Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

6BAQ

Mus musculus BPIFA1

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005576	cellular_component	extracellular region
A	0005615	cellular_component	extracellular space
A	0005902	cellular_component	microvillus
A	0008289	molecular_function	lipid binding
A	0019731	biological_process	antibacterial humoral response
A	0042742	biological_process	defense response to bacterium
A	0043129	biological_process	surfactant homeostasis
A	0045087	biological_process	innate immune response
A	0050891	biological_process	multicellular organismal-level water homeostasis
A	1900229	biological_process	negative regulation of single-species biofilm formation in or on host organism
A	1902305	biological_process	regulation of sodium ion transmembrane transport
B	0005576	cellular_component	extracellular region
B	0005615	cellular_component	extracellular space
B	0005902	cellular_component	microvillus
B	0008289	molecular_function	lipid binding
B	0019731	biological_process	antibacterial humoral response
B	0042742	biological_process	defense response to bacterium
B	0043129	biological_process	surfactant homeostasis
B	0045087	biological_process	innate immune response
B	0050891	biological_process	multicellular organismal-level water homeostasis
B	1900229	biological_process	negative regulation of single-species biofilm formation in or on host organism
B	1902305	biological_process	regulation of sodium ion transmembrane transport
C	0005576	cellular_component	extracellular region
C	0005615	cellular_component	extracellular space
C	0005902	cellular_component	microvillus
C	0008289	molecular_function	lipid binding
C	0019731	biological_process	antibacterial humoral response
C	0042742	biological_process	defense response to bacterium
C	0043129	biological_process	surfactant homeostasis
C	0045087	biological_process	innate immune response
C	0050891	biological_process	multicellular organismal-level water homeostasis
C	1900229	biological_process	negative regulation of single-species biofilm formation in or on host organism
C	1902305	biological_process	regulation of sodium ion transmembrane transport
D	0005576	cellular_component	extracellular region
D	0005615	cellular_component	extracellular space
D	0005902	cellular_component	microvillus
D	0008289	molecular_function	lipid binding
D	0019731	biological_process	antibacterial humoral response
D	0042742	biological_process	defense response to bacterium
D	0043129	biological_process	surfactant homeostasis
D	0045087	biological_process	innate immune response
D	0050891	biological_process	multicellular organismal-level water homeostasis
D	1900229	biological_process	negative regulation of single-species biofilm formation in or on host organism
D	1902305	biological_process	regulation of sodium ion transmembrane transport
E	0005576	cellular_component	extracellular region
E	0005615	cellular_component	extracellular space
E	0005902	cellular_component	microvillus
E	0008289	molecular_function	lipid binding
E	0019731	biological_process	antibacterial humoral response
E	0042742	biological_process	defense response to bacterium
E	0043129	biological_process	surfactant homeostasis
E	0045087	biological_process	innate immune response
E	0050891	biological_process	multicellular organismal-level water homeostasis
E	1900229	biological_process	negative regulation of single-species biofilm formation in or on host organism
E	1902305	biological_process	regulation of sodium ion transmembrane transport
F	0005576	cellular_component	extracellular region
F	0005615	cellular_component	extracellular space
F	0005902	cellular_component	microvillus
F	0008289	molecular_function	lipid binding
F	0019731	biological_process	antibacterial humoral response
F	0042742	biological_process	defense response to bacterium
F	0043129	biological_process	surfactant homeostasis
F	0045087	biological_process	innate immune response
F	0050891	biological_process	multicellular organismal-level water homeostasis
F	1900229	biological_process	negative regulation of single-species biofilm formation in or on host organism
F	1902305	biological_process	regulation of sodium ion transmembrane transport
G	0005576	cellular_component	extracellular region
G	0005615	cellular_component	extracellular space
G	0005902	cellular_component	microvillus
G	0008289	molecular_function	lipid binding
G	0019731	biological_process	antibacterial humoral response
G	0042742	biological_process	defense response to bacterium
G	0043129	biological_process	surfactant homeostasis
G	0045087	biological_process	innate immune response
G	0050891	biological_process	multicellular organismal-level water homeostasis
G	1900229	biological_process	negative regulation of single-species biofilm formation in or on host organism
G	1902305	biological_process	regulation of sodium ion transmembrane transport
H	0005576	cellular_component	extracellular region
H	0005615	cellular_component	extracellular space
H	0005902	cellular_component	microvillus
H	0008289	molecular_function	lipid binding
H	0019731	biological_process	antibacterial humoral response
H	0042742	biological_process	defense response to bacterium
H	0043129	biological_process	surfactant homeostasis
H	0045087	biological_process	innate immune response
H	0050891	biological_process	multicellular organismal-level water homeostasis
H	1900229	biological_process	negative regulation of single-species biofilm formation in or on host organism
H	1902305	biological_process	regulation of sodium ion transmembrane transport

Functional Information from PDB Data

site_id	AC1
Number of Residues	4
Details	binding site for residue NA A 301

Chain	Residue
A	THR205
A	HIS206
B	THR205
B	HIS206

site_id	AC2
Number of Residues	3
Details	binding site for residue NA A 302

Chain	Residue
A	THR69
A	ASP70
A	PHE274

site_id	AC3
Number of Residues	3
Details	binding site for residue NA A 303

Chain	Residue
E	GLY91
A	ASP78
E	LEU90

site_id	AC4
Number of Residues	4
Details	binding site for residue NA A 304

Chain	Residue
A	ASN129
A	MET168
A	PRO169
A	VAL170

site_id	AC5
Number of Residues	1
Details	binding site for residue NA A 305

Chain	Residue
A	SER210

site_id	AC6
Number of Residues	3
Details	binding site for residue NA A 306

Chain	Residue
A	PRO65
A	SER66
A	PRO68

site_id	AC7
Number of Residues	3
Details	binding site for residue NA A 307

Chain	Residue
A	LEU174
A	GLN176
A	LEU216

site_id	AC8
Number of Residues	1
Details	binding site for residue NA A 308

Chain	Residue
A	ILE135

site_id	AC9
Number of Residues	3
Details	binding site for residue NA A 309

Chain	Residue
A	PRO149
A	ASP150
A	ARG153

site_id	AD1
Number of Residues	6
Details	binding site for residue NA A 310

Chain	Residue
A	THR69
A	ASP70
A	LEU72
A	ALA73
A	PHE274
A	HOH424

site_id	AD2
Number of Residues	3
Details	binding site for residue NA A 311

Chain	Residue
A	ASP137
E	GLU142
E	HOH417

site_id	AD3
Number of Residues	4
Details	binding site for residue NA B 301

Chain	Residue
B	ILE92
B	ASN95
B	ILE96
B	LYS244

site_id	AD4
Number of Residues	1
Details	binding site for residue NA B 302

Chain	Residue
B	GLY87

site_id	AD5
Number of Residues	4
Details	binding site for residue NA B 303

Chain	Residue
B	PRO149
B	GLN273
F	HIS262
F	NA304

site_id	AD6
Number of Residues	3
Details	binding site for residue NA B 304

Chain	Residue
B	GLY144
B	TYR155
B	THR157

site_id	AD7
Number of Residues	6
Details	binding site for residue NA B 305

Chain	Residue
B	PRO149
B	ASP150
B	GLY151
B	GLY271
B	GLN273
F	HIS262

site_id	AD8
Number of Residues	2
Details	binding site for residue NA B 306

Chain	Residue
B	HIS152
B	ALA189

site_id	AD9
Number of Residues	5
Details	binding site for residue CL B 307

Chain	Residue
B	ASP70
B	LEU71
B	LEU72
B	ALA73
B	PHE274

site_id	AE1
Number of Residues	4
Details	binding site for residue GOL C 301

Chain	Residue
C	ASP150
C	HIS152
C	HIS270
C	GLY271

site_id	AE2
Number of Residues	2
Details	binding site for residue NA C 302

Chain	Residue
C	GLN273
C	VAL275

site_id	AE3
Number of Residues	4
Details	binding site for residue NA C 303

Chain	Residue
C	THR205
C	HIS206
G	THR205
G	HIS206

site_id	AE4
Number of Residues	1
Details	binding site for residue NA C 304

Chain	Residue
C	GLY87

site_id	AE5
Number of Residues	4
Details	binding site for residue NA C 305

Chain	Residue
C	LEU85
C	GLY88
C	LEU89
C	LEU90

site_id	AE6
Number of Residues	4
Details	binding site for residue NA C 306

Chain	Residue
C	VAL200
C	LEU201
C	ASN250
F	SER123

site_id	AE7
Number of Residues	3
Details	binding site for residue NA C 307

Chain	Residue
C	SER81
C	GLU142
C	LEU143

site_id	AE8
Number of Residues	4
Details	binding site for residue NA C 308

Chain	Residue
C	PRO125
C	LEU126
C	ASN128
C	ASN129

site_id	AE9
Number of Residues	3
Details	binding site for residue NA C 309

Chain	Residue
C	VAL258
H	LYS103
H	NA307

site_id	AF1
Number of Residues	1
Details	binding site for residue NA D 302

Chain	Residue
D	ASN263

site_id	AF2
Number of Residues	2
Details	binding site for residue NA D 303

Chain	Residue
D	GLN176
D	LEU216

site_id	AF3
Number of Residues	4
Details	binding site for residue NA D 304

Chain	Residue
D	ASP203
F	GLY209
F	SER210
F	LEU211

site_id	AF4
Number of Residues	4
Details	binding site for residue NA E 301

Chain	Residue
E	THR205
E	HIS206
H	THR205
H	HIS206

site_id	AF5
Number of Residues	4
Details	binding site for residue NA E 302

Chain	Residue
E	THR234
E	LYS235
E	GLU239
H	ASP203

site_id	AF6
Number of Residues	2
Details	binding site for residue NA E 303

Chain	Residue
E	ILE96
E	ILE133

site_id	AF7
Number of Residues	3
Details	binding site for residue NA E 304

Chain	Residue
E	THR69
E	ASP70
E	PHE274

site_id	AF8
Number of Residues	2
Details	binding site for residue NA E 305

Chain	Residue
E	GLN273
E	VAL275

site_id	AF9
Number of Residues	2
Details	binding site for residue NA E 306

Chain	Residue
E	SER210
E	HOH424

site_id	AG1
Number of Residues	1
Details	binding site for residue NA E 307

Chain	Residue
E	LYS244

site_id	AG2
Number of Residues	2
Details	binding site for residue NA E 308

Chain	Residue
E	ASP137
E	THR163

site_id	AG3
Number of Residues	3
Details	binding site for residue NA E 309

Chain	Residue
E	PRO149
E	ASP150
E	ARG153

site_id	AG4
Number of Residues	3
Details	binding site for residue NA F 301

Chain	Residue
F	PRO149
F	ASP150
F	ARG153

site_id	AG5
Number of Residues	2
Details	binding site for residue NA F 302

Chain	Residue
F	PRO68
F	LEU71

site_id	AG6
Number of Residues	2
Details	binding site for residue NA F 303

Chain	Residue
F	ASN182
F	HOH447

site_id	AG7
Number of Residues	2
Details	binding site for residue NA F 304

Chain	Residue
B	NA303
F	HOH467

site_id	AG8
Number of Residues	3
Details	binding site for residue NA F 305

Chain	Residue
F	SER254
F	GLY255
F	LEU256

site_id	AG9
Number of Residues	2
Details	binding site for residue GOL G 301

Chain	Residue
G	PRO208
G	HOH432

site_id	AH1
Number of Residues	5
Details	binding site for residue NA G 302

Chain	Residue
A	GLY172
A	SER173
C	SER224
G	LYS191
G	ASP192

site_id	AH2
Number of Residues	3
Details	binding site for residue NA G 303

Chain	Residue
G	LEU90
G	GLY91
G	HOH416

site_id	AH3
Number of Residues	1
Details	binding site for residue NA G 304

Chain	Residue
G	ASN67

site_id	AH4
Number of Residues	4
Details	binding site for residue NA G 305

Chain	Residue
G	SER254
G	GLY255
G	LEU256
G	HOH430

site_id	AH5
Number of Residues	3
Details	binding site for residue NA G 306

Chain	Residue
G	THR69
G	ASP70
G	PHE274

site_id	AH6
Number of Residues	2
Details	binding site for residue NA G 307

Chain	Residue
G	GLN273
G	VAL275

site_id	AH7
Number of Residues	4
Details	binding site for residue NA G 308

Chain	Residue
C	ASP203
G	THR234
G	PRO238
G	GLU239

site_id	AH8
Number of Residues	2
Details	binding site for residue NA G 309

Chain	Residue
C	THR234
G	ASP203

site_id	AH9
Number of Residues	2
Details	binding site for residue NA G 310

Chain	Residue
G	LEU71
G	LYS75

site_id	AI1
Number of Residues	2
Details	binding site for residue NA G 311

Chain	Residue
G	GLN139
G	HOH441

site_id	AI2
Number of Residues	1
Details	binding site for residue NA G 312

Chain	Residue
G	ILE135

site_id	AI3
Number of Residues	3
Details	binding site for residue NA G 313

Chain	Residue
G	ASP257
G	THR259
H	ILE276

site_id	AI4
Number of Residues	3
Details	binding site for residue NA G 314

Chain	Residue
G	PRO149
G	ASP150
G	ARG153

site_id	AI5
Number of Residues	5
Details	binding site for residue GOL H 301

Chain	Residue
H	ASP150
H	HIS152
H	HIS270
H	HOH402
H	HOH406

site_id	AI6
Number of Residues	2
Details	binding site for residue GOL H 302

Chain	Residue
E	PRO208
H	TYR155

site_id	AI7
Number of Residues	3
Details	binding site for residue NA H 303

Chain	Residue
H	PRO149
H	ASP150
H	ARG153

site_id	AI8
Number of Residues	4
Details	binding site for residue NA H 304

Chain	Residue
H	LEU174
H	GLN176
H	LEU216
H	ASN217

site_id	AI9
Number of Residues	4
Details	binding site for residue NA H 305

Chain	Residue
G	ASN263
G	HOH428
H	GLY271
H	HOH407

site_id	AJ1
Number of Residues	5
Details	binding site for residue NA H 307

Chain	Residue
C	NA309
H	LYS103
H	LEU127
H	ASN128
H	ILE130

site_id	AJ2
Number of Residues	2
Details	binding site for residue NA H 308

Chain	Residue
H	LEU256
H	ASP257

site_id	AJ3
Number of Residues	4
Details	binding site for residue NA H 309

Chain	Residue
F	VAL170
F	VAL171
F	GLY172
H	ASN228

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	16
Details	CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000255

Chain	Residue	Details
A	ASN182
E	ASN228
F	ASN182
F	ASN228
G	ASN182
G	ASN228
H	ASN182
H	ASN228
A	ASN228
B	ASN182
B	ASN228
C	ASN182
C	ASN228
D	ASN182
D	ASN228
E	ASN182

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		PDB format (full)
		Validation report (PDF)
		EDMap 2fo-fc (MTZ)