6BCM
Structure of a Self-inhibited N475A variant of the Venezuelan Equine Encephalitis Virus (VEEV) nsP2 cysteine protease
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 5 |
| Details | binding site for residue GOL A 801 |
| Chain | Residue |
| A | ASN544 |
| A | HIS546 |
| A | LEU610 |
| A | GOL802 |
| A | HOH921 |
| site_id | AC2 |
| Number of Residues | 7 |
| Details | binding site for residue GOL A 802 |
| Chain | Residue |
| A | GOL801 |
| A | HOH906 |
| A | HOH954 |
| A | ARG543 |
| A | ARG604 |
| A | ARG605 |
| A | LEU606 |
| site_id | AC3 |
| Number of Residues | 5 |
| Details | binding site for residue NA A 803 |
| Chain | Residue |
| A | GLN739 |
| A | ASP765 |
| A | ARG766 |
| A | LYS767 |
| A | HOH1007 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | ACT_SITE: For cysteine protease nsP2 activity => ECO:0000255|PROSITE-ProRule:PRU00853, ECO:0000269|PubMed:16962975 |
| Chain | Residue | Details |
| A | PRO466 | |
| A | ALA535 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 1 |
| Details | SITE: Cleavage; by protease nsP2 => ECO:0000250|UniProtKB:P03317 |
| Chain | Residue | Details |
| A | ILE783 |
