6B9P

Structure of GH 38 Jack Bean alpha-mannosidase in complex with a 36-valent iminosugar cluster inhibitor

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000326	cellular_component	protein storage vacuole
A	0003824	molecular_function	catalytic activity
A	0004559	molecular_function	alpha-mannosidase activity
A	0005975	biological_process	carbohydrate metabolic process
A	0006013	biological_process	mannose metabolic process
A	0016787	molecular_function	hydrolase activity
A	0016798	molecular_function	hydrolase activity, acting on glycosyl bonds
A	0030246	molecular_function	carbohydrate binding
A	0046872	molecular_function	metal ion binding
B	0000326	cellular_component	protein storage vacuole
B	0003824	molecular_function	catalytic activity
B	0004559	molecular_function	alpha-mannosidase activity
B	0005975	biological_process	carbohydrate metabolic process
B	0006013	biological_process	mannose metabolic process
B	0016787	molecular_function	hydrolase activity
B	0016798	molecular_function	hydrolase activity, acting on glycosyl bonds
B	0030246	molecular_function	carbohydrate binding
B	0046872	molecular_function	metal ion binding

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	2
Details	Active site: {"description":"Nucleophile","evidences":[{"source":"PubMed","id":"9442045","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI2
Number of Residues	8
Details	Binding site: {"evidences":[{"source":"UniProtKB","id":"Q29451","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI3
Number of Residues	4
Details	Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"source":"PubMed","id":"24295789","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

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