Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0016301 | molecular_function | kinase activity |
| A | 0046854 | biological_process | phosphatidylinositol phosphate biosynthetic process |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 16 |
| Details | binding site for residue EFV A 1201 |
| Chain | Residue |
| A | TRP812 |
| A | VAL882 |
| A | LYS883 |
| A | ALA885 |
| A | MET953 |
| A | ILE963 |
| A | ASP964 |
| A | HOH1308 |
| A | ILE831 |
| A | LYS833 |
| A | ASP836 |
| A | ASP841 |
| A | TYR867 |
| A | ILE879 |
| A | GLU880 |
| A | ILE881 |
| site_id | AC2 |
| Number of Residues | 6 |
| Details | binding site for residue SO4 A 1202 |
| Chain | Residue |
| A | PRO206 |
| A | LEU207 |
| A | TRP212 |
| A | LYS288 |
| A | LYS1066 |
| A | HOH1373 |
| site_id | AC3 |
| Number of Residues | 6 |
| Details | binding site for residue SO4 A 1203 |
| Chain | Residue |
| A | ASP946 |
| A | ARG947 |
| A | HIS948 |
| A | ASN951 |
| A | ILE968 |
| A | TRP1086 |
| site_id | AC4 |
| Number of Residues | 6 |
| Details | binding site for residue SO4 A 1204 |
| Chain | Residue |
| A | ALA545 |
| A | GLU546 |
| A | TRP576 |
| A | ARG579 |
| A | LYS606 |
| A | HOH1305 |
| site_id | AC5 |
| Number of Residues | 4 |
| Details | binding site for residue SO4 A 1205 |
| Chain | Residue |
| A | LEU657 |
| A | PHE694 |
| A | PHE698 |
| A | GLN846 |
Functional Information from PROSITE/UniProt
| site_id | PS00915 |
| Number of Residues | 15 |
| Details | PI3_4_KINASE_1 Phosphatidylinositol 3- and 4-kinases signature 1. FKhg.DDLRQDmlilQ |
| Chain | Residue | Details |
| A | PHE832-GLN846 | |
| site_id | PS00916 |
| Number of Residues | 21 |
| Details | PI3_4_KINASE_2 Phosphatidylinositol 3- and 4-kinases signature 2. ScAgycVatFVLgIgDRHndN |
| Chain | Residue | Details |
| A | SER931-ASN951 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 6 |
| Details | Region: {"description":"G-loop","evidences":[{"source":"PROSITE-ProRule","id":"PRU00269","evidenceCode":"ECO:0000255"}]} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 8 |
| Details | Region: {"description":"Catalytic loop","evidences":[{"source":"PROSITE-ProRule","id":"PRU00269","evidenceCode":"ECO:0000255"}]} |
| site_id | SWS_FT_FI3 |
| Number of Residues | 17 |
| Details | Binding site: {"evidences":[{"evidenceCode":"ECO:0000250"}]} |
| site_id | SWS_FT_FI4 |
| Number of Residues | 1 |
| Details | Modified residue: {"description":"Phosphothreonine; by PKA","evidences":[{"source":"UniProtKB","id":"Q9JHG7","evidenceCode":"ECO:0000250"}]} |
