6CVH

Identification and biological evaluation of thiazole-based inverse agonists of RORgt

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003677	molecular_function	DNA binding
A	0004879	molecular_function	nuclear receptor activity
A	0005634	cellular_component	nucleus
A	0006355	biological_process	regulation of DNA-templated transcription

Functional Information from PDB Data

site_id	AC1
Number of Residues	13
Details	binding site for residue FJG A 501

Chain	Residue
A	GLN286
A	GLY380
A	PHE388
A	HIS479
A	LEU483
A	HIS323
A	LEU324
A	ALA327
A	MET358
A	VAL361
A	LEU362
A	PHE377
A	GLU379

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