6BCM
Structure of a Self-inhibited N475A variant of the Venezuelan Equine Encephalitis Virus (VEEV) nsP2 cysteine protease
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 5 |
| Details | binding site for residue GOL A 801 |
| Chain | Residue |
| A | ASN544 |
| A | HIS546 |
| A | LEU610 |
| A | GOL802 |
| A | HOH921 |
| site_id | AC2 |
| Number of Residues | 7 |
| Details | binding site for residue GOL A 802 |
| Chain | Residue |
| A | GOL801 |
| A | HOH906 |
| A | HOH954 |
| A | ARG543 |
| A | ARG604 |
| A | ARG605 |
| A | LEU606 |
| site_id | AC3 |
| Number of Residues | 5 |
| Details | binding site for residue NA A 803 |
| Chain | Residue |
| A | GLN739 |
| A | ASP765 |
| A | ARG766 |
| A | LYS767 |
| A | HOH1007 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 9 |
| Details | Motif: {"description":"Nuclear export signal","evidences":[{"source":"PubMed","id":"17652399","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 4 |
| Details | Motif: {"description":"Nuclear localization signal","evidences":[{"source":"PubMed","id":"17652399","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 2 |
| Details | Active site: {"description":"For cysteine protease nsP2 activity","evidences":[{"source":"PROSITE-ProRule","id":"PRU00853","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"16962975","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
