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6CYZ

Mycobacterial homoserine kinase ThrB in complex with AMPPNP

Functional Information from GO Data
ChainGOidnamespacecontents
A0004413molecular_functionhomoserine kinase activity
A0005524molecular_functionATP binding
A0005737cellular_componentcytoplasm
A0006566biological_processthreonine metabolic process
A0009088biological_processthreonine biosynthetic process
A0016301molecular_functionkinase activity
B0004413molecular_functionhomoserine kinase activity
B0005524molecular_functionATP binding
B0005737cellular_componentcytoplasm
B0006566biological_processthreonine metabolic process
B0009088biological_processthreonine biosynthetic process
B0016301molecular_functionkinase activity
Functional Information from PDB Data
site_idAC1
Number of Residues10
Detailsbinding site for residue ANP A 401
ChainResidue
AVAL60
AHOH570
AHIS66
AHIS96
ASER97
AGLY99
ASER102
ASER103
AALA106
AHOH544

site_idAC2
Number of Residues3
Detailsbinding site for residue CL A 402
ChainResidue
AMET245
APRO246
AALA247

site_idAC3
Number of Residues15
Detailsbinding site for residue ANP B 401
ChainResidue
BVAL60
BHIS66
BHIS96
BSER97
BARG98
BGLY99
BLEU100
BGLY101
BSER102
BSER103
BHOH504
BHOH509
BHOH529
BHOH539
BHOH551

Functional Information from PROSITE/UniProt
site_idPS00627
Number of Residues12
DetailsGHMP_KINASES_ATP GHMP kinases putative ATP-binding domain. IPhSrGLGSSAA
ChainResidueDetails
AILE94-ALA105

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues2
DetailsBINDING: BINDING => ECO:0000255|HAMAP-Rule:MF_00384
ChainResidueDetails
APRO95
BPRO95

227344

PDB entries from 2024-11-13

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