6BUV

Structure of Mycobacterium tuberculosis NadD in complex with inhibitor [(1~{R},2~{R},5~{S})-5-methyl-2-propan-2-yl-cyclohexyl] 2-[3-methyl-2-(phenoxymethyl)benzimidazol-1-yl]ethanoate

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000166	molecular_function	nucleotide binding
A	0000309	molecular_function	nicotinamide-nucleotide adenylyltransferase activity
A	0003824	molecular_function	catalytic activity
A	0004515	molecular_function	nicotinate-nucleotide adenylyltransferase activity
A	0005524	molecular_function	ATP binding
A	0009058	biological_process	biosynthetic process
A	0009435	biological_process	NAD+ biosynthetic process
A	0016740	molecular_function	transferase activity
A	0016779	molecular_function	nucleotidyltransferase activity
A	0019363	biological_process	pyridine nucleotide biosynthetic process
A	0034355	biological_process	NAD+ biosynthetic process via the salvage pathway
A	0070566	molecular_function	adenylyltransferase activity
B	0000166	molecular_function	nucleotide binding
B	0000309	molecular_function	nicotinamide-nucleotide adenylyltransferase activity
B	0003824	molecular_function	catalytic activity
B	0004515	molecular_function	nicotinate-nucleotide adenylyltransferase activity
B	0005524	molecular_function	ATP binding
B	0009058	biological_process	biosynthetic process
B	0009435	biological_process	NAD+ biosynthetic process
B	0016740	molecular_function	transferase activity
B	0016779	molecular_function	nucleotidyltransferase activity
B	0019363	biological_process	pyridine nucleotide biosynthetic process
B	0034355	biological_process	NAD+ biosynthetic process via the salvage pathway
B	0070566	molecular_function	adenylyltransferase activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	7
Details	binding site for residue NA A 301

Chain	Residue
A	ARG128
A	ASP154
A	LEU156
A	THR157
A	HOH426
B	SER116
B	TRP117

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site_id	AC2
Number of Residues	2
Details	binding site for residue CL A 302

Chain	Residue
A	VAL73
A	ARG196

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site_id	AC3
Number of Residues	4
Details	binding site for residue CL A 303

Chain	Residue
A	HIS97
A	PRO98
A	ASP99
A	SER100

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site_id	AC4
Number of Residues	3
Details	binding site for residue CL A 304

Chain	Residue
A	TYR85
A	GLY119
A	HOH483

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site_id	AC5
Number of Residues	8
Details	binding site for residue E9A B 301

Chain	Residue
A	LEU158
A	GLU160
B	ALA108
B	ASP109
B	ALA112
B	SER113
B	SER116
B	ILE144

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site_id	AC6
Number of Residues	2
Details	binding site for residue CL B 302

Chain	Residue
B	VAL73
B	ARG196

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site_id	AC7
Number of Residues	6
Details	binding site for residue CL B 303

Chain	Residue
B	HIS17
B	HIS20
B	ARG134
B	SER167
B	SER168
B	HOH482

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