6BAQ
Mus musculus BPIFA1
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0002376 | biological_process | immune system process |
| A | 0002395 | biological_process | immune response in nasopharyngeal-associated lymphoid tissue |
| A | 0005576 | cellular_component | extracellular region |
| A | 0005615 | cellular_component | extracellular space |
| A | 0005902 | cellular_component | microvillus |
| A | 0008289 | molecular_function | lipid binding |
| A | 0019731 | biological_process | antibacterial humoral response |
| A | 0042742 | biological_process | defense response to bacterium |
| A | 0043129 | biological_process | surfactant homeostasis |
| A | 0045087 | biological_process | innate immune response |
| A | 0050891 | biological_process | multicellular organismal-level water homeostasis |
| A | 0061844 | biological_process | antimicrobial humoral immune response mediated by antimicrobial peptide |
| A | 1900229 | biological_process | negative regulation of single-species biofilm formation in or on host organism |
| A | 1902305 | biological_process | regulation of sodium ion transmembrane transport |
| B | 0002376 | biological_process | immune system process |
| B | 0002395 | biological_process | immune response in nasopharyngeal-associated lymphoid tissue |
| B | 0005576 | cellular_component | extracellular region |
| B | 0005615 | cellular_component | extracellular space |
| B | 0005902 | cellular_component | microvillus |
| B | 0008289 | molecular_function | lipid binding |
| B | 0019731 | biological_process | antibacterial humoral response |
| B | 0042742 | biological_process | defense response to bacterium |
| B | 0043129 | biological_process | surfactant homeostasis |
| B | 0045087 | biological_process | innate immune response |
| B | 0050891 | biological_process | multicellular organismal-level water homeostasis |
| B | 0061844 | biological_process | antimicrobial humoral immune response mediated by antimicrobial peptide |
| B | 1900229 | biological_process | negative regulation of single-species biofilm formation in or on host organism |
| B | 1902305 | biological_process | regulation of sodium ion transmembrane transport |
| C | 0002376 | biological_process | immune system process |
| C | 0002395 | biological_process | immune response in nasopharyngeal-associated lymphoid tissue |
| C | 0005576 | cellular_component | extracellular region |
| C | 0005615 | cellular_component | extracellular space |
| C | 0005902 | cellular_component | microvillus |
| C | 0008289 | molecular_function | lipid binding |
| C | 0019731 | biological_process | antibacterial humoral response |
| C | 0042742 | biological_process | defense response to bacterium |
| C | 0043129 | biological_process | surfactant homeostasis |
| C | 0045087 | biological_process | innate immune response |
| C | 0050891 | biological_process | multicellular organismal-level water homeostasis |
| C | 0061844 | biological_process | antimicrobial humoral immune response mediated by antimicrobial peptide |
| C | 1900229 | biological_process | negative regulation of single-species biofilm formation in or on host organism |
| C | 1902305 | biological_process | regulation of sodium ion transmembrane transport |
| D | 0002376 | biological_process | immune system process |
| D | 0002395 | biological_process | immune response in nasopharyngeal-associated lymphoid tissue |
| D | 0005576 | cellular_component | extracellular region |
| D | 0005615 | cellular_component | extracellular space |
| D | 0005902 | cellular_component | microvillus |
| D | 0008289 | molecular_function | lipid binding |
| D | 0019731 | biological_process | antibacterial humoral response |
| D | 0042742 | biological_process | defense response to bacterium |
| D | 0043129 | biological_process | surfactant homeostasis |
| D | 0045087 | biological_process | innate immune response |
| D | 0050891 | biological_process | multicellular organismal-level water homeostasis |
| D | 0061844 | biological_process | antimicrobial humoral immune response mediated by antimicrobial peptide |
| D | 1900229 | biological_process | negative regulation of single-species biofilm formation in or on host organism |
| D | 1902305 | biological_process | regulation of sodium ion transmembrane transport |
| E | 0002376 | biological_process | immune system process |
| E | 0002395 | biological_process | immune response in nasopharyngeal-associated lymphoid tissue |
| E | 0005576 | cellular_component | extracellular region |
| E | 0005615 | cellular_component | extracellular space |
| E | 0005902 | cellular_component | microvillus |
| E | 0008289 | molecular_function | lipid binding |
| E | 0019731 | biological_process | antibacterial humoral response |
| E | 0042742 | biological_process | defense response to bacterium |
| E | 0043129 | biological_process | surfactant homeostasis |
| E | 0045087 | biological_process | innate immune response |
| E | 0050891 | biological_process | multicellular organismal-level water homeostasis |
| E | 0061844 | biological_process | antimicrobial humoral immune response mediated by antimicrobial peptide |
| E | 1900229 | biological_process | negative regulation of single-species biofilm formation in or on host organism |
| E | 1902305 | biological_process | regulation of sodium ion transmembrane transport |
| F | 0002376 | biological_process | immune system process |
| F | 0002395 | biological_process | immune response in nasopharyngeal-associated lymphoid tissue |
| F | 0005576 | cellular_component | extracellular region |
| F | 0005615 | cellular_component | extracellular space |
| F | 0005902 | cellular_component | microvillus |
| F | 0008289 | molecular_function | lipid binding |
| F | 0019731 | biological_process | antibacterial humoral response |
| F | 0042742 | biological_process | defense response to bacterium |
| F | 0043129 | biological_process | surfactant homeostasis |
| F | 0045087 | biological_process | innate immune response |
| F | 0050891 | biological_process | multicellular organismal-level water homeostasis |
| F | 0061844 | biological_process | antimicrobial humoral immune response mediated by antimicrobial peptide |
| F | 1900229 | biological_process | negative regulation of single-species biofilm formation in or on host organism |
| F | 1902305 | biological_process | regulation of sodium ion transmembrane transport |
| G | 0002376 | biological_process | immune system process |
| G | 0002395 | biological_process | immune response in nasopharyngeal-associated lymphoid tissue |
| G | 0005576 | cellular_component | extracellular region |
| G | 0005615 | cellular_component | extracellular space |
| G | 0005902 | cellular_component | microvillus |
| G | 0008289 | molecular_function | lipid binding |
| G | 0019731 | biological_process | antibacterial humoral response |
| G | 0042742 | biological_process | defense response to bacterium |
| G | 0043129 | biological_process | surfactant homeostasis |
| G | 0045087 | biological_process | innate immune response |
| G | 0050891 | biological_process | multicellular organismal-level water homeostasis |
| G | 0061844 | biological_process | antimicrobial humoral immune response mediated by antimicrobial peptide |
| G | 1900229 | biological_process | negative regulation of single-species biofilm formation in or on host organism |
| G | 1902305 | biological_process | regulation of sodium ion transmembrane transport |
| H | 0002376 | biological_process | immune system process |
| H | 0002395 | biological_process | immune response in nasopharyngeal-associated lymphoid tissue |
| H | 0005576 | cellular_component | extracellular region |
| H | 0005615 | cellular_component | extracellular space |
| H | 0005902 | cellular_component | microvillus |
| H | 0008289 | molecular_function | lipid binding |
| H | 0019731 | biological_process | antibacterial humoral response |
| H | 0042742 | biological_process | defense response to bacterium |
| H | 0043129 | biological_process | surfactant homeostasis |
| H | 0045087 | biological_process | innate immune response |
| H | 0050891 | biological_process | multicellular organismal-level water homeostasis |
| H | 0061844 | biological_process | antimicrobial humoral immune response mediated by antimicrobial peptide |
| H | 1900229 | biological_process | negative regulation of single-species biofilm formation in or on host organism |
| H | 1902305 | biological_process | regulation of sodium ion transmembrane transport |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 4 |
| Details | binding site for residue NA A 301 |
| Chain | Residue |
| A | THR205 |
| A | HIS206 |
| B | THR205 |
| B | HIS206 |
| site_id | AC2 |
| Number of Residues | 3 |
| Details | binding site for residue NA A 302 |
| Chain | Residue |
| A | THR69 |
| A | ASP70 |
| A | PHE274 |
| site_id | AC3 |
| Number of Residues | 3 |
| Details | binding site for residue NA A 303 |
| Chain | Residue |
| E | GLY91 |
| A | ASP78 |
| E | LEU90 |
| site_id | AC4 |
| Number of Residues | 4 |
| Details | binding site for residue NA A 304 |
| Chain | Residue |
| A | ASN129 |
| A | MET168 |
| A | PRO169 |
| A | VAL170 |
| site_id | AC5 |
| Number of Residues | 1 |
| Details | binding site for residue NA A 305 |
| Chain | Residue |
| A | SER210 |
| site_id | AC6 |
| Number of Residues | 3 |
| Details | binding site for residue NA A 306 |
| Chain | Residue |
| A | PRO65 |
| A | SER66 |
| A | PRO68 |
| site_id | AC7 |
| Number of Residues | 3 |
| Details | binding site for residue NA A 307 |
| Chain | Residue |
| A | LEU174 |
| A | GLN176 |
| A | LEU216 |
| site_id | AC8 |
| Number of Residues | 1 |
| Details | binding site for residue NA A 308 |
| Chain | Residue |
| A | ILE135 |
| site_id | AC9 |
| Number of Residues | 3 |
| Details | binding site for residue NA A 309 |
| Chain | Residue |
| A | PRO149 |
| A | ASP150 |
| A | ARG153 |
| site_id | AD1 |
| Number of Residues | 6 |
| Details | binding site for residue NA A 310 |
| Chain | Residue |
| A | THR69 |
| A | ASP70 |
| A | LEU72 |
| A | ALA73 |
| A | PHE274 |
| A | HOH424 |
| site_id | AD2 |
| Number of Residues | 3 |
| Details | binding site for residue NA A 311 |
| Chain | Residue |
| A | ASP137 |
| E | GLU142 |
| E | HOH417 |
| site_id | AD3 |
| Number of Residues | 4 |
| Details | binding site for residue NA B 301 |
| Chain | Residue |
| B | ILE92 |
| B | ASN95 |
| B | ILE96 |
| B | LYS244 |
| site_id | AD4 |
| Number of Residues | 1 |
| Details | binding site for residue NA B 302 |
| Chain | Residue |
| B | GLY87 |
| site_id | AD5 |
| Number of Residues | 4 |
| Details | binding site for residue NA B 303 |
| Chain | Residue |
| B | PRO149 |
| B | GLN273 |
| F | HIS262 |
| F | NA304 |
| site_id | AD6 |
| Number of Residues | 3 |
| Details | binding site for residue NA B 304 |
| Chain | Residue |
| B | GLY144 |
| B | TYR155 |
| B | THR157 |
| site_id | AD7 |
| Number of Residues | 6 |
| Details | binding site for residue NA B 305 |
| Chain | Residue |
| B | PRO149 |
| B | ASP150 |
| B | GLY151 |
| B | GLY271 |
| B | GLN273 |
| F | HIS262 |
| site_id | AD8 |
| Number of Residues | 2 |
| Details | binding site for residue NA B 306 |
| Chain | Residue |
| B | HIS152 |
| B | ALA189 |
| site_id | AD9 |
| Number of Residues | 5 |
| Details | binding site for residue CL B 307 |
| Chain | Residue |
| B | ASP70 |
| B | LEU71 |
| B | LEU72 |
| B | ALA73 |
| B | PHE274 |
| site_id | AE1 |
| Number of Residues | 4 |
| Details | binding site for residue GOL C 301 |
| Chain | Residue |
| C | ASP150 |
| C | HIS152 |
| C | HIS270 |
| C | GLY271 |
| site_id | AE2 |
| Number of Residues | 2 |
| Details | binding site for residue NA C 302 |
| Chain | Residue |
| C | GLN273 |
| C | VAL275 |
| site_id | AE3 |
| Number of Residues | 4 |
| Details | binding site for residue NA C 303 |
| Chain | Residue |
| C | THR205 |
| C | HIS206 |
| G | THR205 |
| G | HIS206 |
| site_id | AE4 |
| Number of Residues | 1 |
| Details | binding site for residue NA C 304 |
| Chain | Residue |
| C | GLY87 |
| site_id | AE5 |
| Number of Residues | 4 |
| Details | binding site for residue NA C 305 |
| Chain | Residue |
| C | LEU85 |
| C | GLY88 |
| C | LEU89 |
| C | LEU90 |
| site_id | AE6 |
| Number of Residues | 4 |
| Details | binding site for residue NA C 306 |
| Chain | Residue |
| C | VAL200 |
| C | LEU201 |
| C | ASN250 |
| F | SER123 |
| site_id | AE7 |
| Number of Residues | 3 |
| Details | binding site for residue NA C 307 |
| Chain | Residue |
| C | SER81 |
| C | GLU142 |
| C | LEU143 |
| site_id | AE8 |
| Number of Residues | 4 |
| Details | binding site for residue NA C 308 |
| Chain | Residue |
| C | PRO125 |
| C | LEU126 |
| C | ASN128 |
| C | ASN129 |
| site_id | AE9 |
| Number of Residues | 3 |
| Details | binding site for residue NA C 309 |
| Chain | Residue |
| C | VAL258 |
| H | LYS103 |
| H | NA307 |
| site_id | AF1 |
| Number of Residues | 1 |
| Details | binding site for residue NA D 302 |
| Chain | Residue |
| D | ASN263 |
| site_id | AF2 |
| Number of Residues | 2 |
| Details | binding site for residue NA D 303 |
| Chain | Residue |
| D | GLN176 |
| D | LEU216 |
| site_id | AF3 |
| Number of Residues | 4 |
| Details | binding site for residue NA D 304 |
| Chain | Residue |
| D | ASP203 |
| F | GLY209 |
| F | SER210 |
| F | LEU211 |
| site_id | AF4 |
| Number of Residues | 4 |
| Details | binding site for residue NA E 301 |
| Chain | Residue |
| E | THR205 |
| E | HIS206 |
| H | THR205 |
| H | HIS206 |
| site_id | AF5 |
| Number of Residues | 4 |
| Details | binding site for residue NA E 302 |
| Chain | Residue |
| E | THR234 |
| E | LYS235 |
| E | GLU239 |
| H | ASP203 |
| site_id | AF6 |
| Number of Residues | 2 |
| Details | binding site for residue NA E 303 |
| Chain | Residue |
| E | ILE96 |
| E | ILE133 |
| site_id | AF7 |
| Number of Residues | 3 |
| Details | binding site for residue NA E 304 |
| Chain | Residue |
| E | THR69 |
| E | ASP70 |
| E | PHE274 |
| site_id | AF8 |
| Number of Residues | 2 |
| Details | binding site for residue NA E 305 |
| Chain | Residue |
| E | GLN273 |
| E | VAL275 |
| site_id | AF9 |
| Number of Residues | 2 |
| Details | binding site for residue NA E 306 |
| Chain | Residue |
| E | SER210 |
| E | HOH424 |
| site_id | AG1 |
| Number of Residues | 1 |
| Details | binding site for residue NA E 307 |
| Chain | Residue |
| E | LYS244 |
| site_id | AG2 |
| Number of Residues | 2 |
| Details | binding site for residue NA E 308 |
| Chain | Residue |
| E | ASP137 |
| E | THR163 |
| site_id | AG3 |
| Number of Residues | 3 |
| Details | binding site for residue NA E 309 |
| Chain | Residue |
| E | PRO149 |
| E | ASP150 |
| E | ARG153 |
| site_id | AG4 |
| Number of Residues | 3 |
| Details | binding site for residue NA F 301 |
| Chain | Residue |
| F | PRO149 |
| F | ASP150 |
| F | ARG153 |
| site_id | AG5 |
| Number of Residues | 2 |
| Details | binding site for residue NA F 302 |
| Chain | Residue |
| F | PRO68 |
| F | LEU71 |
| site_id | AG6 |
| Number of Residues | 2 |
| Details | binding site for residue NA F 303 |
| Chain | Residue |
| F | ASN182 |
| F | HOH447 |
| site_id | AG7 |
| Number of Residues | 2 |
| Details | binding site for residue NA F 304 |
| Chain | Residue |
| B | NA303 |
| F | HOH467 |
| site_id | AG8 |
| Number of Residues | 3 |
| Details | binding site for residue NA F 305 |
| Chain | Residue |
| F | SER254 |
| F | GLY255 |
| F | LEU256 |
| site_id | AG9 |
| Number of Residues | 2 |
| Details | binding site for residue GOL G 301 |
| Chain | Residue |
| G | PRO208 |
| G | HOH432 |
| site_id | AH1 |
| Number of Residues | 5 |
| Details | binding site for residue NA G 302 |
| Chain | Residue |
| A | GLY172 |
| A | SER173 |
| C | SER224 |
| G | LYS191 |
| G | ASP192 |
| site_id | AH2 |
| Number of Residues | 3 |
| Details | binding site for residue NA G 303 |
| Chain | Residue |
| G | LEU90 |
| G | GLY91 |
| G | HOH416 |
| site_id | AH3 |
| Number of Residues | 1 |
| Details | binding site for residue NA G 304 |
| Chain | Residue |
| G | ASN67 |
| site_id | AH4 |
| Number of Residues | 4 |
| Details | binding site for residue NA G 305 |
| Chain | Residue |
| G | SER254 |
| G | GLY255 |
| G | LEU256 |
| G | HOH430 |
| site_id | AH5 |
| Number of Residues | 3 |
| Details | binding site for residue NA G 306 |
| Chain | Residue |
| G | THR69 |
| G | ASP70 |
| G | PHE274 |
| site_id | AH6 |
| Number of Residues | 2 |
| Details | binding site for residue NA G 307 |
| Chain | Residue |
| G | GLN273 |
| G | VAL275 |
| site_id | AH7 |
| Number of Residues | 4 |
| Details | binding site for residue NA G 308 |
| Chain | Residue |
| C | ASP203 |
| G | THR234 |
| G | PRO238 |
| G | GLU239 |
| site_id | AH8 |
| Number of Residues | 2 |
| Details | binding site for residue NA G 309 |
| Chain | Residue |
| C | THR234 |
| G | ASP203 |
| site_id | AH9 |
| Number of Residues | 2 |
| Details | binding site for residue NA G 310 |
| Chain | Residue |
| G | LEU71 |
| G | LYS75 |
| site_id | AI1 |
| Number of Residues | 2 |
| Details | binding site for residue NA G 311 |
| Chain | Residue |
| G | GLN139 |
| G | HOH441 |
| site_id | AI2 |
| Number of Residues | 1 |
| Details | binding site for residue NA G 312 |
| Chain | Residue |
| G | ILE135 |
| site_id | AI3 |
| Number of Residues | 3 |
| Details | binding site for residue NA G 313 |
| Chain | Residue |
| G | ASP257 |
| G | THR259 |
| H | ILE276 |
| site_id | AI4 |
| Number of Residues | 3 |
| Details | binding site for residue NA G 314 |
| Chain | Residue |
| G | PRO149 |
| G | ASP150 |
| G | ARG153 |
| site_id | AI5 |
| Number of Residues | 5 |
| Details | binding site for residue GOL H 301 |
| Chain | Residue |
| H | ASP150 |
| H | HIS152 |
| H | HIS270 |
| H | HOH402 |
| H | HOH406 |
| site_id | AI6 |
| Number of Residues | 2 |
| Details | binding site for residue GOL H 302 |
| Chain | Residue |
| E | PRO208 |
| H | TYR155 |
| site_id | AI7 |
| Number of Residues | 3 |
| Details | binding site for residue NA H 303 |
| Chain | Residue |
| H | PRO149 |
| H | ASP150 |
| H | ARG153 |
| site_id | AI8 |
| Number of Residues | 4 |
| Details | binding site for residue NA H 304 |
| Chain | Residue |
| H | LEU174 |
| H | GLN176 |
| H | LEU216 |
| H | ASN217 |
| site_id | AI9 |
| Number of Residues | 4 |
| Details | binding site for residue NA H 305 |
| Chain | Residue |
| G | ASN263 |
| G | HOH428 |
| H | GLY271 |
| H | HOH407 |
| site_id | AJ1 |
| Number of Residues | 5 |
| Details | binding site for residue NA H 307 |
| Chain | Residue |
| C | NA309 |
| H | LYS103 |
| H | LEU127 |
| H | ASN128 |
| H | ILE130 |
| site_id | AJ2 |
| Number of Residues | 2 |
| Details | binding site for residue NA H 308 |
| Chain | Residue |
| H | LEU256 |
| H | ASP257 |
| site_id | AJ3 |
| Number of Residues | 4 |
| Details | binding site for residue NA H 309 |
| Chain | Residue |
| F | VAL170 |
| F | VAL171 |
| F | GLY172 |
| H | ASN228 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 16 |
| Details | Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 5 |
| Details | Region: {"description":"Important for surfactant activity and antibacterial properties","evidences":[{"source":"UniProtKB","id":"Q9NP55","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
