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6DF3

Crystal structure of ternary complex of IL-24 with soluble receptors IL-22RA and IL-20RB

Functional Information from GO Data
ChainGOidnamespacecontents
C0005125molecular_functioncytokine activity
C0005515molecular_functionprotein binding
C0005576cellular_componentextracellular region
C0005615cellular_componentextracellular space
C0006915biological_processapoptotic process
C0006955biological_processimmune response
C0007165biological_processsignal transduction
C0008284biological_processpositive regulation of cell population proliferation
C0008285biological_processnegative regulation of cell population proliferation
C0030336biological_processnegative regulation of cell migration
C0071222biological_processcellular response to lipopolysaccharide
C0071353biological_processcellular response to interleukin-4
Functional Information from PROSITE/UniProt
site_idPS00520
Number of Residues21
DetailsINTERLEUKIN_10 Interleukin-10 family signature. SdaesCYlvhtLLeFYLkTVF
ChainResidueDetails
CSER101-PHE121

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues2
DetailsCARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000255
ChainResidueDetails
HASN40
HGLN134
CGLN126

site_idSWS_FT_FI2
Number of Residues2
DetailsCROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin) => ECO:0000269|PubMed:23078624
ChainResidueDetails
CLYS122

237735

PDB entries from 2025-06-18

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