Loading
PDBj
MenuPDBj@FacebookPDBj@X(formerly Twitter)PDBj@BlueSkyPDBj@YouTubewwPDB FoundationwwPDBDonate
RCSB PDBPDBeBMRBAdv. SearchSearch help

6CS9

Crystal structure of human beta-defensin 2 in complex with PIP2

Functional Information from GO Data
ChainGOidnamespacecontents
A0005515molecular_functionprotein binding
A0005546molecular_functionphosphatidylinositol-4,5-bisphosphate binding
A0005576cellular_componentextracellular region
A0005615cellular_componentextracellular space
A0005796cellular_componentGolgi lumen
A0006935biological_processchemotaxis
A0006952biological_processdefense response
A0006955biological_processimmune response
A0007186biological_processG protein-coupled receptor signaling pathway
A0031640biological_processkilling of cells of another organism
A0031731molecular_functionCCR6 chemokine receptor binding
A0042056molecular_functionchemoattractant activity
A0042742biological_processdefense response to bacterium
A0050829biological_processdefense response to Gram-negative bacterium
A0050830biological_processdefense response to Gram-positive bacterium
A0050832biological_processdefense response to fungus
A0050918biological_processpositive chemotaxis
A0060326biological_processcell chemotaxis
A0061760biological_processantifungal innate immune response
A0061844biological_processantimicrobial humoral immune response mediated by antimicrobial peptide
A0140546biological_processdefense response to symbiont
B0005515molecular_functionprotein binding
B0005546molecular_functionphosphatidylinositol-4,5-bisphosphate binding
B0005576cellular_componentextracellular region
B0005615cellular_componentextracellular space
B0005796cellular_componentGolgi lumen
B0006935biological_processchemotaxis
B0006952biological_processdefense response
B0006955biological_processimmune response
B0007186biological_processG protein-coupled receptor signaling pathway
B0031640biological_processkilling of cells of another organism
B0031731molecular_functionCCR6 chemokine receptor binding
B0042056molecular_functionchemoattractant activity
B0042742biological_processdefense response to bacterium
B0050829biological_processdefense response to Gram-negative bacterium
B0050830biological_processdefense response to Gram-positive bacterium
B0050832biological_processdefense response to fungus
B0050918biological_processpositive chemotaxis
B0060326biological_processcell chemotaxis
B0061760biological_processantifungal innate immune response
B0061844biological_processantimicrobial humoral immune response mediated by antimicrobial peptide
B0140546biological_processdefense response to symbiont
Functional Information from PDB Data
site_idAC1
Number of Residues16
Detailsbinding site for residue PIO A 101
ChainResidue
ALEU9
AHOH203
AHOH210
BPRO5
BLEU9
BLYS10
BPHE19
BARG22
ALYS10
ASER11
AGLY12
APHE19
AARG22
AARG23
ALYS25
AHOH201

site_idAC2
Number of Residues5
Detailsbinding site for residue PIO B 101
ChainResidue
ALEU32
ATHR35
BVAL18
BGLY34
BLYS36

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues80
DetailsPeptide: {"description":"Defensin beta 4A","featureId":"PRO_0000006968"}
ChainResidueDetails

site_idSWS_FT_FI2
Number of Residues30
DetailsRegion: {"description":"Phosphatidylinositol 4,5-bisphosphate (PIP2) binding","evidences":[{"source":"PubMed","id":"30050988","evidenceCode":"ECO:0000269"}]}
ChainResidueDetails

246704

PDB entries from 2025-12-24

PDB statisticsPDBj update infoContact PDBjnumon