Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003677 | molecular_function | DNA binding |
| A | 0003916 | molecular_function | DNA topoisomerase activity |
| A | 0003917 | molecular_function | DNA topoisomerase type I (single strand cut, ATP-independent) activity |
| A | 0006265 | biological_process | DNA topological change |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 3 |
| Details | binding site for residue FMT A 801 |
| Chain | Residue |
| A | ASP51 |
| A | LEU52 |
| A | ARG54 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | binding site for residue FMT A 802 |
| Chain | Residue |
| A | HIS48 |
| A | ARG50 |
| A | ASP51 |
| A | GLN164 |
| site_id | AC3 |
| Number of Residues | 6 |
| Details | binding site for residue GOL A 803 |
| Chain | Residue |
| A | TRP603 |
| A | PHE607 |
| A | SER618 |
| A | VAL619 |
| A | ARG576 |
| A | PHE582 |
| site_id | AC4 |
| Number of Residues | 4 |
| Details | binding site for residue ACT A 804 |
| Chain | Residue |
| A | ARG50 |
| A | TYR83 |
| A | TRP121 |
| A | GLU125 |
| site_id | AC5 |
| Number of Residues | 2 |
| Details | binding site for residue ACT A 805 |
| Chain | Residue |
| A | ASP76 |
| A | LYS626 |
| site_id | AC6 |
| Number of Residues | 2 |
| Details | binding site for residue ACT A 806 |
| Chain | Residue |
| A | SER317 |
| A | LYS552 |
Functional Information from PROSITE/UniProt
| site_id | PS00396 |
| Number of Residues | 15 |
| Details | TOPO_IA_1 Topoisomerase (Topo) IA-type active site signature. QrLYEngy.........ITYmRTD |
| Chain | Residue | Details |
| A | GLN332-ASP346 | |
Functional Information from SwissProt/UniProt
| Chain | Residue | Details |
| A | TYR342 | |
| Chain | Residue | Details |
| A | GLU24 | |
| A | ASP111 | |
| Chain | Residue | Details |
| A | HIS48 | |
| A | ARG167 | |
| A | ARG168 | |
| A | ASP171 | |
| A | TYR176 | |
| A | TRP183 | |
| A | ARG344 | |
| A | ARG547 | |
