6DF8

Kaiso (ZBTB33) zinc finger DNA binding domain in complex with the specific Kaiso binding sequence (KBS), pH 6.5

Functional Information from PDB Data

site_id	AC1
Number of Residues	4
Details	binding site for residue ZN A 701

Chain	Residue
A	CYS496
A	CYS499
A	HIS512
A	HIS516

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site_id	AC2
Number of Residues	4
Details	binding site for residue ZN A 702

Chain	Residue
A	CYS524
A	CYS527
A	HIS540
A	HIS544

---

site_id	AC3
Number of Residues	4
Details	binding site for residue ZN A 703

Chain	Residue
A	CYS555
A	HIS568
A	HIS573
A	CYS552

---

site_id	AC4
Number of Residues	4
Details	binding site for residue CL A 704

Chain	Residue
A	GLU547
A	ARG548
A	ARG548
A	ARG590

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Functional Information from PROSITE/UniProt

site_id	PS00028
Number of Residues	21
Details	ZINC_FINGER_C2H2_1 Zinc finger C2H2 type domain signature. Civ..CkrsYvcltslrrHfni..H

Chain	Residue	Details
A	CYS496-HIS516
A	CYS524-HIS544
A	CYS552-HIS573

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	22
Details	ZN_FING: C2H2-type 1 => ECO:0000255|PROSITE-ProRule:PRU00042

Chain	Residue	Details
A	TYR494-HIS516

---

site_id	SWS_FT_FI2
Number of Residues	22
Details	ZN_FING: C2H2-type 2 => ECO:0000255|PROSITE-ProRule:PRU00042

Chain	Residue	Details
A	TYR522-HIS544

---

site_id	SWS_FT_FI3
Number of Residues	23
Details	ZN_FING: C2H2-type 3 => ECO:0000255|PROSITE-ProRule:PRU00042

Chain	Residue	Details
A	TYR550-HIS573

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site_id	SWS_FT_FI4
Number of Residues	3
Details	CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2) => ECO:0007744|PubMed:28112733

Chain	Residue	Details
A	LYS474
A	LYS539
A	LYS570

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site_id	SWS_FT_FI5
Number of Residues	3
Details	CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2) => ECO:0007744|PubMed:25218447, ECO:0007744|PubMed:28112733

Chain	Residue	Details
A	LYS479
A	LYS582

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