Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 2 |
| Details | binding site for residue EDO A 601 |
| Chain | Residue |
| A | ASN464 |
| A | ALA465 |
| site_id | AC2 |
| Number of Residues | 7 |
| Details | binding site for residue EDO A 602 |
| Chain | Residue |
| A | SER284 |
| A | CYS288 |
| A | ARG392 |
| A | VAL394 |
| A | EDO605 |
| A | HOH703 |
| B | PRO246 |
| site_id | AC3 |
| Number of Residues | 1 |
| Details | binding site for residue EDO A 603 |
| site_id | AC4 |
| Number of Residues | 3 |
| Details | binding site for residue EDO A 604 |
| Chain | Residue |
| A | TYR399 |
| A | HOH706 |
| A | HOH748 |
| site_id | AC5 |
| Number of Residues | 7 |
| Details | binding site for residue EDO A 605 |
| Chain | Residue |
| A | GLU338 |
| A | VAL394 |
| A | PRO395 |
| A | EDO602 |
| A | HOH815 |
| B | GLU338 |
| B | PRO395 |
| site_id | AC6 |
| Number of Residues | 2 |
| Details | binding site for residue EDO A 606 |
| Chain | Residue |
| A | ARG238 |
| A | HOH874 |
| site_id | AC7 |
| Number of Residues | 2 |
| Details | binding site for residue EDO A 607 |
| Chain | Residue |
| A | LEU275 |
| A | ASP321 |
| site_id | AC8 |
| Number of Residues | 3 |
| Details | binding site for residue CL A 608 |
| Chain | Residue |
| A | ARG392 |
| A | HOH848 |
| B | ARG437 |
| site_id | AC9 |
| Number of Residues | 5 |
| Details | binding site for residue CL A 609 |
| Chain | Residue |
| A | ARG437 |
| A | HOH787 |
| A | HOH890 |
| B | ARG392 |
| B | HOH780 |
| site_id | AD1 |
| Number of Residues | 6 |
| Details | binding site for residue MG A 610 |
| Chain | Residue |
| A | ASP366 |
| A | ASP410 |
| A | HOH739 |
| A | HOH763 |
| A | HOH826 |
| A | HOH871 |
| site_id | AD2 |
| Number of Residues | 6 |
| Details | binding site for residue MG A 611 |
| Chain | Residue |
| A | GLN438 |
| A | ASP440 |
| A | HOH732 |
| A | HOH757 |
| A | HOH768 |
| A | HOH830 |
| site_id | AD3 |
| Number of Residues | 4 |
| Details | binding site for residue EDO B 601 |
| Chain | Residue |
| B | MET229 |
| B | ASP231 |
| B | ASN464 |
| B | HOH781 |
| site_id | AD4 |
| Number of Residues | 2 |
| Details | binding site for residue EDO B 602 |
| Chain | Residue |
| B | HOH783 |
| B | HOH874 |
| site_id | AD5 |
| Number of Residues | 4 |
| Details | binding site for residue EDO B 603 |
| Chain | Residue |
| A | ARG396 |
| B | THR353 |
| B | THR354 |
| B | VAL378 |
| site_id | AD6 |
| Number of Residues | 4 |
| Details | binding site for residue EDO B 604 |
| Chain | Residue |
| B | GLY300 |
| B | THR301 |
| B | GLY302 |
| B | ALA380 |
| site_id | AD7 |
| Number of Residues | 5 |
| Details | binding site for residue EDO B 605 |
| Chain | Residue |
| B | GLY400 |
| B | HOH798 |
| B | HOH812 |
| B | HOH830 |
| D | VAL39 |
| site_id | AD8 |
| Number of Residues | 7 |
| Details | binding site for residue EDO B 606 |
| Chain | Residue |
| A | GLU456 |
| A | SER459 |
| A | TRP460 |
| B | GLU456 |
| B | SER459 |
| B | TRP460 |
| B | HOH702 |
| site_id | AD9 |
| Number of Residues | 6 |
| Details | binding site for residue MG B 607 |
| Chain | Residue |
| B | ASP366 |
| B | ASP410 |
| B | HOH760 |
| B | HOH771 |
| B | HOH843 |
| B | HOH878 |
| site_id | AE1 |
| Number of Residues | 6 |
| Details | binding site for residue MG B 608 |
| Chain | Residue |
| B | GLN438 |
| B | ASP440 |
| B | HOH747 |
| B | HOH758 |
| B | HOH776 |
| B | HOH801 |
| site_id | AE2 |
| Number of Residues | 6 |
| Details | binding site for residue EDO D 201 |
| Chain | Residue |
| B | THR362 |
| B | THR363 |
| B | ASN364 |
| D | CYS36 |
| D | CYS44 |
| D | THR46 |
| site_id | AE3 |
| Number of Residues | 2 |
| Details | binding site for residue EDO D 202 |
| Chain | Residue |
| D | TYR31 |
| D | HOH327 |
| site_id | AE4 |
| Number of Residues | 8 |
| Details | binding site for residue EDO D 203 |
| Chain | Residue |
| D | GLN37 |
| D | GLY38 |
| D | SER83 |
| D | ALA85 |
| D | ILE87 |
| D | TYR88 |
| D | HOH337 |
| D | HOH338 |
| site_id | AE5 |
| Number of Residues | 3 |
| Details | binding site for residue EDO D 204 |
| Chain | Residue |
| D | THR46 |
| D | LYS59 |
| D | LYS45 |
| site_id | AE6 |
| Number of Residues | 5 |
| Details | binding site for residue EDO D 205 |
| Chain | Residue |
| B | GLY300 |
| D | GLN41 |
| D | ARG42 |
| D | MET100 |
| D | HOH303 |
| site_id | AE7 |
| Number of Residues | 4 |
| Details | binding site for residue EDO D 206 |
| Chain | Residue |
| A | PRO425 |
| D | HOH310 |
| D | HOH332 |
| D | HOH349 |
| site_id | AE8 |
| Number of Residues | 6 |
| Details | binding site for residue MG D 207 |
| Chain | Residue |
| B | ASN364 |
| B | ASP366 |
| B | HOH899 |
| D | LYS94 |
| D | GLY96 |
| D | ASP98 |
| site_id | AE9 |
| Number of Residues | 7 |
| Details | binding site for residue EDO F 201 |
| Chain | Residue |
| B | PRO522 |
| F | GLY12 |
| F | GLN13 |
| F | GLY16 |
| F | SER17 |
| F | LEU80 |
| F | HOH321 |
| site_id | AF1 |
| Number of Residues | 6 |
| Details | binding site for residue EDO F 202 |
| Chain | Residue |
| A | SER377 |
| A | HOH747 |
| F | GLN41 |
| F | ARG42 |
| F | HOH301 |
| F | HOH320 |
| site_id | AF2 |
| Number of Residues | 4 |
| Details | binding site for residue EDO F 203 |
| Chain | Residue |
| F | THR104 |
| F | VAL105 |
| F | ASN106 |
| F | HOH305 |
| site_id | AF3 |
| Number of Residues | 6 |
| Details | binding site for residue MG F 204 |
| Chain | Residue |
| A | ASN364 |
| A | ASP366 |
| A | HOH896 |
| F | LYS94 |
| F | GLY96 |
| F | ASP98 |
