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6BJD

Crystal Structure of Human Calpain-3 Protease Core in Complex with E-64

Functional Information from GO Data
ChainGOidnamespacecontents
A0004198molecular_functioncalcium-dependent cysteine-type endopeptidase activity
A0006508biological_processproteolysis
B0004198molecular_functioncalcium-dependent cysteine-type endopeptidase activity
B0006508biological_processproteolysis
C0004198molecular_functioncalcium-dependent cysteine-type endopeptidase activity
C0006508biological_processproteolysis
D0004198molecular_functioncalcium-dependent cysteine-type endopeptidase activity
D0006508biological_processproteolysis
Functional Information from PROSITE/UniProt
site_idPS00139
Number of Residues12
DetailsTHIOL_PROTEASE_CYS Eukaryotic thiol (cysteine) proteases cysteine active site. QGeLGDCWFlAA
ChainResidueDetails
AGLN123-ALA134

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues12
DetailsActive site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU00239","evidenceCode":"ECO:0000255"}]}
ChainResidueDetails

247947

PDB entries from 2026-01-21

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