Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004190 | molecular_function | aspartic-type endopeptidase activity |
| A | 0006508 | biological_process | proteolysis |
| A | 0016020 | cellular_component | membrane |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 3 |
| Details | binding site for residue IOD A 401 |
| Chain | Residue |
| A | GLU103 |
| A | SER104 |
| A | HOH787 |
| site_id | AC2 |
| Number of Residues | 1 |
| Details | binding site for residue IOD A 402 |
| site_id | AC3 |
| Number of Residues | 9 |
| Details | binding site for residue GOL A 404 |
| Chain | Residue |
| A | HOH525 |
| A | HOH561 |
| A | HOH571 |
| A | HOH726 |
| A | ARG49 |
| A | TYR50 |
| A | GLN52 |
| A | SER186 |
| A | HOH514 |
| site_id | AC4 |
| Number of Residues | 7 |
| Details | binding site for residue GOL A 405 |
| Chain | Residue |
| A | GLY65 |
| A | TYR67 |
| A | CYS268 |
| A | THR313 |
| A | HOH501 |
| A | HOH555 |
| A | HOH638 |
| site_id | AC5 |
| Number of Residues | 6 |
| Details | binding site for residue SO4 A 406 |
| Chain | Residue |
| A | ARG53 |
| A | GLN54 |
| A | ASP345 |
| A | ARG348 |
| A | ARG350 |
| A | HOH570 |
| site_id | AC6 |
| Number of Residues | 14 |
| Details | binding site for residue EJ7 A 407 |
| Chain | Residue |
| A | GLY10 |
| A | GLN11 |
| A | GLY12 |
| A | LEU29 |
| A | ASP31 |
| A | TYR70 |
| A | PHE107 |
| A | ILE117 |
| A | ASP227 |
| A | SER228 |
| A | GLY229 |
| A | THR231 |
| A | ALA334 |
| A | HOH628 |
Functional Information from PROSITE/UniProt
| site_id | PS00141 |
| Number of Residues | 12 |
| Details | ASP_PROTEASE Eukaryotic and viral aspartyl proteases active site. ILVDTGSSNFAV |
| Chain | Residue | Details |
| A | ILE28-VAL39 | |
Functional Information from SwissProt/UniProt
| Chain | Residue | Details |
| A | ASP31 | |
| A | ASP227 | |
| Chain | Residue | Details |
| A | LYS64 | |
| A | LYS213 | |
| A | LYS217 | |
| A | LYS223 | |
| A | LYS237 | |
| A | LYS238 | |
| A | LYS245 | |
| site_id | SWS_FT_FI3 |
| Number of Residues | 4 |
| Details | CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000255 |
| Chain | Residue | Details |
| A | ASN91 | |
| A | ASN110 | |
| A | ASN161 | |
| A | ASN292 | |
