6DG3
LarE, a sulfur transferase involved in synthesis of the cofactor for lactate racemase, in complex with caesium
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005524 | molecular_function | ATP binding |
| A | 0016783 | molecular_function | sulfurtransferase activity |
| A | 0016829 | molecular_function | lyase activity |
| B | 0005524 | molecular_function | ATP binding |
| B | 0016783 | molecular_function | sulfurtransferase activity |
| B | 0016829 | molecular_function | lyase activity |
| C | 0005524 | molecular_function | ATP binding |
| C | 0016783 | molecular_function | sulfurtransferase activity |
| C | 0016829 | molecular_function | lyase activity |
| D | 0005524 | molecular_function | ATP binding |
| D | 0016783 | molecular_function | sulfurtransferase activity |
| D | 0016829 | molecular_function | lyase activity |
| E | 0005524 | molecular_function | ATP binding |
| E | 0016783 | molecular_function | sulfurtransferase activity |
| E | 0016829 | molecular_function | lyase activity |
| F | 0005524 | molecular_function | ATP binding |
| F | 0016783 | molecular_function | sulfurtransferase activity |
| F | 0016829 | molecular_function | lyase activity |
| G | 0005524 | molecular_function | ATP binding |
| G | 0016783 | molecular_function | sulfurtransferase activity |
| G | 0016829 | molecular_function | lyase activity |
| H | 0005524 | molecular_function | ATP binding |
| H | 0016783 | molecular_function | sulfurtransferase activity |
| H | 0016829 | molecular_function | lyase activity |
| I | 0005524 | molecular_function | ATP binding |
| I | 0016783 | molecular_function | sulfurtransferase activity |
| I | 0016829 | molecular_function | lyase activity |
| J | 0005524 | molecular_function | ATP binding |
| J | 0016783 | molecular_function | sulfurtransferase activity |
| J | 0016829 | molecular_function | lyase activity |
| K | 0005524 | molecular_function | ATP binding |
| K | 0016783 | molecular_function | sulfurtransferase activity |
| K | 0016829 | molecular_function | lyase activity |
| L | 0005524 | molecular_function | ATP binding |
| L | 0016783 | molecular_function | sulfurtransferase activity |
| L | 0016829 | molecular_function | lyase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 3 |
| Details | binding site for residue CS A 301 |
| Chain | Residue |
| A | SER54 |
| A | PHE57 |
| A | ASP59 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | binding site for residue PO4 A 302 |
| Chain | Residue |
| A | CYS176 |
| A | SER180 |
| A | ARG212 |
| A | ARG214 |
| site_id | AC3 |
| Number of Residues | 3 |
| Details | binding site for residue CS B 301 |
| Chain | Residue |
| B | ASP59 |
| B | SER54 |
| B | PHE57 |
| site_id | AC4 |
| Number of Residues | 4 |
| Details | binding site for residue PO4 B 302 |
| Chain | Residue |
| B | CYS176 |
| B | SER180 |
| B | ARG212 |
| B | ARG214 |
| site_id | AC5 |
| Number of Residues | 3 |
| Details | binding site for residue CS C 301 |
| Chain | Residue |
| C | SER54 |
| C | PHE57 |
| C | ASP59 |
| site_id | AC6 |
| Number of Residues | 4 |
| Details | binding site for residue PO4 C 302 |
| Chain | Residue |
| C | CYS176 |
| C | SER180 |
| C | ARG212 |
| C | ARG214 |
| site_id | AC7 |
| Number of Residues | 4 |
| Details | binding site for residue CS D 301 |
| Chain | Residue |
| D | ASN53 |
| D | SER54 |
| D | PHE57 |
| D | ASP59 |
| site_id | AC8 |
| Number of Residues | 4 |
| Details | binding site for residue PO4 D 302 |
| Chain | Residue |
| D | CYS176 |
| D | SER180 |
| D | ARG212 |
| D | ARG214 |
| site_id | AC9 |
| Number of Residues | 3 |
| Details | binding site for residue CS E 301 |
| Chain | Residue |
| E | SER54 |
| E | PHE57 |
| E | ASP59 |
| site_id | AD1 |
| Number of Residues | 4 |
| Details | binding site for residue PO4 E 302 |
| Chain | Residue |
| E | CYS176 |
| E | SER180 |
| E | ARG212 |
| E | ARG214 |
| site_id | AD2 |
| Number of Residues | 2 |
| Details | binding site for residue CS F 301 |
| Chain | Residue |
| F | GLU141 |
| F | ALA144 |
| site_id | AD3 |
| Number of Residues | 3 |
| Details | binding site for residue PO4 F 302 |
| Chain | Residue |
| F | SER180 |
| F | ARG212 |
| F | ARG214 |
| site_id | AD4 |
| Number of Residues | 3 |
| Details | binding site for residue CS G 301 |
| Chain | Residue |
| G | SER54 |
| G | PHE57 |
| G | ASP59 |
| site_id | AD5 |
| Number of Residues | 3 |
| Details | binding site for residue PO4 G 302 |
| Chain | Residue |
| G | SER180 |
| G | ARG212 |
| G | ARG214 |
| site_id | AD6 |
| Number of Residues | 4 |
| Details | binding site for residue CS H 301 |
| Chain | Residue |
| H | ASN53 |
| H | SER54 |
| H | PHE57 |
| H | ASP59 |
| site_id | AD7 |
| Number of Residues | 4 |
| Details | binding site for residue PO4 H 302 |
| Chain | Residue |
| H | CYS176 |
| H | SER180 |
| H | ARG212 |
| H | ARG214 |
| site_id | AD8 |
| Number of Residues | 3 |
| Details | binding site for residue CS I 301 |
| Chain | Residue |
| I | SER54 |
| I | PHE57 |
| I | ASP59 |
| site_id | AD9 |
| Number of Residues | 4 |
| Details | binding site for residue PO4 I 302 |
| Chain | Residue |
| I | CYS176 |
| I | SER180 |
| I | ARG212 |
| I | ARG214 |
| site_id | AE1 |
| Number of Residues | 2 |
| Details | binding site for residue CS J 301 |
| Chain | Residue |
| J | GLU141 |
| J | ALA144 |
| site_id | AE2 |
| Number of Residues | 4 |
| Details | binding site for residue PO4 J 302 |
| Chain | Residue |
| J | SER180 |
| J | ARG212 |
| J | ARG214 |
| J | SER260 |
| site_id | AE3 |
| Number of Residues | 4 |
| Details | binding site for residue CS K 301 |
| Chain | Residue |
| K | ASN53 |
| K | SER54 |
| K | PHE57 |
| K | ASP59 |
| site_id | AE4 |
| Number of Residues | 4 |
| Details | binding site for residue PO4 K 302 |
| Chain | Residue |
| K | CYS176 |
| K | SER180 |
| K | ARG212 |
| K | ARG214 |
| site_id | AE5 |
| Number of Residues | 3 |
| Details | binding site for residue CS L 301 |
| Chain | Residue |
| L | SER54 |
| L | PHE57 |
| L | ASP59 |
| site_id | AE6 |
| Number of Residues | 4 |
| Details | binding site for residue PO4 L 302 |
| Chain | Residue |
| L | CYS176 |
| L | SER180 |
| L | ARG212 |
| L | ARG214 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 12 |
| Details | ACT_SITE: Nucleophile and sulfur donor => ECO:0000269|PubMed:27114550 |
| Chain | Residue | Details |
| A | CYS176 | |
| J | CYS176 | |
| K | CYS176 | |
| L | CYS176 | |
| B | CYS176 | |
| C | CYS176 | |
| D | CYS176 | |
| E | CYS176 | |
| F | CYS176 | |
| G | CYS176 | |
| H | CYS176 | |
| I | CYS176 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 12 |
| Details | MOD_RES: 2,3-didehydroalanine (Cys) => ECO:0000269|PubMed:27114550 |
| Chain | Residue | Details |
| A | CYS176 | |
| J | CYS176 | |
| K | CYS176 | |
| L | CYS176 | |
| B | CYS176 | |
| C | CYS176 | |
| D | CYS176 | |
| E | CYS176 | |
| F | CYS176 | |
| G | CYS176 | |
| H | CYS176 | |
| I | CYS176 |
