6C6B

Co-crystal structure of adenylyl-sulfate kinase from Cryptococcus neoformans bound to ADP

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000103	biological_process	sulfate assimilation
A	0000166	molecular_function	nucleotide binding
A	0004020	molecular_function	adenylylsulfate kinase activity
A	0005524	molecular_function	ATP binding
A	0016301	molecular_function	kinase activity
A	0016740	molecular_function	transferase activity
A	0019344	biological_process	cysteine biosynthetic process
A	0070814	biological_process	hydrogen sulfide biosynthetic process
B	0000103	biological_process	sulfate assimilation
B	0000166	molecular_function	nucleotide binding
B	0004020	molecular_function	adenylylsulfate kinase activity
B	0005524	molecular_function	ATP binding
B	0016301	molecular_function	kinase activity
B	0016740	molecular_function	transferase activity
B	0019344	biological_process	cysteine biosynthetic process
B	0070814	biological_process	hydrogen sulfide biosynthetic process
C	0000103	biological_process	sulfate assimilation
C	0000166	molecular_function	nucleotide binding
C	0004020	molecular_function	adenylylsulfate kinase activity
C	0005524	molecular_function	ATP binding
C	0016301	molecular_function	kinase activity
C	0016740	molecular_function	transferase activity
C	0019344	biological_process	cysteine biosynthetic process
C	0070814	biological_process	hydrogen sulfide biosynthetic process
D	0000103	biological_process	sulfate assimilation
D	0000166	molecular_function	nucleotide binding
D	0004020	molecular_function	adenylylsulfate kinase activity
D	0005524	molecular_function	ATP binding
D	0016301	molecular_function	kinase activity
D	0016740	molecular_function	transferase activity
D	0019344	biological_process	cysteine biosynthetic process
D	0070814	biological_process	hydrogen sulfide biosynthetic process
E	0000103	biological_process	sulfate assimilation
E	0000166	molecular_function	nucleotide binding
E	0004020	molecular_function	adenylylsulfate kinase activity
E	0005524	molecular_function	ATP binding
E	0016301	molecular_function	kinase activity
E	0016740	molecular_function	transferase activity
E	0019344	biological_process	cysteine biosynthetic process
E	0070814	biological_process	hydrogen sulfide biosynthetic process
F	0000103	biological_process	sulfate assimilation
F	0000166	molecular_function	nucleotide binding
F	0004020	molecular_function	adenylylsulfate kinase activity
F	0005524	molecular_function	ATP binding
F	0016301	molecular_function	kinase activity
F	0016740	molecular_function	transferase activity
F	0019344	biological_process	cysteine biosynthetic process
F	0070814	biological_process	hydrogen sulfide biosynthetic process

Functional Information from PDB Data

site_id	AC1
Number of Residues	16
Details	binding site for residue ADP A 300

Chain	Residue
A	LEU33
A	VAL182
A	ASP183
A	VAL184
A	HOH410
A	HOH423
A	HOH428
D	ALA203
A	ALA35
A	SER36
A	GLY37
A	LYS38
A	SER39
A	THR40
A	ARG143
A	THR179

---

site_id	AC2
Number of Residues	2
Details	binding site for residue EDO A 301

Chain	Residue
A	GLU120
A	PHE128

---

site_id	AC3
Number of Residues	16
Details	binding site for residue ADP B 300

Chain	Residue
B	LEU33
B	ALA35
B	SER36
B	GLY37
B	LYS38
B	SER39
B	THR40
B	ARG143
B	THR179
B	VAL182
B	ASP183
B	VAL184
B	HOH423
B	HOH440
B	HOH467
B	HOH472

---

site_id	AC4
Number of Residues	3
Details	binding site for residue EDO B 301

Chain	Residue
B	GLU120
B	PHE128
B	GLU174

---

site_id	AC5
Number of Residues	4
Details	binding site for residue EDO B 302

Chain	Residue
B	VAL80
B	GLU81
B	ARG84
B	HOH465

---

site_id	AC6
Number of Residues	16
Details	binding site for residue ADP C 300

Chain	Residue
A	ALA203
C	LEU33
C	ALA35
C	SER36
C	GLY37
C	LYS38
C	SER39
C	THR40
C	ILE41
C	ARG143
C	THR179
C	VAL182
C	ASP183
C	HOH416
C	HOH426
C	HOH427

---

site_id	AC7
Number of Residues	14
Details	binding site for residue ADP D 300

Chain	Residue
D	LEU33
D	ALA35
D	SER36
D	GLY37
D	LYS38
D	SER39
D	THR40
D	ARG143
D	THR179
D	VAL182
D	ASP183
D	VAL184
D	HOH403
D	HOH422

---

site_id	AC8
Number of Residues	10
Details	binding site for residue ADP E 300

Chain	Residue
E	LEU33
E	ALA35
E	SER36
E	GLY37
E	LYS38
E	SER39
E	THR40
E	THR179
E	VAL182
E	VAL184

---

site_id	AC9
Number of Residues	15
Details	binding site for residue ADP F 300

Chain	Residue
F	LEU33
F	ALA35
F	SER36
F	GLY37
F	LYS38
F	SER39
F	THR40
F	ARG143
F	THR179
F	VAL182
F	ASP183
F	VAL184
F	HOH403
F	HOH407
F	HOH408

---