6CE6
Structure of HDAC6 zinc-finger ubiquitin binding domain soaked with 3,3'-(benzo[1,2-d:5,4-d']bis(thiazole)-2,6-diyl)dipropionic acid
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0008270 | molecular_function | zinc ion binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 4 |
| Details | binding site for residue ZN A 1301 |
| Chain | Residue |
| A | CYS1145 |
| A | CYS1148 |
| A | HIS1164 |
| A | HIS1170 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | binding site for residue ZN A 1302 |
| Chain | Residue |
| A | CYS1133 |
| A | CYS1136 |
| A | CYS1153 |
| A | HIS1160 |
| site_id | AC3 |
| Number of Residues | 4 |
| Details | binding site for residue ZN A 1303 |
| Chain | Residue |
| A | HIS1115 |
| A | CYS1183 |
| A | CYS1186 |
| A | CYS1113 |
| site_id | AC4 |
| Number of Residues | 11 |
| Details | binding site for residue EYP A 1307 |
| Chain | Residue |
| A | TRP1143 |
| A | GLY1154 |
| A | ARG1155 |
| A | TRP1182 |
| A | TYR1184 |
| A | TYR1189 |
| A | HIS1203 |
| A | GLN1204 |
| A | HOH1410 |
| A | HOH1436 |
| A | HOH1444 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 9 |
| Details | Region: {"description":"Ubiquitin binding","evidences":[{"source":"Reference","evidenceCode":"ECO:0000269","citation":{"citationType":"submission","publicationDate":"APR-2009","submissionDatabase":"PDB data bank","title":"Crystal structure of human HDAC6 zinc finger domain and ubiquitin C-terminal peptide RLRGG.","authoringGroup":["Structural genomics consortium (SGC)"]}}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 12 |
| Details | Binding site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU00502","evidenceCode":"ECO:0000255"},{"source":"Reference","evidenceCode":"ECO:0000269","citation":{"citationType":"submission","publicationDate":"FEB-2008","submissionDatabase":"PDB data bank","title":"Crystal structure of human HDAC6 zinc finger domain.","authoringGroup":["Structural genomics consortium (SGC)"]}},{"source":"Reference","evidenceCode":"ECO:0000269","citation":{"citationType":"submission","publicationDate":"APR-2009","submissionDatabase":"PDB data bank","title":"Crystal structure of human HDAC6 zinc finger domain and ubiquitin C-terminal peptide RLRGG.","authoringGroup":["Structural genomics consortium (SGC)"]}}]} |
| Chain | Residue | Details |
