6BC7

Cryo X-ray structure of sisomicin bound AAC-VIa

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0016746	molecular_function	acyltransferase activity
A	0046353	molecular_function	aminoglycoside 3-N-acetyltransferase activity
A	0046677	biological_process	response to antibiotic
A	0046872	molecular_function	metal ion binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	17
Details	binding site for residue SIS A 301

Chain	Residue
A	SER79
A	ASN226
A	ASP239
A	ACT302
A	HOH421
A	HOH424
A	HOH498
A	HOH520
A	HOH543
A	TYR85
A	TYR113
A	PHE116
A	ASP136
A	TYR159
A	ASP183
A	HIS189
A	SER225

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site_id	AC2
Number of Residues	4
Details	binding site for residue ACT A 302

Chain	Residue
A	ALA184
A	THR186
A	SIS301
A	HOH578

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