Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

6BMI

Crystal Structure of GltPh R397C in complex with L-Serine

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005283	molecular_function	amino acid:sodium symporter activity
A	0005886	cellular_component	plasma membrane
A	0006835	biological_process	dicarboxylic acid transport
A	0006865	biological_process	amino acid transport
A	0015108	molecular_function	chloride transmembrane transporter activity
A	0015183	molecular_function	L-aspartate transmembrane transporter activity
A	0015293	molecular_function	symporter activity
A	0015501	molecular_function	glutamate:sodium symporter activity
A	0016020	cellular_component	membrane
A	0035725	biological_process	sodium ion transmembrane transport
A	0042802	molecular_function	identical protein binding
A	0046872	molecular_function	metal ion binding
A	0070207	biological_process	protein homotrimerization
A	0070778	biological_process	L-aspartate transmembrane transport
A	0140009	biological_process	L-aspartate import across plasma membrane
A	1902476	biological_process	chloride transmembrane transport
B	0005283	molecular_function	amino acid:sodium symporter activity
B	0005886	cellular_component	plasma membrane
B	0006835	biological_process	dicarboxylic acid transport
B	0006865	biological_process	amino acid transport
B	0015108	molecular_function	chloride transmembrane transporter activity
B	0015183	molecular_function	L-aspartate transmembrane transporter activity
B	0015293	molecular_function	symporter activity
B	0015501	molecular_function	glutamate:sodium symporter activity
B	0016020	cellular_component	membrane
B	0035725	biological_process	sodium ion transmembrane transport
B	0042802	molecular_function	identical protein binding
B	0046872	molecular_function	metal ion binding
B	0070207	biological_process	protein homotrimerization
B	0070778	biological_process	L-aspartate transmembrane transport
B	0140009	biological_process	L-aspartate import across plasma membrane
B	1902476	biological_process	chloride transmembrane transport
C	0005283	molecular_function	amino acid:sodium symporter activity
C	0005886	cellular_component	plasma membrane
C	0006835	biological_process	dicarboxylic acid transport
C	0006865	biological_process	amino acid transport
C	0015108	molecular_function	chloride transmembrane transporter activity
C	0015183	molecular_function	L-aspartate transmembrane transporter activity
C	0015293	molecular_function	symporter activity
C	0015501	molecular_function	glutamate:sodium symporter activity
C	0016020	cellular_component	membrane
C	0035725	biological_process	sodium ion transmembrane transport
C	0042802	molecular_function	identical protein binding
C	0046872	molecular_function	metal ion binding
C	0070207	biological_process	protein homotrimerization
C	0070778	biological_process	L-aspartate transmembrane transport
C	0140009	biological_process	L-aspartate import across plasma membrane
C	1902476	biological_process	chloride transmembrane transport

Functional Information from PDB Data

site_id	AC1
Number of Residues	5
Details	binding site for residue NA A 501

Chain	Residue
A	GLY306
A	ALA307
A	ASN310
A	ASN401
A	ASP405

site_id	AC2
Number of Residues	6
Details	binding site for residue SER A 502

Chain	Residue
A	THR398
A	ASN401
A	ARG276
A	SER278
A	THR314
A	ASP394

site_id	AC3
Number of Residues	5
Details	binding site for residue NA B 501

Chain	Residue
B	GLY306
B	ALA307
B	ASN310
B	ASN401
B	ASP405

site_id	AC4
Number of Residues	6
Details	binding site for residue SER B 502

Chain	Residue
B	ARG276
B	SER278
B	THR314
B	ASP394
B	THR398
B	ASN401

site_id	AC5
Number of Residues	6
Details	binding site for residue NA C 501

Chain	Residue
C	SER278
C	GLY306
C	ALA307
C	ASN310
C	ASN401
C	ASP405

site_id	AC6
Number of Residues	4
Details	binding site for residue NA C 502

Chain	Residue
C	THR308
C	SER349
C	ILE350
C	THR352

site_id	AC7
Number of Residues	6
Details	binding site for residue SER C 503

Chain	Residue
C	ARG276
C	SER278
C	THR314
C	ASP394
C	THR398
C	ASN401

Functional Information from PROSITE/UniProt

site_id	PS00713
Number of Residues	16
Details	NA_DICARBOXYL_SYMP_1 Sodium:dicarboxylate symporter family signature 1. PfGDlFVrLLKMLVmP

Chain	Residue	Details
A	PRO45-PRO60

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	54
Details	Transmembrane: {"description":"Helical; Name=1","evidences":[{"source":"PubMed","id":"15483603","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

site_id	SWS_FT_FI2
Number of Residues	216
Details	Topological domain: {"description":"Extracellular","evidences":[{"source":"PubMed","id":"15483603","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

site_id	SWS_FT_FI3
Number of Residues	60
Details	Transmembrane: {"description":"Helical; Name=2","evidences":[{"source":"PubMed","id":"15483603","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

site_id	SWS_FT_FI4
Number of Residues	201
Details	Topological domain: {"description":"Cytoplasmic","evidences":[{"source":"PubMed","id":"15483603","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

site_id	SWS_FT_FI5
Number of Residues	66
Details	Transmembrane: {"description":"Helical; Name=3","evidences":[{"source":"PubMed","id":"15483603","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

site_id	SWS_FT_FI6
Number of Residues	114
Details	Transmembrane: {"description":"Discontinuously helical; Name=4","evidences":[{"source":"PubMed","id":"15483603","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

site_id	SWS_FT_FI7
Number of Residues	63
Details	Transmembrane: {"description":"Helical; Name=5","evidences":[{"source":"PubMed","id":"15483603","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

site_id	SWS_FT_FI8
Number of Residues	60
Details	Transmembrane: {"description":"Helical; Name=6","evidences":[{"source":"PubMed","id":"15483603","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

site_id	SWS_FT_FI9
Number of Residues	118
Details	Intramembrane: {"description":"Discontinuously helical","evidences":[{"source":"PubMed","id":"15483603","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

site_id	SWS_FT_FI10
Number of Residues	66
Details	Transmembrane: {"description":"Discontinuously helical; Name=7","evidences":[{"source":"PubMed","id":"15483603","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

site_id	SWS_FT_FI11
Number of Residues	60
Details	Transmembrane: {"description":"Helical; Name=8","evidences":[{"source":"PubMed","id":"15483603","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

site_id	SWS_FT_FI12
Number of Residues	13
Details	Binding site: {"evidences":[{"source":"PubMed","id":"17230192","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"2NWL","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2NWX","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3KBC","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

site_id	SWS_FT_FI13
Number of Residues	13
Details	Binding site: {"evidences":[{"source":"PubMed","id":"17230192","evidenceCode":"ECO:0000305"},{"source":"PDB","id":"2NWX","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

site_id	SWS_FT_FI14
Number of Residues	3
Details	Binding site: {"evidences":[{"source":"PubMed","id":"17230192","evidenceCode":"ECO:0000305"},{"source":"PDB","id":"2NWX","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4X2S","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		PDB format (full)
		Validation report (PDF)
		EDMap 2fo-fc (MTZ)