6BYO
Residue assignment correction to the voltage gated calcium Cav1.1 rabbit alpha 1 subunit PDB entries 3JBR & 5GJV
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005216 | molecular_function | monoatomic ion channel activity |
| A | 0005245 | molecular_function | voltage-gated calcium channel activity |
| A | 0005891 | cellular_component | voltage-gated calcium channel complex |
| A | 0006811 | biological_process | monoatomic ion transport |
| A | 0016020 | cellular_component | membrane |
| A | 0055085 | biological_process | transmembrane transport |
| A | 0070588 | biological_process | calcium ion transmembrane transport |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 18 |
| Details | Transmembrane: {"description":"Helical; Name=S1 of repeat I","evidences":[{"source":"PubMed","id":"27580036","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 256 |
| Details | Topological domain: {"description":"Extracellular","evidences":[{"source":"PubMed","id":"27580036","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 20 |
| Details | Transmembrane: {"description":"Helical; Name=S2 of repeat I","evidences":[{"source":"PubMed","id":"27580036","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 18 |
| Details | Transmembrane: {"description":"Helical; Name=S4 of repeat I","evidences":[{"source":"PubMed","id":"27580036","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 145 |
| Details | Topological domain: {"description":"Cytoplasmic","evidences":[{"source":"PubMed","id":"27580036","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI6 |
| Number of Residues | 21 |
| Details | Transmembrane: {"description":"Helical; Name=S5 of repeat I","evidences":[{"source":"PubMed","id":"27580036","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI7 |
| Number of Residues | 80 |
| Details | Intramembrane: {"description":"Pore-forming","evidences":[{"source":"PubMed","id":"26680202","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"27580036","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI8 |
| Number of Residues | 20 |
| Details | Transmembrane: {"description":"Helical; Name=S6 of repeat I","evidences":[{"source":"PubMed","id":"27580036","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI9 |
| Number of Residues | 18 |
| Details | Transmembrane: {"description":"Helical; Name=S1 of repeat II","evidences":[{"source":"PubMed","id":"27580036","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI10 |
| Number of Residues | 20 |
| Details | Transmembrane: {"description":"Helical; Name=S2 of repeat II","evidences":[{"source":"PubMed","id":"27580036","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI11 |
| Number of Residues | 19 |
| Details | Transmembrane: {"description":"Helical; Name=S3 of repeat II","evidences":[{"source":"PubMed","id":"27580036","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI12 |
| Number of Residues | 18 |
| Details | Transmembrane: {"description":"Helical; Name=S4 of repeat II","evidences":[{"source":"PubMed","id":"27580036","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI13 |
| Number of Residues | 19 |
| Details | Transmembrane: {"description":"Helical; Name=S5 of repeat II","evidences":[{"source":"PubMed","id":"27580036","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI14 |
| Number of Residues | 19 |
| Details | Transmembrane: {"description":"Helical; Name=S6 of repeat II","evidences":[{"source":"PubMed","id":"27580036","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI15 |
| Number of Residues | 18 |
| Details | Transmembrane: {"description":"Helical; Name=S1 of repeat III","evidences":[{"source":"PubMed","id":"27580036","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI16 |
| Number of Residues | 19 |
| Details | Transmembrane: {"description":"Helical; Name=S2 of repeat III","evidences":[{"source":"PubMed","id":"27580036","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI17 |
| Number of Residues | 18 |
| Details | Transmembrane: {"description":"Helical; Name=S3 of repeat III","evidences":[{"source":"PubMed","id":"27580036","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI18 |
| Number of Residues | 18 |
| Details | Transmembrane: {"description":"Helical; Name=S4 of repeat III","evidences":[{"source":"PubMed","id":"27580036","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI19 |
| Number of Residues | 19 |
| Details | Transmembrane: {"description":"Helical; Name=S5 of repeat III","evidences":[{"source":"PubMed","id":"27580036","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI20 |
| Number of Residues | 21 |
| Details | Transmembrane: {"description":"Helical; Name=S6 of repeat III","evidences":[{"source":"PubMed","id":"27580036","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI21 |
| Number of Residues | 21 |
| Details | Transmembrane: {"description":"Helical; Name=S1 of repeat IV","evidences":[{"source":"PubMed","id":"27580036","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI22 |
| Number of Residues | 21 |
| Details | Transmembrane: {"description":"Helical; Name=S2 of repeat IV","evidences":[{"source":"PubMed","id":"27580036","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI23 |
| Number of Residues | 19 |
| Details | Transmembrane: {"description":"Helical; Name=S3 of repeat IV","evidences":[{"source":"PubMed","id":"27580036","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI24 |
| Number of Residues | 18 |
| Details | Transmembrane: {"description":"Helical; Name=S4 of repeat IV","evidences":[{"source":"PubMed","id":"27580036","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI25 |
| Number of Residues | 20 |
| Details | Transmembrane: {"description":"Helical; Name=S5 of repeat IV","evidences":[{"source":"PubMed","id":"27580036","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI26 |
| Number of Residues | 24 |
| Details | Transmembrane: {"description":"Helical; Name=S6 of repeat IV","evidences":[{"source":"PubMed","id":"27580036","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI27 |
| Number of Residues | 246 |
| Details | Repeat: {"description":"II","evidences":[{"evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI28 |
| Number of Residues | 17 |
| Details | Region: {"description":"Binding to the beta subunit","evidences":[{"source":"PubMed","id":"27580036","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI29 |
| Number of Residues | 89 |
| Details | Region: {"description":"Dihydropyridine binding","evidences":[{"source":"PubMed","id":"1656465","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"1660150","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI30 |
| Number of Residues | 3 |
| Details | Motif: {"description":"Selectivity filter of repeat I","evidences":[{"source":"PubMed","id":"26680202","evidenceCode":"ECO:0000305"},{"source":"PubMed","id":"27580036","evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI31 |
| Number of Residues | 3 |
| Details | Motif: {"description":"Selectivity filter of repeat II","evidences":[{"source":"PubMed","id":"26680202","evidenceCode":"ECO:0000305"},{"source":"PubMed","id":"27580036","evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI32 |
| Number of Residues | 3 |
| Details | Motif: {"description":"Selectivity filter of repeat III","evidences":[{"source":"PubMed","id":"26680202","evidenceCode":"ECO:0000305"},{"source":"PubMed","id":"27580036","evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI33 |
| Number of Residues | 3 |
| Details | Motif: {"description":"Selectivity filter of repeat IV","evidences":[{"source":"PubMed","id":"26680202","evidenceCode":"ECO:0000305"},{"source":"PubMed","id":"27580036","evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI34 |
| Number of Residues | 3 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"27580036","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"5GJV","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI35 |
| Number of Residues | 1 |
| Details | Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI36 |
| Number of Residues | 1 |
| Details | Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"source":"PDB","id":"5GJV","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
