6DSZ

Crystal structure of DDB1 in complex with DET1- and DDB1-associated protein 1 (DDA1)

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000781	cellular_component	chromosome, telomeric region
A	0003676	molecular_function	nucleic acid binding
A	0003677	molecular_function	DNA binding
A	0003684	molecular_function	damaged DNA binding
A	0005515	molecular_function	protein binding
A	0005615	cellular_component	extracellular space
A	0005634	cellular_component	nucleus
A	0005654	cellular_component	nucleoplasm
A	0005730	cellular_component	nucleolus
A	0005737	cellular_component	cytoplasm
A	0006281	biological_process	DNA repair
A	0006289	biological_process	nucleotide-excision repair
A	0006511	biological_process	ubiquitin-dependent protein catabolic process
A	0006915	biological_process	apoptotic process
A	0006974	biological_process	DNA damage response
A	0007056	biological_process	spindle assembly involved in female meiosis
A	0010498	biological_process	proteasomal protein catabolic process
A	0016055	biological_process	Wnt signaling pathway
A	0016567	biological_process	protein ubiquitination
A	0019076	biological_process	viral release from host cell
A	0030674	molecular_function	protein-macromolecule adaptor activity
A	0031464	cellular_component	Cul4A-RING E3 ubiquitin ligase complex
A	0031465	cellular_component	Cul4B-RING E3 ubiquitin ligase complex
A	0032991	cellular_component	protein-containing complex
A	0034644	biological_process	cellular response to UV
A	0035234	biological_process	ectopic germ cell programmed cell death
A	0035861	cellular_component	site of double-strand break
A	0042752	biological_process	regulation of circadian rhythm
A	0043066	biological_process	negative regulation of apoptotic process
A	0043161	biological_process	proteasome-mediated ubiquitin-dependent protein catabolic process
A	0044725	biological_process	epigenetic programming in the zygotic pronuclei
A	0044877	molecular_function	protein-containing complex binding
A	0045070	biological_process	positive regulation of viral genome replication
A	0045722	biological_process	positive regulation of gluconeogenesis
A	0045732	biological_process	positive regulation of protein catabolic process
A	0046726	biological_process	positive regulation by virus of viral protein levels in host cell
A	0048511	biological_process	rhythmic process
A	0051093	biological_process	negative regulation of developmental process
A	0051702	biological_process	biological process involved in interaction with symbiont
A	0051898	biological_process	negative regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction
A	0060337	biological_process	type I interferon-mediated signaling pathway
A	0070062	cellular_component	extracellular exosome
A	0070914	biological_process	UV-damage excision repair
A	0071987	molecular_function	WD40-repeat domain binding
A	0080008	cellular_component	Cul4-RING E3 ubiquitin ligase complex
A	0097510	biological_process	base-excision repair, AP site formation via deaminated base removal
A	0097602	molecular_function	cullin family protein binding
A	0160072	molecular_function	ubiquitin ligase complex scaffold activity
A	1901990	biological_process	regulation of mitotic cell cycle phase transition
A	2000242	biological_process	negative regulation of reproductive process
B	0000781	cellular_component	chromosome, telomeric region
B	0003676	molecular_function	nucleic acid binding
B	0003677	molecular_function	DNA binding
B	0003684	molecular_function	damaged DNA binding
B	0005515	molecular_function	protein binding
B	0005615	cellular_component	extracellular space
B	0005634	cellular_component	nucleus
B	0005654	cellular_component	nucleoplasm
B	0005730	cellular_component	nucleolus
B	0005737	cellular_component	cytoplasm
B	0006281	biological_process	DNA repair
B	0006289	biological_process	nucleotide-excision repair
B	0006511	biological_process	ubiquitin-dependent protein catabolic process
B	0006915	biological_process	apoptotic process
B	0006974	biological_process	DNA damage response
B	0007056	biological_process	spindle assembly involved in female meiosis
B	0010498	biological_process	proteasomal protein catabolic process
B	0016055	biological_process	Wnt signaling pathway
B	0016567	biological_process	protein ubiquitination
B	0019076	biological_process	viral release from host cell
B	0030674	molecular_function	protein-macromolecule adaptor activity
B	0031464	cellular_component	Cul4A-RING E3 ubiquitin ligase complex
B	0031465	cellular_component	Cul4B-RING E3 ubiquitin ligase complex
B	0032991	cellular_component	protein-containing complex
B	0034644	biological_process	cellular response to UV
B	0035234	biological_process	ectopic germ cell programmed cell death
B	0035861	cellular_component	site of double-strand break
B	0042752	biological_process	regulation of circadian rhythm
B	0043066	biological_process	negative regulation of apoptotic process
B	0043161	biological_process	proteasome-mediated ubiquitin-dependent protein catabolic process
B	0044725	biological_process	epigenetic programming in the zygotic pronuclei
B	0044877	molecular_function	protein-containing complex binding
B	0045070	biological_process	positive regulation of viral genome replication
B	0045722	biological_process	positive regulation of gluconeogenesis
B	0045732	biological_process	positive regulation of protein catabolic process
B	0046726	biological_process	positive regulation by virus of viral protein levels in host cell
B	0048511	biological_process	rhythmic process
B	0051093	biological_process	negative regulation of developmental process
B	0051702	biological_process	biological process involved in interaction with symbiont
B	0051898	biological_process	negative regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction
B	0060337	biological_process	type I interferon-mediated signaling pathway
B	0070062	cellular_component	extracellular exosome
B	0070914	biological_process	UV-damage excision repair
B	0071987	molecular_function	WD40-repeat domain binding
B	0080008	cellular_component	Cul4-RING E3 ubiquitin ligase complex
B	0097510	biological_process	base-excision repair, AP site formation via deaminated base removal
B	0097602	molecular_function	cullin family protein binding
B	0160072	molecular_function	ubiquitin ligase complex scaffold activity
B	1901990	biological_process	regulation of mitotic cell cycle phase transition
B	2000242	biological_process	negative regulation of reproductive process

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	343
Details	Region: {"description":"WD repeat beta-propeller A"}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	2
Details	Modified residue: {"description":"N-acetylserine","evidences":[{"source":"PubMed","id":"19413330","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	2
Details	Modified residue: {"description":"N6-acetyllysine","evidences":[{"source":"PubMed","id":"19608861","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	1
Details	Modified residue: {"description":"Phosphothreonine","evidences":[{"source":"UniProtKB","id":"Q9ESW0","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI5
Number of Residues	2
Details	Modified residue: {"description":"N-acetylalanine","evidences":[{"source":"PubMed","id":"22814378","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---