6DNF

Cryo-EM structure of the mitochondrial calcium uniporter MCU from the fungus Cyphellophora europaea

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005262	molecular_function	calcium channel activity
A	0005739	cellular_component	mitochondrion
A	0005743	cellular_component	mitochondrial inner membrane
A	0015292	molecular_function	uniporter activity
A	0036444	biological_process	calcium import into the mitochondrion
A	0042802	molecular_function	identical protein binding
A	0046872	molecular_function	metal ion binding
A	0051289	biological_process	protein homotetramerization
A	0051560	biological_process	mitochondrial calcium ion homeostasis
A	0070588	biological_process	calcium ion transmembrane transport
A	1990246	cellular_component	uniplex complex
B	0005262	molecular_function	calcium channel activity
B	0005739	cellular_component	mitochondrion
B	0005743	cellular_component	mitochondrial inner membrane
B	0015292	molecular_function	uniporter activity
B	0036444	biological_process	calcium import into the mitochondrion
B	0042802	molecular_function	identical protein binding
B	0046872	molecular_function	metal ion binding
B	0051289	biological_process	protein homotetramerization
B	0051560	biological_process	mitochondrial calcium ion homeostasis
B	0070588	biological_process	calcium ion transmembrane transport
B	1990246	cellular_component	uniplex complex
C	0005262	molecular_function	calcium channel activity
C	0005739	cellular_component	mitochondrion
C	0005743	cellular_component	mitochondrial inner membrane
C	0015292	molecular_function	uniporter activity
C	0036444	biological_process	calcium import into the mitochondrion
C	0042802	molecular_function	identical protein binding
C	0046872	molecular_function	metal ion binding
C	0051289	biological_process	protein homotetramerization
C	0051560	biological_process	mitochondrial calcium ion homeostasis
C	0070588	biological_process	calcium ion transmembrane transport
C	1990246	cellular_component	uniplex complex
D	0005262	molecular_function	calcium channel activity
D	0005739	cellular_component	mitochondrion
D	0005743	cellular_component	mitochondrial inner membrane
D	0015292	molecular_function	uniporter activity
D	0036444	biological_process	calcium import into the mitochondrion
D	0042802	molecular_function	identical protein binding
D	0046872	molecular_function	metal ion binding
D	0051289	biological_process	protein homotetramerization
D	0051560	biological_process	mitochondrial calcium ion homeostasis
D	0070588	biological_process	calcium ion transmembrane transport
D	1990246	cellular_component	uniplex complex

Functional Information from PDB Data

site_id	AC1
Number of Residues	4
Details	binding site for residue CA A 403

Chain	Residue
A	GLU228
B	GLU228
C	GLU228
D	GLU228

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site_id	AC2
Number of Residues	1
Details	binding site for residue DGG B 402

Chain	Residue
B	TYR232

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site_id	AC3
Number of Residues	1
Details	binding site for residue DGG B 403

Chain	Residue
B	LEU233

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site_id	AC4
Number of Residues	1
Details	binding site for residue DGG D 501

Chain	Residue
D	TYR232

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site_id	AC5
Number of Residues	1
Details	binding site for residue DGG D 502

Chain	Residue
D	LEU233

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