6DC4

RSV-neutralizing human antibody AM22

Functional Information from GO Data

Chain	GOid	namespace	contents
L	0002250	biological_process	adaptive immune response
L	0002376	biological_process	immune system process
L	0005576	cellular_component	extracellular region
L	0005886	cellular_component	plasma membrane
L	0019814	cellular_component	immunoglobulin complex
L	0046872	molecular_function	metal ion binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	6
Details	binding site for residue EDO H 301

Chain	Residue
H	GLU148
H	PRO149
H	VAL150
H	ALA168
H	LEU178
H	HOH583

---

site_id	AC2
Number of Residues	5
Details	binding site for residue EDO H 302

Chain	Residue
H	ASP208
H	HOH435
H	VAL198
H	LYS206
H	VAL207

---

site_id	AC3
Number of Residues	7
Details	binding site for residue EDO H 303

Chain	Residue
H	LYS31
H	GLY96
H	THR98
H	GLY100
H	ASP100
H	HOH401
H	HOH402

---

site_id	AC4
Number of Residues	6
Details	binding site for residue EDO H 304

Chain	Residue
H	SER120
H	VAL121
H	VAL207
H	HOH412
L	GLU123
L	SER156

---

site_id	AC5
Number of Residues	4
Details	binding site for residue EDO H 305

Chain	Residue
H	ASN155
H	ALA158
H	GLN192
H	HOH527

---

site_id	AC6
Number of Residues	7
Details	binding site for residue EDO H 306

Chain	Residue
H	VAL2
H	GLN3
H	LEU4
H	TYR102
H	TRP103
H	HOH434
H	HOH553

---

site_id	AC7
Number of Residues	4
Details	binding site for residue EDO H 307

Chain	Residue
H	ARG66
H	THR68
H	GLU81
H	HOH405

---

site_id	AC8
Number of Residues	8
Details	binding site for residue EDO H 308

Chain	Residue
H	LEU141
H	VAL169
H	SER177
H	SER179
H	HOH472
H	HOH483
L	THR178
L	HOH475

---

site_id	AC9
Number of Residues	3
Details	binding site for residue EDO H 309

Chain	Residue
H	GLY100
H	LEU100
L	SER53

---

site_id	AD1
Number of Residues	5
Details	binding site for residue EDO H 310

Chain	Residue
H	LEU100
H	GLY100
H	ILE100
H	HOH521
L	EDO305

---

site_id	AD2
Number of Residues	5
Details	binding site for residue EDO L 301

Chain	Residue
L	GLN37
L	ARG45
L	GLU81
L	ASP82
L	HOH501

---

site_id	AD3
Number of Residues	7
Details	binding site for residue EDO L 302

Chain	Residue
H	VAL97
H	HOH488
L	HIS32
L	ALA34
L	SER91
L	PHE96
L	HOH474

---

site_id	AD4
Number of Residues	4
Details	binding site for residue EDO L 303

Chain	Residue
H	GLY42
L	TYR87
L	PRO100
L	HOH508

---

site_id	AD5
Number of Residues	6
Details	binding site for residue EDO L 304

Chain	Residue
H	GLN39
L	GLN38
L	LYS39
L	PRO40
L	VAL85
L	TYR87

---

site_id	AD6
Number of Residues	5
Details	binding site for residue EDO L 305

Chain	Residue
H	ILE100
H	EDO310
L	ALA55
L	THR56
L	HOH523

---

site_id	AD7
Number of Residues	8
Details	binding site for residue EDO L 306

Chain	Residue
L	PRO119
L	TYR186
L	PHE209
L	ASN210
L	ARG211
L	GLY212
L	GLU213
L	HOH446

---

site_id	AD8
Number of Residues	5
Details	binding site for residue EDO L 307

Chain	Residue
L	GLN166
L	ASP167
L	SER168
L	SER171
L	HOH410

---

Functional Information from PROSITE/UniProt

site_id	PS00290
Number of Residues	7
Details	IG_MHC Immunoglobulins and major histocompatibility complex proteins signature. YACEVTH

Chain	Residue	Details
L	TYR192-HIS198
H	TYR194-HIS200

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