6CA1
THE CRYSTAL STRUCTURE OF THE W169Y MUTANT OF ALPHA-GLUCOSIDASE (GH 31) FROM RUMINOCOCCUS OBEUM ATCC 29174 in complex with miglitol
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003824 | molecular_function | catalytic activity |
| A | 0004553 | molecular_function | hydrolase activity, hydrolyzing O-glycosyl compounds |
| A | 0005975 | biological_process | carbohydrate metabolic process |
| A | 0016798 | molecular_function | hydrolase activity, acting on glycosyl bonds |
| A | 0030246 | molecular_function | carbohydrate binding |
| B | 0003824 | molecular_function | catalytic activity |
| B | 0004553 | molecular_function | hydrolase activity, hydrolyzing O-glycosyl compounds |
| B | 0005975 | biological_process | carbohydrate metabolic process |
| B | 0016798 | molecular_function | hydrolase activity, acting on glycosyl bonds |
| B | 0030246 | molecular_function | carbohydrate binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 15 |
| Details | binding site for residue MIG A 701 |
| Chain | Residue |
| A | TRP169 |
| A | ASP420 |
| A | PHE453 |
| A | HIS478 |
| A | HOH807 |
| A | HOH903 |
| A | HOH1035 |
| A | ASP197 |
| A | ILE198 |
| A | TRP271 |
| A | TRP305 |
| A | ASP307 |
| A | MET308 |
| A | ARG404 |
| A | TRP417 |
| site_id | AC2 |
| Number of Residues | 6 |
| Details | binding site for residue GOL A 702 |
| Chain | Residue |
| A | ASN561 |
| A | ARG563 |
| A | HOH1002 |
| B | GLU46 |
| B | ARG63 |
| B | HOH881 |
| site_id | AC3 |
| Number of Residues | 15 |
| Details | binding site for residue MIG B 701 |
| Chain | Residue |
| B | TRP169 |
| B | ASP197 |
| B | ILE198 |
| B | TRP271 |
| B | TRP305 |
| B | ASP307 |
| B | MET308 |
| B | ARG404 |
| B | TRP417 |
| B | ASP420 |
| B | PHE453 |
| B | HIS478 |
| B | HOH806 |
| B | HOH879 |
| B | HOH1061 |
| site_id | AC4 |
| Number of Residues | 6 |
| Details | binding site for residue GOL B 702 |
| Chain | Residue |
| A | GLU46 |
| A | ARG63 |
| A | HOH956 |
| B | ASN561 |
| B | ARG563 |
| B | HOH886 |
Functional Information from PROSITE/UniProt
| site_id | PS00129 |
| Number of Residues | 8 |
| Details | GLYCOSYL_HYDROL_F31_1 Glycosyl hydrolases family 31 active site. GFWnDMNE |
| Chain | Residue | Details |
| A | GLY303-GLU310 |
