6DPL

Crystal Structure of Bacillus Halodurans Ribonuclease H1 K196A in Complex with an RNA/DNA Hybrid: Reaction in 10 mM Mg2+ and 200 mM Rb+ for 720 s at 21 C

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003676	molecular_function	nucleic acid binding
A	0004523	molecular_function	RNA-DNA hybrid ribonuclease activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	6
Details	binding site for residue MG A 201

Chain	Residue
A	ASP71
A	ASP192
A	HOH317
A	HOH326
b	C5
b	HOH101

---

site_id	AC2
Number of Residues	5
Details	binding site for residue MG A 202

Chain	Residue
B	U4
b	C5
A	ASP71
A	GLU109
A	ASP132

---

site_id	AC3
Number of Residues	7
Details	binding site for residue RB A 203

Chain	Residue
A	ASP192
A	TYR193
A	ARG195
A	ALA196
A	RB205
b	G6
b	HOH101

---

site_id	AC4
Number of Residues	4
Details	binding site for residue RB A 204

Chain	Residue
A	ASP132
A	GLU188
B	U4
b	C5

---

site_id	AC5
Number of Residues	4
Details	binding site for residue RB A 205

Chain	Residue
A	ASP192
A	ALA196
A	RB203
b	HOH101

---

site_id	AC6
Number of Residues	4
Details	binding site for residue RB A 206

Chain	Residue
A	LYS121
A	ASN124
A	HOH371
A	HOH406

---

site_id	AC7
Number of Residues	3
Details	binding site for residue CL A 207

Chain	Residue
A	TYR83
A	GOL213
A	HOH374

---

site_id	AC8
Number of Residues	2
Details	binding site for residue CL A 208

Chain	Residue
A	HOH351
A	HOH427

---

site_id	AC9
Number of Residues	3
Details	binding site for residue CL A 209

Chain	Residue
A	PRO177
A	HOH429
A	HOH430

---

site_id	AD1
Number of Residues	7
Details	binding site for residue GOL A 210

Chain	Residue
A	GLY76
A	ASN77
A	PRO78
A	HOH305
A	HOH361
C	DG2
b	HOH105

---

site_id	AD2
Number of Residues	7
Details	binding site for residue GOL A 211

Chain	Residue
A	ARG118
A	TYR119
A	GLU122
A	ARG123
A	GLU167
A	GOL213
A	HOH307

---

site_id	AD3
Number of Residues	4
Details	binding site for residue GOL A 212

Chain	Residue
A	GLU66
A	LYS127
A	HOH310
A	HOH311

---

site_id	AD4
Number of Residues	9
Details	binding site for residue GOL A 213

Chain	Residue
A	HIS115
A	ARG118
A	ASN170
A	CL207
A	GOL211
A	HOH304
A	HOH363
A	HOH374
A	HOH409

---

site_id	AD5
Number of Residues	3
Details	binding site for residue EDO A 214

Chain	Residue
A	LYS143
A	THR173
A	TYR174

---

site_id	AD6
Number of Residues	4
Details	binding site for residue EDO A 215

Chain	Residue
A	THR148
A	HOH397
C	DT4
C	DG5

---

site_id	AD7
Number of Residues	5
Details	binding site for residue GOL A 216

Chain	Residue
A	LYS89
A	ASN152
A	GLU153
A	ALA156
A	HOH384

---

site_id	AD8
Number of Residues	3
Details	binding site for residue GOL A 217

Chain	Residue
A	VAL150
A	ASN152
A	GLU154

---

site_id	AD9
Number of Residues	3
Details	binding site for residue EDO A 218

Chain	Residue
A	ILE80
A	HOH333
A	HOH375

---

site_id	AE1
Number of Residues	7
Details	binding site for residue EDO A 219

Chain	Residue
A	LYS180
A	GLN182
A	THR183
A	ASP184
A	HOH319
B	A3
B	U4

---

site_id	AE2
Number of Residues	8
Details	binding site for residue EDO A 220

Chain	Residue
A	ARG97
A	LYS143
A	LEU161
A	LEU169
A	ASN170
A	HIS172
A	HOH304
A	HOH329

---

site_id	AE3
Number of Residues	3
Details	binding site for residue RB B 101

Chain	Residue
B	HOH212
C	HOH204
B	U4

---

site_id	AE4
Number of Residues	3
Details	binding site for residue RB C 101

Chain	Residue
C	DT4
C	DG5
C	HOH207

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	4
Details	BINDING: BINDING => ECO:0000269|PubMed:15989951

Chain	Residue	Details
A	ASP192
A	ASP71
A	GLU109
A	ASP132

---