6DN5
SPRY domain-containing SOCS box protein 2 complexed with WDINNN(BAL) cyclic peptide inhibitor
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 7 |
| Details | binding site for residue SO4 A 301 |
| Chain | Residue |
| A | GLN151 |
| A | GLY155 |
| A | THR156 |
| A | GLN157 |
| A | LYS195 |
| A | HOH404 |
| A | HOH408 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | binding site for residue SO4 A 302 |
| Chain | Residue |
| A | ARG69 |
| A | ARG82 |
| A | ARG45 |
| A | HIS46 |
| site_id | AC3 |
| Number of Residues | 5 |
| Details | binding site for Ligand residues BAL B 8 through TRP B 1 bound to ASN B 6 |
| Chain | Residue |
| A | GLY184 |
| A | ARG215 |
| B | ASP2 |
| B | ASN6 |
| B | HOH104 |
Functional Information from PROSITE/UniProt
| site_id | PS00678 |
| Number of Residues | 15 |
| Details | WD_REPEATS_1 Trp-Asp (WD) repeats signature. AALLgsNsESWGWDI |
| Chain | Residue | Details |
| A | ALA121-ILE135 |
