6D9M

T4-Lysozyme fusion to Geobacter GGDEF

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003796	molecular_function	lysozyme activity
A	0003824	molecular_function	catalytic activity
A	0009253	biological_process	peptidoglycan catabolic process
A	0016787	molecular_function	hydrolase activity
A	0016798	molecular_function	hydrolase activity, acting on glycosyl bonds
A	0016998	biological_process	cell wall macromolecule catabolic process
A	0030430	cellular_component	host cell cytoplasm
A	0031640	biological_process	killing of cells of another organism
A	0042742	biological_process	defense response to bacterium
A	0044659	biological_process	viral release from host cell by cytolysis

Functional Information from PDB Data

site_id	AC1
Number of Residues	11
Details	binding site for residue GTP A 201

Chain	Residue
A	LYS-147
A	HOH511
A	HOH559
A	VAL69
A	ARG70
A	ASP73
A	VAL88
A	THR90
A	VAL98
A	ARG101
A	HOH495

---

site_id	AC2
Number of Residues	16
Details	binding site for residue GTP A 202

Chain	Residue
A	THR-142
A	ASN-19
A	ARG-15
A	ILE16
A	ASP19
A	ARG20
A	LYS23
A	ARG24
A	ARG27
A	ACT207
A	HOH304
A	HOH317
A	HOH325
A	HOH376
A	HOH450
A	HOH537

---

site_id	AC3
Number of Residues	12
Details	binding site for residue GMP A 203

Chain	Residue
A	PHE42
A	LYS43
A	ASN46
A	HIS51
A	GLY54
A	SER55
A	LEU58
A	GLY80
A	ASP81
A	POP204
A	HOH348
A	HOH548

---

site_id	AC4
Number of Residues	16
Details	binding site for residue POP A 204

Chain	Residue
A	ASP38
A	LEU39
A	ASP40
A	PHE41
A	PHE42
A	LYS43
A	ASP81
A	LYS152
A	LYS156
A	GMP203
A	MG205
A	HOH318
A	HOH365
A	HOH408
A	HOH444
A	HOH464

---

site_id	AC5
Number of Residues	5
Details	binding site for residue MG A 205

Chain	Residue
A	ASP38
A	LEU39
A	ASP81
A	POP204
A	HOH365

---

site_id	AC6
Number of Residues	5
Details	binding site for residue GOL A 206

Chain	Residue
A	ALA96
A	GLU100
A	TYR127
A	VAL159
A	HOH580

---

site_id	AC7
Number of Residues	6
Details	binding site for residue ACT A 207

Chain	Residue
A	ASN-19
A	THR-21
A	PRO-20
A	ARG-18
A	GTP202
A	HOH455

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1
Details	Active site: {"description":"Proton donor/acceptor","evidences":[{"source":"HAMAP-Rule","id":"MF_04110","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"3382407","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"7831309","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"8266098","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	1
Details	Active site: {"description":"Proton donor/acceptor","evidences":[{"source":"HAMAP-Rule","id":"MF_04110","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"1892846","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"3382407","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"7831309","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"8266098","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	2
Details	Binding site: {"evidences":[{"source":"PubMed","id":"8266098","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	2
Details	Binding site: {"evidences":[{"source":"PubMed","id":"7831309","evidenceCode":"ECO:0000303"}]}

Chain

Residue

Details

---

Catalytic Information from CSA

site_id	MCSA1
Number of Residues	2
Details	M-CSA 921

Chain	Residue	Details
A	GLN-152	proton shuttle (general acid/base)
A	ASP-143	covalent catalysis

---