6C3I
Crystal structure of the Deinococcus radiodurans Nramp/MntH divalent transition metal transporter G45R mutant in an inward occluded state
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005384 | molecular_function | manganese ion transmembrane transporter activity |
| A | 0005886 | cellular_component | plasma membrane |
| A | 0006811 | biological_process | monoatomic ion transport |
| A | 0006828 | biological_process | manganese ion transport |
| A | 0006879 | biological_process | intracellular iron ion homeostasis |
| A | 0015293 | molecular_function | symporter activity |
| A | 0016020 | cellular_component | membrane |
| A | 0030001 | biological_process | metal ion transport |
| A | 0030026 | biological_process | intracellular manganese ion homeostasis |
| A | 0034755 | biological_process | iron ion transmembrane transport |
| A | 0046872 | molecular_function | metal ion binding |
| A | 0046873 | molecular_function | metal ion transmembrane transporter activity |
| A | 0071421 | biological_process | manganese ion transmembrane transport |
| B | 0005384 | molecular_function | manganese ion transmembrane transporter activity |
| B | 0005886 | cellular_component | plasma membrane |
| B | 0006811 | biological_process | monoatomic ion transport |
| B | 0006828 | biological_process | manganese ion transport |
| B | 0006879 | biological_process | intracellular iron ion homeostasis |
| B | 0015293 | molecular_function | symporter activity |
| B | 0016020 | cellular_component | membrane |
| B | 0030001 | biological_process | metal ion transport |
| B | 0030026 | biological_process | intracellular manganese ion homeostasis |
| B | 0034755 | biological_process | iron ion transmembrane transport |
| B | 0046872 | molecular_function | metal ion binding |
| B | 0046873 | molecular_function | metal ion transmembrane transporter activity |
| B | 0071421 | biological_process | manganese ion transmembrane transport |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 8 |
| Details | binding site for residue OLC A 501 |
| Chain | Residue |
| A | LEU83 |
| A | MET86 |
| A | VAL87 |
| A | ASN90 |
| A | ARG261 |
| A | PHE411 |
| A | ILE418 |
| A | ILE421 |
| site_id | AC2 |
| Number of Residues | 2 |
| Details | binding site for residue OLC A 502 |
| Chain | Residue |
| A | OLC504 |
| A | TRP416 |
| site_id | AC3 |
| Number of Residues | 6 |
| Details | binding site for residue OLC A 503 |
| Chain | Residue |
| A | TRP111 |
| A | LEU115 |
| A | TYR119 |
| A | LEU201 |
| A | PHE387 |
| A | VAL390 |
| site_id | AC4 |
| Number of Residues | 6 |
| Details | binding site for residue OLC A 504 |
| Chain | Residue |
| A | LEU191 |
| A | VAL194 |
| A | LEU201 |
| A | VAL204 |
| A | LEU273 |
| A | OLC502 |
| site_id | AC5 |
| Number of Residues | 4 |
| Details | binding site for residue OLC B 501 |
| Chain | Residue |
| B | LEU191 |
| B | VAL194 |
| B | PRO199 |
| B | VAL204 |
| site_id | AC6 |
| Number of Residues | 10 |
| Details | binding site for residue OLC B 502 |
| Chain | Residue |
| B | ARG110 |
| B | TRP111 |
| B | TYR119 |
| B | LEU201 |
| B | PHE383 |
| B | PRO386 |
| B | VAL390 |
| B | ILE423 |
| B | ASN426 |
| B | HOH602 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 400 |
| Details | Transmembrane: {"description":"Helical","evidences":[{"source":"HAMAP-Rule","id":"MF_00221","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
