6BJD

Crystal Structure of Human Calpain-3 Protease Core in Complex with E-64

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004198	molecular_function	calcium-dependent cysteine-type endopeptidase activity
A	0006508	biological_process	proteolysis
B	0004198	molecular_function	calcium-dependent cysteine-type endopeptidase activity
B	0006508	biological_process	proteolysis
C	0004198	molecular_function	calcium-dependent cysteine-type endopeptidase activity
C	0006508	biological_process	proteolysis
D	0004198	molecular_function	calcium-dependent cysteine-type endopeptidase activity
D	0006508	biological_process	proteolysis

Functional Information from PROSITE/UniProt

site_id	PS00139
Number of Residues	12
Details	THIOL_PROTEASE_CYS Eukaryotic thiol (cysteine) proteases cysteine active site. QGeLGDCWFlAA

Chain	Residue	Details
A	GLN123-ALA134

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	12
Details	ACT_SITE: ACT_SITE => ECO:0000255|PROSITE-ProRule:PRU00239

Chain	Residue	Details
A	CYS129
A	HIS334
A	ASN358
B	CYS129
B	HIS334
B	ASN358
C	CYS129
C	HIS334
C	ASN358
D	CYS129
D	HIS334
D	ASN358

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