6DUJ
Crystal structure of A51V variant of Human Cytochrome c
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005515 | molecular_function | protein binding |
| A | 0005634 | cellular_component | nucleus |
| A | 0005739 | cellular_component | mitochondrion |
| A | 0005743 | cellular_component | mitochondrial inner membrane |
| A | 0005758 | cellular_component | mitochondrial intermembrane space |
| A | 0005829 | cellular_component | cytosol |
| A | 0006122 | biological_process | mitochondrial electron transport, ubiquinol to cytochrome c |
| A | 0006123 | biological_process | mitochondrial electron transport, cytochrome c to oxygen |
| A | 0006915 | biological_process | apoptotic process |
| A | 0009055 | molecular_function | electron transfer activity |
| A | 0020037 | molecular_function | heme binding |
| A | 0022904 | biological_process | respiratory electron transport chain |
| A | 0045333 | biological_process | cellular respiration |
| A | 0046872 | molecular_function | metal ion binding |
| A | 0097190 | biological_process | apoptotic signaling pathway |
| A | 0097193 | biological_process | intrinsic apoptotic signaling pathway |
| A | 0097194 | biological_process | execution phase of apoptosis |
| C | 0005515 | molecular_function | protein binding |
| C | 0005634 | cellular_component | nucleus |
| C | 0005739 | cellular_component | mitochondrion |
| C | 0005743 | cellular_component | mitochondrial inner membrane |
| C | 0005758 | cellular_component | mitochondrial intermembrane space |
| C | 0005829 | cellular_component | cytosol |
| C | 0006122 | biological_process | mitochondrial electron transport, ubiquinol to cytochrome c |
| C | 0006123 | biological_process | mitochondrial electron transport, cytochrome c to oxygen |
| C | 0006915 | biological_process | apoptotic process |
| C | 0009055 | molecular_function | electron transfer activity |
| C | 0020037 | molecular_function | heme binding |
| C | 0022904 | biological_process | respiratory electron transport chain |
| C | 0045333 | biological_process | cellular respiration |
| C | 0046872 | molecular_function | metal ion binding |
| C | 0097190 | biological_process | apoptotic signaling pathway |
| C | 0097193 | biological_process | intrinsic apoptotic signaling pathway |
| C | 0097194 | biological_process | execution phase of apoptosis |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 22 |
| Details | binding site for residue HEC A 201 |
| Chain | Residue |
| A | LYS13 |
| A | TYR46 |
| A | TYR48 |
| A | THR49 |
| A | VAL51 |
| A | ASN52 |
| A | TRP59 |
| A | LEU68 |
| A | THR78 |
| A | LYS79 |
| A | MET80 |
| A | CYS14 |
| A | ILE81 |
| A | PHE82 |
| A | HOH309 |
| A | CYS17 |
| A | HIS18 |
| A | THR28 |
| A | GLY29 |
| A | PRO30 |
| A | THR40 |
| A | GLY41 |
| site_id | AC2 |
| Number of Residues | 28 |
| Details | binding site for Di-peptide HEC C 201 and CYS C 14 |
| Chain | Residue |
| C | PHE10 |
| C | LYS13 |
| C | SER15 |
| C | GLN16 |
| C | GLN16 |
| C | CYS17 |
| C | HIS18 |
| C | THR28 |
| C | THR28 |
| C | PRO30 |
| C | LEU35 |
| C | THR40 |
| C | GLY41 |
| C | TYR46 |
| C | TYR48 |
| C | THR49 |
| C | ASN52 |
| C | TRP59 |
| C | LEU64 |
| C | TYR67 |
| C | LEU68 |
| C | THR78 |
| C | LYS79 |
| C | MET80 |
| C | ILE81 |
| C | PHE82 |
| C | HOH309 |
| C | HOH310 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 4 |
| Details | Binding site: {"description":"covalent","evidences":[{"source":"PROSITE-ProRule","id":"PRU00433","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"23150584","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | Binding site: {"description":"axial binding residue","evidences":[{"source":"PROSITE-ProRule","id":"PRU00433","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"23150584","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 2 |
| Details | Binding site: {"description":"axial binding residue"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 2 |
| Details | Modified residue: {"description":"N-acetylglycine","evidences":[{"source":"PubMed","id":"13933734","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 4 |
| Details | Modified residue: {"description":"Phosphotyrosine","evidences":[{"source":"UniProtKB","id":"P62894","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI6 |
| Number of Residues | 2 |
| Details | Modified residue: {"description":"N6-succinyllysine","evidences":[{"source":"UniProtKB","id":"P62897","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI7 |
| Number of Residues | 2 |
| Details | Modified residue: {"description":"N6-succinyllysine; alternate","evidences":[{"source":"UniProtKB","id":"P62897","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI8 |
| Number of Residues | 2 |
| Details | Modified residue: {"description":"N6-acetyllysine","evidences":[{"source":"UniProtKB","id":"P62897","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
