6DMH

A multiconformer ligand model of acylenzyme intermediate of meropenem bound to an SFC-1 E166A mutant

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0008800	molecular_function	beta-lactamase activity
A	0017001	biological_process	antibiotic catabolic process
A	0030655	biological_process	beta-lactam antibiotic catabolic process
A	0046677	biological_process	response to antibiotic

Functional Information from PDB Data

site_id	AC1
Number of Residues	6
Details	binding site for residue EDO A 301

Chain	Residue
A	PHE57
A	SER289
A	HOH445
A	HOH475
A	HOH484
A	HOH584

---

site_id	AC2
Number of Residues	6
Details	binding site for residue EDO A 302

Chain	Residue
A	GLU188
A	HOH507
A	HOH508
A	GLY156
A	ASN158
A	ALA185

---

site_id	AC3
Number of Residues	5
Details	binding site for residue EDO A 303

Chain	Residue
A	ARG94
A	GLN112
A	THR115
A	GLY116
A	GLU121

---

site_id	AC4
Number of Residues	7
Details	binding site for residue EDO A 304

Chain	Residue
A	ARG61
A	ALA62
A	ASN63
A	GLU64
A	HAR100
A	HOH454
A	HOH617

---

site_id	AC5
Number of Residues	15
Details	binding site for residue MER A 305

Chain	Residue
A	CYS69
A	SER70
A	SER130
A	ASN132
A	ASN170
A	THR216
A	LYS234
A	THR235
A	GLY236
A	THR237
A	HOH420
A	HOH547
A	HOH548
A	HOH579
A	HOH665

---