6BYH

Ubiquitin Variant (UbV.Fl11.1) bound to a human Skp1-Fbl11 fragment complex.

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000082	biological_process	G1/S transition of mitotic cell cycle
A	0000151	cellular_component	ubiquitin ligase complex
A	0000209	biological_process	protein polyubiquitination
A	0000785	cellular_component	chromatin
A	0005515	molecular_function	protein binding
A	0005634	cellular_component	nucleus
A	0005654	cellular_component	nucleoplasm
A	0005737	cellular_component	cytoplasm
A	0005813	cellular_component	centrosome
A	0005829	cellular_component	cytosol
A	0006338	biological_process	chromatin remodeling
A	0006355	biological_process	regulation of DNA-templated transcription
A	0006511	biological_process	ubiquitin-dependent protein catabolic process
A	0006879	biological_process	intracellular iron ion homeostasis
A	0007346	biological_process	regulation of mitotic cell cycle
A	0008013	molecular_function	beta-catenin binding
A	0010564	biological_process	regulation of cell cycle process
A	0010824	biological_process	regulation of centrosome duplication
A	0014033	biological_process	neural crest cell differentiation
A	0016567	biological_process	protein ubiquitination
A	0019005	cellular_component	SCF ubiquitin ligase complex
A	0019904	molecular_function	protein domain specific binding
A	0030510	biological_process	regulation of BMP signaling pathway
A	0031146	biological_process	SCF-dependent proteasomal ubiquitin-dependent protein catabolic process
A	0031467	cellular_component	Cul7-RING ubiquitin ligase complex
A	0031507	biological_process	heterochromatin formation
A	0031519	cellular_component	PcG protein complex
A	0032006	biological_process	regulation of TOR signaling
A	0035102	cellular_component	PRC1 complex
A	0042752	biological_process	regulation of circadian rhythm
A	0042981	biological_process	regulation of apoptotic process
A	0043161	biological_process	proteasome-mediated ubiquitin-dependent protein catabolic process
A	0045892	biological_process	negative regulation of DNA-templated transcription
A	0050727	biological_process	regulation of inflammatory response
A	0051124	biological_process	synaptic assembly at neuromuscular junction
A	0051298	biological_process	centrosome duplication
A	0051457	biological_process	maintenance of protein location in nucleus
A	0051726	biological_process	regulation of cell cycle
A	0060173	biological_process	limb development
A	0060271	biological_process	cilium assembly
A	0070936	biological_process	protein K48-linked ubiquitination
A	0097602	molecular_function	cullin family protein binding
A	0140677	molecular_function	molecular function activator activity
A	0160072	molecular_function	ubiquitin ligase complex scaffold activity
A	1901524	biological_process	regulation of mitophagy
A	1904415	biological_process	regulation of xenophagy
A	1990444	molecular_function	F-box domain binding
A	1990756	molecular_function	ubiquitin-like ligase-substrate adaptor activity
A	1990757	molecular_function	ubiquitin ligase activator activity
A	2000001	biological_process	regulation of DNA damage checkpoint
B	0000082	biological_process	G1/S transition of mitotic cell cycle
B	0000151	cellular_component	ubiquitin ligase complex
B	0000209	biological_process	protein polyubiquitination
B	0000785	cellular_component	chromatin
B	0005515	molecular_function	protein binding
B	0005634	cellular_component	nucleus
B	0005654	cellular_component	nucleoplasm
B	0005737	cellular_component	cytoplasm
B	0005813	cellular_component	centrosome
B	0005829	cellular_component	cytosol
B	0006338	biological_process	chromatin remodeling
B	0006355	biological_process	regulation of DNA-templated transcription
B	0006511	biological_process	ubiquitin-dependent protein catabolic process
B	0006879	biological_process	intracellular iron ion homeostasis
B	0007346	biological_process	regulation of mitotic cell cycle
B	0008013	molecular_function	beta-catenin binding
B	0010564	biological_process	regulation of cell cycle process
B	0010824	biological_process	regulation of centrosome duplication
B	0014033	biological_process	neural crest cell differentiation
B	0016567	biological_process	protein ubiquitination
B	0019005	cellular_component	SCF ubiquitin ligase complex
B	0019904	molecular_function	protein domain specific binding
B	0030510	biological_process	regulation of BMP signaling pathway
B	0031146	biological_process	SCF-dependent proteasomal ubiquitin-dependent protein catabolic process
B	0031467	cellular_component	Cul7-RING ubiquitin ligase complex
B	0031507	biological_process	heterochromatin formation
B	0031519	cellular_component	PcG protein complex
B	0032006	biological_process	regulation of TOR signaling
B	0035102	cellular_component	PRC1 complex
B	0042752	biological_process	regulation of circadian rhythm
B	0042981	biological_process	regulation of apoptotic process
B	0043161	biological_process	proteasome-mediated ubiquitin-dependent protein catabolic process
B	0045892	biological_process	negative regulation of DNA-templated transcription
B	0050727	biological_process	regulation of inflammatory response
B	0051124	biological_process	synaptic assembly at neuromuscular junction
B	0051298	biological_process	centrosome duplication
B	0051457	biological_process	maintenance of protein location in nucleus
B	0051726	biological_process	regulation of cell cycle
B	0060173	biological_process	limb development
B	0060271	biological_process	cilium assembly
B	0070936	biological_process	protein K48-linked ubiquitination
B	0097602	molecular_function	cullin family protein binding
B	0140677	molecular_function	molecular function activator activity
B	0160072	molecular_function	ubiquitin ligase complex scaffold activity
B	1901524	biological_process	regulation of mitophagy
B	1904415	biological_process	regulation of xenophagy
B	1990444	molecular_function	F-box domain binding
B	1990756	molecular_function	ubiquitin-like ligase-substrate adaptor activity
B	1990757	molecular_function	ubiquitin ligase activator activity
B	2000001	biological_process	regulation of DNA damage checkpoint
G	0000082	biological_process	G1/S transition of mitotic cell cycle
G	0000151	cellular_component	ubiquitin ligase complex
G	0000209	biological_process	protein polyubiquitination
G	0000785	cellular_component	chromatin
G	0005515	molecular_function	protein binding
G	0005634	cellular_component	nucleus
G	0005654	cellular_component	nucleoplasm
G	0005737	cellular_component	cytoplasm
G	0005813	cellular_component	centrosome
G	0005829	cellular_component	cytosol
G	0006338	biological_process	chromatin remodeling
G	0006355	biological_process	regulation of DNA-templated transcription
G	0006511	biological_process	ubiquitin-dependent protein catabolic process
G	0006879	biological_process	intracellular iron ion homeostasis
G	0007346	biological_process	regulation of mitotic cell cycle
G	0008013	molecular_function	beta-catenin binding
G	0010564	biological_process	regulation of cell cycle process
G	0010824	biological_process	regulation of centrosome duplication
G	0014033	biological_process	neural crest cell differentiation
G	0016567	biological_process	protein ubiquitination
G	0019005	cellular_component	SCF ubiquitin ligase complex
G	0019904	molecular_function	protein domain specific binding
G	0030510	biological_process	regulation of BMP signaling pathway
G	0031146	biological_process	SCF-dependent proteasomal ubiquitin-dependent protein catabolic process
G	0031467	cellular_component	Cul7-RING ubiquitin ligase complex
G	0031507	biological_process	heterochromatin formation
G	0031519	cellular_component	PcG protein complex
G	0032006	biological_process	regulation of TOR signaling
G	0035102	cellular_component	PRC1 complex
G	0042752	biological_process	regulation of circadian rhythm
G	0042981	biological_process	regulation of apoptotic process
G	0043161	biological_process	proteasome-mediated ubiquitin-dependent protein catabolic process
G	0045892	biological_process	negative regulation of DNA-templated transcription
G	0050727	biological_process	regulation of inflammatory response
G	0051124	biological_process	synaptic assembly at neuromuscular junction
G	0051298	biological_process	centrosome duplication
G	0051457	biological_process	maintenance of protein location in nucleus
G	0051726	biological_process	regulation of cell cycle
G	0060173	biological_process	limb development
G	0060271	biological_process	cilium assembly
G	0070936	biological_process	protein K48-linked ubiquitination
G	0097602	molecular_function	cullin family protein binding
G	0140677	molecular_function	molecular function activator activity
G	0160072	molecular_function	ubiquitin ligase complex scaffold activity
G	1901524	biological_process	regulation of mitophagy
G	1904415	biological_process	regulation of xenophagy
G	1990444	molecular_function	F-box domain binding
G	1990756	molecular_function	ubiquitin-like ligase-substrate adaptor activity
G	1990757	molecular_function	ubiquitin ligase activator activity
G	2000001	biological_process	regulation of DNA damage checkpoint

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	3
Details	Modified residue: {"description":"Phosphothreonine","evidences":[{"source":"PubMed","id":"20068231","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"21406692","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI2
Number of Residues	6
Details	Cross-link: {"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO1)","evidences":[{"source":"PubMed","id":"25114211","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

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