6DDU

mouse beta-mannosidase bound to beta-D-mannose (MANBA)

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004553	molecular_function	hydrolase activity, hydrolyzing O-glycosyl compounds
A	0004567	molecular_function	beta-mannosidase activity
A	0005537	molecular_function	mannose binding
A	0005615	cellular_component	extracellular space
A	0005764	cellular_component	lysosome
A	0005975	biological_process	carbohydrate metabolic process
A	0006516	biological_process	glycoprotein catabolic process
A	0008152	biological_process	metabolic process
A	0009313	biological_process	oligosaccharide catabolic process
A	0016787	molecular_function	hydrolase activity
A	0016798	molecular_function	hydrolase activity, acting on glycosyl bonds
A	0043202	cellular_component	lysosomal lumen

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1
Details	ACT_SITE: Proton donor => ECO:0000305|PubMed:30552791

Chain	Residue	Details
A	GLU457

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site_id	SWS_FT_FI2
Number of Residues	1
Details	ACT_SITE: Nucleophile => ECO:0000305|PubMed:30552791

Chain	Residue	Details
A	GLU554

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site_id	SWS_FT_FI3
Number of Residues	2
Details	BINDING: BINDING => ECO:0000269|PubMed:30552791, ECO:0007744|PDB:6DDU

Chain	Residue	Details
A	TRP190
A	ASN456

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site_id	SWS_FT_FI4
Number of Residues	9
Details	CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:30552791, ECO:0007744|PDB:6DDT

Chain	Residue	Details
A	ASN35
A	ASN77
A	ASN89
A	ASN113
A	ASN226
A	ASN297
A	ASN302
A	ASN736
A	ASN803

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site_id	SWS_FT_FI5
Number of Residues	1
Details	CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000255

Chain	Residue	Details
A	ASN807

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