6C4H
Conformation of methylated GGQ in the peptidyl transferase center during translation termination (PTC region)
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| C | 0000027 | biological_process | ribosomal large subunit assembly |
| C | 0002181 | biological_process | cytoplasmic translation |
| C | 0003723 | molecular_function | RNA binding |
| C | 0003735 | molecular_function | structural constituent of ribosome |
| C | 0005515 | molecular_function | protein binding |
| C | 0005737 | cellular_component | cytoplasm |
| C | 0005829 | cellular_component | cytosol |
| C | 0005840 | cellular_component | ribosome |
| C | 0006412 | biological_process | translation |
| C | 0008270 | molecular_function | zinc ion binding |
| C | 0015934 | cellular_component | large ribosomal subunit |
| C | 0016740 | molecular_function | transferase activity |
| C | 0019843 | molecular_function | rRNA binding |
| C | 0022625 | cellular_component | cytosolic large ribosomal subunit |
| C | 0032297 | biological_process | negative regulation of DNA-templated DNA replication initiation |
| C | 1990082 | cellular_component | DnaA-L2 complex |
| C | 1990904 | cellular_component | ribonucleoprotein complex |
| D | 0000027 | biological_process | ribosomal large subunit assembly |
| D | 0002181 | biological_process | cytoplasmic translation |
| D | 0003723 | molecular_function | RNA binding |
| D | 0003735 | molecular_function | structural constituent of ribosome |
| D | 0005515 | molecular_function | protein binding |
| D | 0005737 | cellular_component | cytoplasm |
| D | 0005829 | cellular_component | cytosol |
| D | 0005840 | cellular_component | ribosome |
| D | 0006412 | biological_process | translation |
| D | 0019843 | molecular_function | rRNA binding |
| D | 0022625 | cellular_component | cytosolic large ribosomal subunit |
| D | 1990904 | cellular_component | ribonucleoprotein complex |
| N | 0000027 | biological_process | ribosomal large subunit assembly |
| N | 0000049 | molecular_function | tRNA binding |
| N | 0002181 | biological_process | cytoplasmic translation |
| N | 0003723 | molecular_function | RNA binding |
| N | 0003735 | molecular_function | structural constituent of ribosome |
| N | 0005737 | cellular_component | cytoplasm |
| N | 0005840 | cellular_component | ribosome |
| N | 0006412 | biological_process | translation |
| N | 0019843 | molecular_function | rRNA binding |
| N | 0022625 | cellular_component | cytosolic large ribosomal subunit |
| N | 1990904 | cellular_component | ribonucleoprotein complex |
| X | 0000027 | biological_process | ribosomal large subunit assembly |
| X | 0000049 | molecular_function | tRNA binding |
| X | 0001558 | biological_process | regulation of cell growth |
| X | 0002181 | biological_process | cytoplasmic translation |
| X | 0003723 | molecular_function | RNA binding |
| X | 0003735 | molecular_function | structural constituent of ribosome |
| X | 0005515 | molecular_function | protein binding |
| X | 0005737 | cellular_component | cytoplasm |
| X | 0005840 | cellular_component | ribosome |
| X | 0006412 | biological_process | translation |
| X | 0019843 | molecular_function | rRNA binding |
| X | 0022625 | cellular_component | cytosolic large ribosomal subunit |
| X | 0042256 | biological_process | cytosolic ribosome assembly |
| X | 0043022 | molecular_function | ribosome binding |
| X | 0090070 | biological_process | positive regulation of ribosome biogenesis |
| X | 1902626 | biological_process | assembly of large subunit precursor of preribosome |
| X | 1990904 | cellular_component | ribonucleoprotein complex |
| v | 0003747 | molecular_function | translation release factor activity |
| v | 0005737 | cellular_component | cytoplasm |
| v | 0005829 | cellular_component | cytosol |
| v | 0006412 | biological_process | translation |
| v | 0006415 | biological_process | translational termination |
| v | 0016149 | molecular_function | translation release factor activity, codon specific |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 4 |
| Details | binding site for residue MG A 3001 |
| Chain | Residue |
| A | A739 |
| A | U1778 |
| A | U1779 |
| A | A1784 |
| site_id | AC2 |
| Number of Residues | 3 |
| Details | binding site for residue MG A 3002 |
| Chain | Residue |
| A | C740 |
| A | A1783 |
| A | A1784 |
| site_id | AC3 |
| Number of Residues | 3 |
| Details | binding site for residue MG A 3003 |
| Chain | Residue |
| A | C946 |
| A | C944 |
| A | A945 |
| site_id | AC4 |
| Number of Residues | 1 |
| Details | binding site for residue MG A 3004 |
| Chain | Residue |
| A | A945 |
| site_id | AC5 |
| Number of Residues | 3 |
| Details | binding site for residue MG A 3005 |
| Chain | Residue |
| A | C948 |
| A | G962 |
| A | U963 |
| site_id | AC6 |
| Number of Residues | 3 |
| Details | binding site for residue MG A 3006 |
| Chain | Residue |
| A | A1664 |
| A | A1665 |
| A | G1992 |
| site_id | AC7 |
| Number of Residues | 2 |
| Details | binding site for residue MG A 3007 |
| Chain | Residue |
| A | C1670 |
| A | U1671 |
| site_id | AC8 |
| Number of Residues | 3 |
| Details | binding site for residue MG A 3008 |
| Chain | Residue |
| A | A1672 |
| A | G1673 |
| A | OMU2552 |
| site_id | AC9 |
| Number of Residues | 1 |
| Details | binding site for residue MG A 3009 |
| Chain | Residue |
| A | A1676 |
| site_id | AD1 |
| Number of Residues | 1 |
| Details | binding site for residue MG A 3010 |
| Chain | Residue |
| A | A1678 |
| site_id | AD2 |
| Number of Residues | 3 |
| Details | binding site for residue MG A 3011 |
| Chain | Residue |
| A | A1780 |
| A | U1782 |
| A | A1783 |
| site_id | AD3 |
| Number of Residues | 1 |
| Details | binding site for residue MG A 3012 |
| Chain | Residue |
| A | A1938 |
| site_id | AD4 |
| Number of Residues | 3 |
| Details | binding site for residue MG A 3013 |
| Chain | Residue |
| A | 2MG1835 |
| A | A1900 |
| A | A1970 |
| site_id | AD5 |
| Number of Residues | 2 |
| Details | binding site for residue MG A 3014 |
| Chain | Residue |
| A | U2028 |
| A | A2033 |
| site_id | AD6 |
| Number of Residues | 2 |
| Details | binding site for residue MG A 3015 |
| Chain | Residue |
| A | G2056 |
| A | G2057 |
| site_id | AD7 |
| Number of Residues | 2 |
| Details | binding site for residue MG A 3016 |
| Chain | Residue |
| A | G2061 |
| A | G2502 |
| site_id | AD8 |
| Number of Residues | 2 |
| Details | binding site for residue MG A 3017 |
| Chain | Residue |
| A | U2074 |
| A | G2239 |
| site_id | AD9 |
| Number of Residues | 3 |
| Details | binding site for residue MG A 3018 |
| Chain | Residue |
| A | C2066 |
| A | C2248 |
| A | U2249 |
| site_id | AE1 |
| Number of Residues | 5 |
| Details | binding site for residue MG A 3019 |
| Chain | Residue |
| A | G2447 |
| A | A2448 |
| A | A2497 |
| A | OMC2498 |
| A | C2499 |
| site_id | AE2 |
| Number of Residues | 2 |
| Details | binding site for residue MG A 3020 |
| Chain | Residue |
| A | A2448 |
| A | C2499 |
| site_id | AE3 |
| Number of Residues | 1 |
| Details | binding site for residue MG A 3021 |
| Chain | Residue |
| A | A2518 |
| site_id | AE4 |
| Number of Residues | 5 |
| Details | binding site for residue MG A 3022 |
| Chain | Residue |
| A | A2052 |
| A | G2053 |
| A | C2575 |
| A | G2576 |
| A | A2577 |
| site_id | AE5 |
| Number of Residues | 3 |
| Details | binding site for residue MG A 3023 |
| Chain | Residue |
| A | G2581 |
| A | G2582 |
| A | G2583 |
| site_id | AE6 |
| Number of Residues | 2 |
| Details | binding site for residue MG A 3024 |
| Chain | Residue |
| A | G784 |
| A | G2588 |
| site_id | AE7 |
| Number of Residues | 4 |
| Details | binding site for residue MG A 3025 |
| Chain | Residue |
| A | A783 |
| A | G784 |
| A | A2589 |
| C | ALA224 |
| site_id | AE8 |
| Number of Residues | 1 |
| Details | binding site for residue MG A 3026 |
| Chain | Residue |
| A | U963 |
| site_id | AE9 |
| Number of Residues | 1 |
| Details | binding site for residue MG A 3027 |
| Chain | Residue |
| A | G1776 |
| site_id | AF1 |
| Number of Residues | 2 |
| Details | binding site for residue MG A 3028 |
| Chain | Residue |
| A | A1970 |
| A | U1971 |
| site_id | AF2 |
| Number of Residues | 1 |
| Details | binding site for residue MG A 3029 |
| Chain | Residue |
| A | C2025 |
| site_id | AF3 |
| Number of Residues | 2 |
| Details | binding site for residue MG A 3030 |
| Chain | Residue |
| A | A2270 |
| A | U2272 |
| site_id | AF4 |
| Number of Residues | 2 |
| Details | binding site for residue MG A 3031 |
| Chain | Residue |
| A | G2588 |
| C | GLU236 |
| site_id | AF5 |
| Number of Residues | 3 |
| Details | binding site for residue MG A 3032 |
| Chain | Residue |
| A | U2506 |
| A | C2507 |
| A | G2576 |
| site_id | AF6 |
| Number of Residues | 3 |
| Details | binding site for residue MG A 3034 |
| Chain | Residue |
| A | C787 |
| A | U790 |
| A | C791 |
Functional Information from PROSITE/UniProt
| site_id | PS00474 |
| Number of Residues | 24 |
| Details | RIBOSOMAL_L3 Ribosomal protein L3 signature. FadvkkvDvtGtSkGKGfaGtvkR |
| Chain | Residue | Details |
| D | PHE101-ARG124 |
| site_id | PS00467 |
| Number of Residues | 12 |
| Details | RIBOSOMAL_L2 Ribosomal protein L2 signature. PtvRGTAmNPvD |
| Chain | Residue | Details |
| C | PRO218-ASP229 |
| site_id | PS00586 |
| Number of Residues | 12 |
| Details | RIBOSOMAL_L16_1 Ribosomal protein L16 signature 1. KRqGKIWIRVFP |
| Chain | Residue | Details |
| N | LYS58-PRO69 |
| site_id | PS00701 |
| Number of Residues | 12 |
| Details | RIBOSOMAL_L16_2 Ribosomal protein L16 signature 2. RMGkGKGnveyW |
| Chain | Residue | Details |
| N | ARG81-TRP92 |
| site_id | PS00745 |
| Number of Residues | 17 |
| Details | RF_PROK_I Prokaryotic-type class I peptide chain release factors signature. RTsGaGGQHVNrteSAV |
| Chain | Residue | Details |
| v | ARG245-VAL261 |
| site_id | PS00831 |
| Number of Residues | 15 |
| Details | RIBOSOMAL_L27 Ribosomal protein L27 signature. GsIIvRQRGtkfhaG |
| Chain | Residue | Details |
| X | GLY34-GLY48 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 1 |
| Details | MOD_RES: N5-methylglutamine => ECO:0000269|PubMed:11118225, ECO:0000269|PubMed:11847124, ECO:0000269|PubMed:28077875 |
| Chain | Residue | Details |
| v | MEQ252 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 1 |
| Details | MOD_RES: (3R)-3-hydroxyarginine => ECO:0000269|PubMed:23103944 |
| Chain | Residue | Details |
| N | ARG81 |
