6DJK
Structure of DNA polymerase III subunit beta from Rickettsia typhi in complex with a natural product
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003677 | molecular_function | DNA binding |
| A | 0003887 | molecular_function | DNA-directed DNA polymerase activity |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0006260 | biological_process | DNA replication |
| A | 0006271 | biological_process | DNA strand elongation involved in DNA replication |
| A | 0008408 | molecular_function | 3'-5' exonuclease activity |
| A | 0009360 | cellular_component | DNA polymerase III complex |
| A | 0016740 | molecular_function | transferase activity |
| A | 0016779 | molecular_function | nucleotidyltransferase activity |
| A | 0071897 | biological_process | DNA biosynthetic process |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 7 |
| Details | binding site for residue EDO A 500 |
| Chain | Residue |
| A | ASN49 |
| A | MET50 |
| A | ASP51 |
| A | LEU52 |
| A | LEU237 |
| A | HOH602 |
| A | HOH692 |
| site_id | AC2 |
| Number of Residues | 3 |
| Details | binding site for residue EDO A 501 |
| Chain | Residue |
| B | MVA1008 |
| A | ILE252 |
| A | HOH603 |
| site_id | AC3 |
| Number of Residues | 4 |
| Details | binding site for residue PEG A 502 |
| Chain | Residue |
| A | ARG80 |
| A | LYS81 |
| A | HOH611 |
| A | HOH657 |
| site_id | AC4 |
| Number of Residues | 6 |
| Details | binding site for residues ACE B 1001 and MVA B 1002 |
| Chain | Residue |
| A | HIS175 |
| A | VAL379 |
| A | LYS380 |
| A | HOH622 |
| B | MP81003 |
| B | HOH1103 |
| site_id | AC5 |
| Number of Residues | 7 |
| Details | binding site for residues MVA B 1002 and MP8 B 1003 |
| Chain | Residue |
| A | HIS175 |
| A | MET377 |
| A | PRO378 |
| B | ACE1001 |
| B | NZC1004 |
| B | HOH1103 |
| B | HOH1104 |
| site_id | AC6 |
| Number of Residues | 9 |
| Details | binding site for residues MP8 B 1003 and NZC B 1004 |
| Chain | Residue |
| A | GLY174 |
| A | MET377 |
| A | PRO378 |
| B | ACE1001 |
| B | MVA1002 |
| B | LEU1005 |
| B | GLY1011 |
| B | HOH1104 |
| B | HOH1105 |
