 |
| A | ARG212 |
| A | LEU320 |
| A | ADP1000 |
| A | MG1001 |
| F | ARG366 |
| site_id | AC7 |
| Number of Residues | 12 |
| Details | binding site for residue ADP G 1000 |
| Chain | Residue |
| G | PRO179 |
| G | LYS181 |
| G | ALA182 |
| G | GLY183 |
| G | LYS184 |
| G | THR185 |
| G | MET186 |
| G | PHE355 |
| G | MG1001 |
| G | BEF1002 |
| L | ARG366 |
| L | LYS367 |
| site_id | AC8 |
| Number of Residues | 3 |
| Details | binding site for residue MG G 1001 |
| Chain | Residue |
| G | THR185 |
| G | ADP1000 |
| G | BEF1002 |
| site_id | AC9 |
| Number of Residues | 8 |
| Details | binding site for residue BEF G 1002 |
| Chain | Residue |
| G | PRO180 |
| G | LYS181 |
| G | LYS184 |
| G | ARG212 |
| G | LEU320 |
| G | ADP1000 |
| G | MG1001 |
| L | ARG366 |
| site_id | AD1 |
| Number of Residues | 12 |
| Details | binding site for residue ADP B 1000 |
| Chain | Residue |
| A | ARG366 |
| A | LYS367 |
| B | PRO179 |
| B | LYS181 |
| B | ALA182 |
| B | GLY183 |
| B | LYS184 |
| B | THR185 |
| B | MET186 |
| B | PHE355 |
| B | MG1001 |
| B | BEF1002 |
| site_id | AD2 |
| Number of Residues | 3 |
| Details | binding site for residue MG B 1001 |
| Chain | Residue |
| B | THR185 |
| B | ADP1000 |
| B | BEF1002 |
| site_id | AD3 |
| Number of Residues | 8 |
| Details | binding site for residue BEF B 1002 |
| Chain | Residue |
| A | ARG366 |
| B | PRO180 |
| B | LYS181 |
| B | LYS184 |
| B | ARG212 |
| B | LEU320 |
| B | ADP1000 |
| B | MG1001 |
| site_id | AD4 |
| Number of Residues | 12 |
| Details | binding site for residue ADP H 1000 |
| Chain | Residue |
| H | THR185 |
| H | MET186 |
| H | PHE355 |
| H | MG1001 |
| H | BEF1002 |
| G | ARG366 |
| G | LYS367 |
| H | PRO179 |
| H | LYS181 |
| H | ALA182 |
| H | GLY183 |
| H | LYS184 |
| site_id | AD5 |
| Number of Residues | 3 |
| Details | binding site for residue MG H 1001 |
| Chain | Residue |
| H | THR185 |
| H | ADP1000 |
| H | BEF1002 |
| site_id | AD6 |
| Number of Residues | 8 |
| Details | binding site for residue BEF H 1002 |
| Chain | Residue |
| G | ARG366 |
| H | PRO180 |
| H | LYS181 |
| H | LYS184 |
| H | ARG212 |
| H | LEU320 |
| H | ADP1000 |
| H | MG1001 |
| site_id | AD7 |
| Number of Residues | 12 |
| Details | binding site for residue ADP C 1000 |
| Chain | Residue |
| B | ARG366 |
| B | LYS367 |
| C | PRO179 |
| C | LYS181 |
| C | ALA182 |
| C | GLY183 |
| C | LYS184 |
| C | THR185 |
| C | MET186 |
| C | PHE355 |
| C | MG1001 |
| C | BEF1002 |
| site_id | AD8 |
| Number of Residues | 3 |
| Details | binding site for residue MG C 1001 |
| Chain | Residue |
| C | THR185 |
| C | ADP1000 |
| C | BEF1002 |
| site_id | AD9 |
| Number of Residues | 8 |
| Details | binding site for residue BEF C 1002 |
| Chain | Residue |
| B | ARG366 |
| C | PRO180 |
| C | LYS181 |
| C | LYS184 |
| C | ARG212 |
| C | LEU320 |
| C | ADP1000 |
| C | MG1001 |
| site_id | AE1 |
| Number of Residues | 12 |
| Details | binding site for residue ADP I 1000 |
| Chain | Residue |
| H | ARG366 |
| H | LYS367 |
| I | PRO179 |
| I | LYS181 |
| I | ALA182 |
| I | GLY183 |
| I | LYS184 |
| I | THR185 |
| I | MET186 |
| I | PHE355 |
| I | MG1001 |
| I | BEF1002 |
| site_id | AE2 |
| Number of Residues | 3 |
| Details | binding site for residue MG I 1001 |
| Chain | Residue |
| I | THR185 |
| I | ADP1000 |
| I | BEF1002 |
| site_id | AE3 |
| Number of Residues | 8 |
| Details | binding site for residue BEF I 1002 |
| Chain | Residue |
| H | ARG366 |
| I | PRO180 |
| I | LYS181 |
| I | LYS184 |
| I | ARG212 |
| I | LEU320 |
| I | ADP1000 |
| I | MG1001 |
| site_id | AE4 |
| Number of Residues | 12 |
| Details | binding site for residue ADP D 1000 |
| Chain | Residue |
| C | ARG366 |
| C | LYS367 |
| D | PRO179 |
| D | LYS181 |
| D | ALA182 |
| D | GLY183 |
| D | LYS184 |
| D | THR185 |
| D | MET186 |
| D | PHE355 |
| D | MG1001 |
| D | BEF1002 |
| site_id | AE5 |
| Number of Residues | 3 |
| Details | binding site for residue MG D 1001 |
| Chain | Residue |
| D | THR185 |
| D | ADP1000 |
| D | BEF1002 |
| site_id | AE6 |
| Number of Residues | 8 |
| Details | binding site for residue BEF D 1002 |
| Chain | Residue |
| C | ARG366 |
| D | PRO180 |
| D | LYS181 |
| D | LYS184 |
| D | ARG212 |
| D | LEU320 |
| D | ADP1000 |
| D | MG1001 |
| site_id | AE7 |
| Number of Residues | 12 |
| Details | binding site for residue ADP K 1000 |
| Chain | Residue |
| J | ARG366 |
| J | LYS367 |
| K | PRO179 |
| K | LYS181 |
| K | ALA182 |
| K | GLY183 |
| K | LYS184 |
| K | THR185 |
| K | MET186 |
| K | PHE355 |
| K | MG1001 |
| K | BEF1002 |
| site_id | AE8 |
| Number of Residues | 3 |
| Details | binding site for residue MG K 1001 |
| Chain | Residue |
| K | THR185 |
| K | ADP1000 |
| K | BEF1002 |
| site_id | AE9 |
| Number of Residues | 8 |
| Details | binding site for residue BEF K 1002 |
| Chain | Residue |
| J | ARG366 |
| K | PRO180 |
| K | LYS181 |
| K | LYS184 |
| K | ARG212 |
| K | LEU320 |
| K | ADP1000 |
| K | MG1001 |
| site_id | AF1 |
| Number of Residues | 12 |
| Details | binding site for residue ADP F 1000 |
| Chain | Residue |
| E | ARG366 |
| E | LYS367 |
| F | PRO179 |
| F | LYS181 |
| F | ALA182 |
| F | GLY183 |
| F | LYS184 |
| F | THR185 |
| F | MET186 |
| F | PHE355 |
| F | MG1001 |
| F | BEF1002 |
| site_id | AF2 |
| Number of Residues | 3 |
| Details | binding site for residue MG F 1001 |
| Chain | Residue |
| F | THR185 |
| F | ADP1000 |
| F | BEF1002 |
| site_id | AF3 |
| Number of Residues | 8 |
| Details | binding site for residue BEF F 1002 |
| Chain | Residue |
| E | ARG366 |
| F | PRO180 |
| F | LYS181 |
| F | LYS184 |
| F | ARG212 |
| F | LEU320 |
| F | ADP1000 |
| F | MG1001 |
| site_id | AF4 |
| Number of Residues | 12 |
| Details | binding site for residue ADP J 1000 |
| Chain | Residue |
| I | ARG366 |
| I | LYS367 |
| J | PRO179 |
| J | LYS181 |
| J | ALA182 |
| J | GLY183 |
| J | LYS184 |
| J | THR185 |
| J | MET186 |
| J | PHE355 |
| J | MG1001 |
| J | BEF1002 |
| site_id | AF5 |
| Number of Residues | 3 |
| Details | binding site for residue MG J 1001 |
| Chain | Residue |
| J | THR185 |
| J | ADP1000 |
| J | BEF1002 |
| site_id | AF6 |
| Number of Residues | 8 |
| Details | binding site for residue BEF J 1002 |
| Chain | Residue |
| I | ARG366 |
| J | PRO180 |
| J | LYS181 |
| J | LYS184 |
| J | ARG212 |
| J | LEU320 |
| J | ADP1000 |
| J | MG1001 |
| site_id | AF7 |
| Number of Residues | 12 |
| Details | binding site for residue ADP E 1000 |
| Chain | Residue |
| D | ARG366 |
| D | LYS367 |
| E | PRO179 |
| E | LYS181 |
| E | ALA182 |
| E | GLY183 |
| E | LYS184 |
| E | THR185 |
| E | MET186 |
| E | PHE355 |
| E | MG1001 |
| E | BEF1002 |
| site_id | AF8 |
| Number of Residues | 3 |
| Details | binding site for residue MG E 1001 |
| Chain | Residue |
| E | THR185 |
| E | ADP1000 |
| E | BEF1002 |
| site_id | AF9 |
| Number of Residues | 8 |
| Details | binding site for residue BEF E 1002 |
| Chain | Residue |
| D | ARG366 |
| E | PRO180 |
| E | LYS181 |
| E | LYS184 |
| E | ARG212 |
| E | LEU320 |
| E | ADP1000 |
| E | MG1001 |
Functional Information from PROSITE/UniProt
| site_id | PS01014 |
| Number of Residues | 10 |
| Details | NUSG Transcription termination factor nusG signature. IFGRaTPVeL |
| Chain | Residue | Details |
| M | ILE164-LEU173 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 12 |
| Details | BINDING: BINDING => ECO:0000255 |
| Chain | Residue | Details |
| L | GLY169 | |
| F | GLY169 | |
| J | GLY169 | |
| E | GLY169 | |
| A | GLY169 | |
| G | GLY169 | |
| B | GLY169 | |
| H | GLY169 | |
| C | GLY169 | |
| I | GLY169 | |
| D | GLY169 | |
| K | GLY169 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 24 |
| Details | BINDING: |
| Chain | Residue | Details |
| L | LYS181 | |
| H | ARG212 | |
| C | LYS181 | |
| C | ARG212 | |
| I | LYS181 | |
| I | ARG212 | |
| D | LYS181 | |
| D | ARG212 | |
| K | LYS181 | |
| K | ARG212 | |
| F | LYS181 | |
| L | ARG212 | |
| F | ARG212 | |
| J | LYS181 | |
| J | ARG212 | |
| E | LYS181 | |
| E | ARG212 | |
| A | LYS181 | |
| A | ARG212 | |
| G | LYS181 | |
| G | ARG212 | |
| B | LYS181 | |
| B | ARG212 | |
| H | LYS181 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 12 |
| Details | SITE: RNA-binding 2 |
| Chain | Residue | Details |
| L | LYS326 | |
| F | LYS326 | |
| J | LYS326 | |
| E | LYS326 | |
| A | LYS326 | |
| G | LYS326 | |
| B | LYS326 | |
| H | LYS326 | |
| C | LYS326 | |
| I | LYS326 | |
| D | LYS326 | |
| K | LYS326 |
