6CZZ
Crystal structure of Arabidopsis thaliana phosphoserine aminotransferase isoform 1 (AtPSAT1) in complex with PLP-phosphoserine geminal diamine intermediate
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004648 | molecular_function | O-phospho-L-serine:2-oxoglutarate aminotransferase activity |
| A | 0006564 | biological_process | L-serine biosynthetic process |
| B | 0004648 | molecular_function | O-phospho-L-serine:2-oxoglutarate aminotransferase activity |
| B | 0006564 | biological_process | L-serine biosynthetic process |
| C | 0004648 | molecular_function | O-phospho-L-serine:2-oxoglutarate aminotransferase activity |
| C | 0006564 | biological_process | L-serine biosynthetic process |
| D | 0004648 | molecular_function | O-phospho-L-serine:2-oxoglutarate aminotransferase activity |
| D | 0006564 | biological_process | L-serine biosynthetic process |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 6 |
| Details | binding site for residue NA A 503 |
| Chain | Residue |
| A | ALA93 |
| A | ALA93 |
| A | HOH714 |
| A | HOH714 |
| A | HOH923 |
| A | HOH923 |
| site_id | AC2 |
| Number of Residues | 6 |
| Details | binding site for residue NA C 503 |
| Chain | Residue |
| C | HOH635 |
| C | HOH885 |
| C | HOH885 |
| C | ALA93 |
| C | ALA93 |
| C | HOH635 |
| site_id | AC3 |
| Number of Residues | 25 |
| Details | binding site for residues PLP A 501 and SEP A 502 |
| Chain | Residue |
| A | ALA78 |
| A | GLY144 |
| A | ALA145 |
| A | THR146 |
| A | TRP171 |
| A | CYS217 |
| A | ASN219 |
| A | THR221 |
| A | ILE222 |
| A | ASP241 |
| A | SER243 |
| A | GLN264 |
| A | LYS265 |
| A | HIS396 |
| A | ARG397 |
| A | ARG403 |
| A | HOH633 |
| A | HOH671 |
| A | HOH676 |
| A | HOH771 |
| B | HIS110 |
| B | ARG111 |
| B | ASN306 |
| B | THR307 |
| B | HOH638 |
| site_id | AC4 |
| Number of Residues | 23 |
| Details | binding site for Di-peptide PLP B 501 and LYS B 265 |
| Chain | Residue |
| A | ASN306 |
| A | THR307 |
| A | HOH642 |
| A | HOH662 |
| B | ALA78 |
| B | ALA81 |
| B | GLY144 |
| B | ALA145 |
| B | THR146 |
| B | TRP171 |
| B | CYS217 |
| B | THR221 |
| B | ASP241 |
| B | SER243 |
| B | SER244 |
| B | ALA263 |
| B | GLN264 |
| B | ASN266 |
| B | TYR407 |
| B | SEP502 |
| B | HOH612 |
| B | HOH656 |
| B | HOH834 |
| site_id | AC5 |
| Number of Residues | 24 |
| Details | binding site for residues PLP B 501 and SEP B 502 |
| Chain | Residue |
| A | HIS110 |
| A | ARG111 |
| A | ASN306 |
| A | THR307 |
| A | HOH662 |
| B | ALA78 |
| B | GLY144 |
| B | ALA145 |
| B | THR146 |
| B | TRP171 |
| B | CYS217 |
| B | THR221 |
| B | ILE222 |
| B | ASP241 |
| B | SER243 |
| B | GLN264 |
| B | LYS265 |
| B | HIS396 |
| B | ARG397 |
| B | ARG403 |
| B | HOH610 |
| B | HOH612 |
| B | HOH683 |
| B | HOH834 |
| site_id | AC6 |
| Number of Residues | 25 |
| Details | binding site for residues PLP C 501 and SEP C 502 |
| Chain | Residue |
| C | ARG403 |
| C | HOH607 |
| C | HOH621 |
| C | HOH727 |
| C | HOH830 |
| D | HIS110 |
| D | ARG111 |
| D | ASN306 |
| D | THR307 |
| D | HOH657 |
| C | ALA78 |
| C | GLY144 |
| C | ALA145 |
| C | THR146 |
| C | TRP171 |
| C | CYS217 |
| C | ASN219 |
| C | THR221 |
| C | ILE222 |
| C | ASP241 |
| C | SER243 |
| C | GLN264 |
| C | LYS265 |
| C | HIS396 |
| C | ARG397 |
| site_id | AC7 |
| Number of Residues | 24 |
| Details | binding site for Di-peptide PLP C 501 and LYS C 265 |
| Chain | Residue |
| C | ALA78 |
| C | ALA81 |
| C | GLY144 |
| C | ALA145 |
| C | THR146 |
| C | TRP171 |
| C | CYS217 |
| C | ASN219 |
| C | THR221 |
| C | ASP241 |
| C | SER243 |
| C | SER244 |
| C | ALA263 |
| C | GLN264 |
| C | ASN266 |
| C | TYR407 |
| C | SEP502 |
| C | HOH609 |
| C | HOH621 |
| C | HOH830 |
| D | ASN306 |
| D | THR307 |
| D | HOH657 |
| D | HOH665 |
| site_id | AC8 |
| Number of Residues | 26 |
| Details | binding site for residues PLP D 501 and SEP D 502 |
| Chain | Residue |
| C | HIS110 |
| C | ARG111 |
| C | ASN306 |
| C | THR307 |
| C | HOH645 |
| C | HOH713 |
| D | ALA78 |
| D | GLY144 |
| D | ALA145 |
| D | THR146 |
| D | TRP171 |
| D | CYS217 |
| D | ASN219 |
| D | THR221 |
| D | ILE222 |
| D | ASP241 |
| D | SER243 |
| D | GLN264 |
| D | LYS265 |
| D | HIS396 |
| D | ARG397 |
| D | ARG403 |
| D | HOH605 |
| D | HOH633 |
| D | HOH639 |
| D | HOH824 |
| site_id | AC9 |
| Number of Residues | 23 |
| Details | binding site for Di-peptide PLP D 501 and LYS D 265 |
| Chain | Residue |
| C | ASN306 |
| C | THR307 |
| C | HOH645 |
| C | HOH713 |
| D | ALA78 |
| D | ALA81 |
| D | GLY144 |
| D | ALA145 |
| D | THR146 |
| D | TRP171 |
| D | CYS217 |
| D | ASN219 |
| D | THR221 |
| D | ASP241 |
| D | SER243 |
| D | ALA263 |
| D | GLN264 |
| D | ASN266 |
| D | TYR407 |
| D | SEP502 |
| D | HOH639 |
| D | HOH709 |
| D | HOH824 |
Functional Information from PROSITE/UniProt
| site_id | PS00595 |
| Number of Residues | 20 |
| Details | AA_TRANSFER_CLASS_5 Aminotransferases class-V pyridoxal-phosphate attachment site. FGVIygGAQKnvgps.GvTiV |
| Chain | Residue | Details |
| A | PHE256-VAL275 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 4 |
| Details | Binding site: {"evidences":[{"evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 20 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"30034403","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"6CZY","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6CZZ","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 4 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"30034403","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"6CZZ","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 4 |
| Details | Modified residue: {"description":"N6-(pyridoxal phosphate)lysine","evidences":[{"source":"PubMed","id":"30034403","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"6CZY","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6CZZ","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
